Condition

Crohn's disease

Crohn's disease news across medications, symptoms, tests, procedures, complications, research, access, and daily life.

Page 12 of 53 · 2517 articles

Trendy, but Are They Safe? Current Popular Diets and Their Use in Inflammatory Bowel Diseases: Narrative Review
Nutrients

Trendy, but Are They Safe? Current Popular Diets and Their Use in Inflammatory Bowel Diseases: Narrative Review

Diet is a modifiable factor many people with IBD try to use to manage symptoms and disease; this review summarizes what is and isn’t supported by current evidence for popular diets and structured nutritional therapies.

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Impact of Smoking on the Effectiveness of Advanced Therapies in Inflammatory Bowel Disease: Active Smoking Is Associated with Reduced Effectiveness of Anti-TNF Treatment
Medicina

Impact of Smoking on the Effectiveness of Advanced Therapies in Inflammatory Bowel Disease: Active Smoking Is Associated with Reduced Effectiveness of Anti-TNF Treatment

The study suggests active smoking reduces the effectiveness of anti-TNF biologics in people with IBD, which could affect treatment response and the need to switch or escalate therapies. This supports including smoking...

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Patterns and factors associated with dose escalation during maintenance treatment for inflammatory bowel disease: a population-based cohort study.
Sage open chronic disease

Patterns and factors associated with dose escalation during maintenance treatment for inflammatory bowel disease: a population-based cohort study.

Dose increases are common during IBD maintenance and vary a lot by drug and patient profile. Knowing which treatments and patient factors are linked to escalation can help patients and clinicians plan monitoring and...

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Patient-reported first-use usability of the noncommercial MyTARGET mobile application among adults with inflammatory bowel disease: a cross-sectional survey.
Frontiers in digital health

Patient-reported first-use usability of the noncommercial MyTARGET mobile application among adults with inflammatory bowel disease: a cross-sectional survey.

High first-use usability suggests MyTARGET could be acceptable to many adults with IBD and that targeted refinements (error handling, demonstrating time savings) might improve uptake and recommendation.

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Creeping Fat in Crohn's Disease: Association or Prognostic Factor?
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology

Creeping Fat in Crohn's Disease: Association or Prognostic Factor?

Based on the title and source metadata, this appears to be a clinical study related to Crohn's disease, Inflammatory bowel disease, and Research and clinical trials. The original article is from The Turkish journal of...

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A Reproducible Bibliometric Analysis of Perianal Fistula in Crohn's Disease Research (1992-2025): Retrieval Sensitivity and Knowledge Structure.
Journal of visualized experiments : JoVE

A Reproducible Bibliometric Analysis of Perianal Fistula in Crohn's Disease Research (1992-2025): Retrieval Sensitivity and Knowledge Structure.

A bibliometric map of perianal fistula research helps patients and clinicians see how much work exists, which centers and authors lead the field, and which topics cluster together—useful when looking for expertise or...

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Evaluation of Blood and Stool Biomarkers Across Three Fecal Calprotectin Platforms and Combination Testing for Predicting Endoscopic and Histologic Outcomes in Inflammatory Bowel Disease
Europe PMC

Evaluation of Blood and Stool Biomarkers Across Three Fecal Calprotectin Platforms and Combination Testing for Predicting Endoscopic and Histologic Outcomes in Inflammatory Bowel Disease

Noninvasive fecal biomarkers are widely used to track IBD activity. Knowing whether different FC assays give comparable results and whether combining tests adds value affects how patients and clinicians interpret...

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Ulcerative colitis, but not Crohn’s disease, displays demographically and clinically driven mucosal immune heterogeneity: implications for patient stratification
Frontiers in Immunology

Ulcerative colitis, but not Crohn’s disease, displays demographically and clinically driven mucosal immune heterogeneity: implications for patient stratification

The study suggests ulcerative colitis shows greater mucosal immune variability across sex, age and severity than Crohn’s disease, which could affect how patients are grouped for research or future personalized...

