Condition

Crohn's disease

Crohn's disease news across medications, symptoms, tests, procedures, complications, research, access, and daily life.

Page 13 of 33 · 1547 articles

Current and emerging therapeutic strategies targeting adherent-invasive Escherichia coli in Crohn’s disease: a review
Gut Pathogens

Current and emerging therapeutic strategies targeting adherent-invasive Escherichia coli in Crohn’s disease: a review

Adherent-invasive E. coli (AIEC) is implicated in Crohn’s disease inflammation in some patients. This review maps possible ways to target AIEC specifically, which could lead to therapies that reduce infection-driven...

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Factors associated with preference for in-person versus remote consultations in inflammatory bowel disease in the United Kingdom: secondary analysis of an online survey.
European journal of gastroenterology & hepatology

Factors associated with preference for in-person versus remote consultations in inflammatory bowel disease in the United Kingdom: secondary analysis of an online survey.

Patients and clinics are still deciding how much care can be done remotely. Knowing who prefers in-person versus remote visits helps tailor care so patients receive the visit type they need and want, and supports...

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Hierarchical correlates of sexual dysfunction in inflammatory bowel disease: Psychological burden outweighs disease activity and sarcopenia.
Journal of psychosomatic research

Hierarchical correlates of sexual dysfunction in inflammatory bowel disease: Psychological burden outweighs disease activity and sarcopenia.

Sexual dysfunction is common in IBD and—according to this study—appears more strongly linked to psychological and demographic factors than to disease activity or muscle loss. Recognizing and treating mental-health issues...

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Feasibility, Acceptability, and Preliminary Effects of a Nurse-Delivered Self-Management Program for Individuals with Inflammatory Bowel Disease: A Pilot Randomized Controlled Trial
Digestive Diseases and Sciences

Feasibility, Acceptability, and Preliminary Effects of a Nurse-Delivered Self-Management Program for Individuals with Inflammatory Bowel Disease: A Pilot Randomized Controlled Trial

Self‑management programs delivered by nurses may help people with IBD improve daily functioning, confidence in managing their condition, and quality of life even when inflammation markers don’t change. That matters...

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Co-Occurring Autoimmune Disease in Crohn's Disease Versus Ulcerative Colitis: Complementary Data From a Diverse Urban Cohort.
Journal of gastroenterology and hepatology

Co-Occurring Autoimmune Disease in Crohn's Disease Versus Ulcerative Colitis: Complementary Data From a Diverse Urban Cohort.

Cure8 found this source from Journal of gastroenterology and hepatology, but the page could not be read reliably yet. It is tagged for Crohn's disease, Ulcerative colitis, and Inflammatory bowel disease. Open the...

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Co‐Occurring Autoimmune Disease in Crohn's Disease Versus Ulcerative Colitis: Complementary Data From a Diverse Urban Cohort
Journal of Gastroenterology and Hepatology

Co‐Occurring Autoimmune Disease in Crohn's Disease Versus Ulcerative Colitis: Complementary Data From a Diverse Urban Cohort

Based on the title and source metadata, this appears to be a clinical study related to Crohn's disease, Ulcerative colitis, and Inflammatory bowel disease. The original article is from Journal of Gastroenterology and...

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Absolute risk of malignancy by treatment in patients with Crohn's disease compared to the general population: a nationwide population-based cohort study.
The American journal of gastroenterology

Absolute risk of malignancy by treatment in patients with Crohn's disease compared to the general population: a nationwide population-based cohort study.

People with Crohn's disease and their clinicians often ask how different treatments affect cancer risk. This large nationwide study provides real-world estimates of absolute excess cancer cases by treatment group, which...

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A Study of LY4395089 and Mirikizumab (LY3074828) Given Together and Mirikizumab (Alone) in Adults With Crohn's Disease
ClinicalTrials.gov

A Study of LY4395089 and Mirikizumab (LY3074828) Given Together and Mirikizumab (Alone) in Adults With Crohn's Disease

This trial tests whether adding an FXR agonist (LY4395089) to mirikizumab improves endoscopic response in people with moderate–severe Crohn's disease. Results could influence future combination treatment strategies and...