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Multicentre, prospective, observational study on the effectiveness and safety of upadacitinib for active perianal fistulising Crohn's disease in patients with prior anti-tumour necrosis factor failure: a study protocol.
BMJ open

Multicentre, prospective, observational study on the effectiveness and safety of upadacitinib for active perianal fistulising Crohn's disease in patients with prior anti-tumour necrosis factor failure: a study protocol.

Perianal fistulising Crohn's disease is hard to treat and often fails anti-TNF drugs. This study will provide real-world data on whether upadacitinib can be effective and safe for patients with refractory perianal...

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Preexisting depression and early outcomes in inflammatory bowel disease: a propensity score-matched cohort study.
Proceedings (Baylor University. Medical Center)

Preexisting depression and early outcomes in inflammatory bowel disease: a propensity score-matched cohort study.

Depression before an IBD diagnosis was linked to more early treatment escalation and acute-care use after diagnosis. Recognizing preexisting depression could help clinicians identify patients who may benefit from closer...

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Study to Assess Treatment Patterns and Outcomes With Upadacitinib in Adult Participants With Inflammatory Bowel Disease in Belgium
ClinicalTrials.gov

Study to Assess Treatment Patterns and Outcomes With Upadacitinib in Adult Participants With Inflammatory Bowel Disease in Belgium

Real-world registry data on upadacitinib can help patients and clinicians understand how the drug performs outside clinical trials, including patterns of use, effectiveness, and safety over time.

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Intracorporeal Versus Extracorporeal Anastomosis in Minimally Invasive Ileocecectomy or Ileocolic Resection for Crohn's Disease: A Systematic Review and Meta-Analysis.
Journal of laparoendoscopic & advanced surgical techniques. Part A

Intracorporeal Versus Extracorporeal Anastomosis in Minimally Invasive Ileocecectomy or Ileocolic Resection for Crohn's Disease: A Systematic Review and Meta-Analysis.

This systematic review focuses on two ways surgeons reconnect the bowel after minimally invasive right-sided surgery for Crohn’s disease. It found fewer overall postoperative complications with intracorporeal anastomosis...

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The role of blood lymphocyte levels in evaluating endoscopic remission of inflammatory bowel disease
European journal of medical research

The role of blood lymphocyte levels in evaluating endoscopic remission of inflammatory bowel disease

A simple blood lymphocyte percentage could be a convenient, non-invasive marker to help distinguish endoscopic remission from active disease in both Crohn’s and ulcerative colitis; chemokines CXCL10 and CCL25 may also...

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Distribution of CARD15/NOD2 Variants in Crohn’s Disease, Ulcerative Colitis, and Healthy Controls in a Djiboutian Population
Gastrointestinal Disorders

Distribution of CARD15/NOD2 Variants in Crohn’s Disease, Ulcerative Colitis, and Healthy Controls in a Djiboutian Population

The report explores NOD2/CARD15 variants in a Djiboutian IBD cohort and suggests higher variant frequencies in Crohn’s disease, which could point to population-specific genetic susceptibility. It also raises khat use as...

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Extracellular vesicle-based therapies in IBD: immunomodulation, regeneration, and translation.
Frontiers in immunology

Extracellular vesicle-based therapies in IBD: immunomodulation, regeneration, and translation.

Extracellular vesicle (EV) therapies are being explored as new ways to modulate immune responses and promote mucosal repair in IBD, which could eventually expand treatment options beyond current biologics and small...

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Rising burden of inflammatory Bowel disease in Northeastern Italy: a population-based analysis of prevalence and incidence trends from 2012 to 2024.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

Rising burden of inflammatory Bowel disease in Northeastern Italy: a population-based analysis of prevalence and incidence trends from 2012 to 2024.

The study documents substantial increases in Crohn’s disease and ulcerative colitis prevalence and changing incidence patterns in Northeastern Italy from 2012–2024, which may affect healthcare demand and resource...

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Revisiting the role of lymphatics in Crohn’s disease
Inflammatory Bowel Diseases

Revisiting the role of lymphatics in Crohn’s disease

If lymphatic dysfunction helps cause or sustain Crohn’s inflammation, it could explain some classic disease features (patchy, transmural inflammation and mesenteric changes) and point to new treatment approaches aimed at...

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