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A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community Setting
ClinicalTrials.gov

A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community Setting

This trial tests a common real-world question: switching from IV induction to subcutaneous vedolizumab maintenance in adults with moderate-to-severe UC or CD and measures short-term remission and longer-term treatment...

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Relationship between sacroiliac joint involvement and intestinal disease activity in newly diagnosed Crohn's disease.
BMC gastroenterology

Relationship between sacroiliac joint involvement and intestinal disease activity in newly diagnosed Crohn's disease.

If you have newly diagnosed Crohn’s disease, this study suggests sacroiliac joint inflammation or structural SIJ changes can already be present and may relate to microscopic (histologic) intestinal activity.

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Modernizing Aeromedical Standards for Crohn's Disease: A Risk-Stratified, Evidence-Informed Proposal for Waiver Reform.
Military medicine

Modernizing Aeromedical Standards for Crohn's Disease: A Risk-Stratified, Evidence-Informed Proposal for Waiver Reform.

This is relevant because military aviators with Crohn’s disease have historically been excluded from waivers; policy changes could allow some stable patients to continue flying if objective evidence supports low...

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Development And Validation of UV-Spectrophotometric Method for Determination of Upadacitinib Bulk and in Tablet Dosage Form
Journal of Drug Delivery and Therapeutics

Development And Validation of UV-Spectrophotometric Method for Determination of Upadacitinib Bulk and in Tablet Dosage Form

Reliable laboratory methods help ensure upadacitinib tablets contain the correct amount of drug and support quality control of medicines people take for conditions including Crohn’s disease and ulcerative colitis.

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Urinary Organic Acid Profiling by GC-MS Reveals Distinct Metabolic Signatures for Non-Invasive Diagnosis and Disease Activity Monitoring of Inflammatory Bowel Disease
International Journal of Molecular Sciences

Urinary Organic Acid Profiling by GC-MS Reveals Distinct Metabolic Signatures for Non-Invasive Diagnosis and Disease Activity Monitoring of Inflammatory Bowel Disease

Non-invasive urine biomarkers could make diagnosis and disease-activity monitoring easier and less invasive for people with IBD. Identifying metabolites linked to UC activity may help tailor monitoring without frequent...

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Proactive therapeutic drug monitoring of infliximab leads to treatment durability in paediatric Crohn's disease: A single‐centre Australian experience
JPGN Reports

Proactive therapeutic drug monitoring of infliximab leads to treatment durability in paediatric Crohn's disease: A single‐centre Australian experience

Proactive TDM of infliximab was associated with high 1‑ and 2‑year durability in this pediatric Crohn's cohort, and the study flags clinical factors that may predict need to switch biologics. This could be relevant when...

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Role of Fatty Acid Oxidation in Crohn's Disease and Ulcerative Colitis: Metabolomics Analysis and Experimental Evidence
PubMed Central

Role of Fatty Acid Oxidation in Crohn's Disease and Ulcerative Colitis: Metabolomics Analysis and Experimental Evidence

The study links depleted fatty acid oxidation metabolites—especially butyrate—to impaired regulatory T cell development in IBD, suggesting a metabolic pathway that may influence immune tolerance and disease activity.

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Inflammatory marker profiles vary by BMI across Crohn’s disease, ulcerative colitis, psoriasis, and psoriatic arthritis
Frontiers in Endocrinology

Inflammatory marker profiles vary by BMI across Crohn’s disease, ulcerative colitis, psoriasis, and psoriatic arthritis

Markers of systemic inflammation (CRP and ESR) were consistently higher in people with obesity across Crohn’s disease, ulcerative colitis, psoriasis, and psoriatic arthritis, suggesting body weight may influence...

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Subcutaneous infliximab as a maintenance option in pediatric IBD: a real-world cohort including younger and lower-weight children.
Molecular and cellular pediatrics

Subcutaneous infliximab as a maintenance option in pediatric IBD: a real-world cohort including younger and lower-weight children.

Subcutaneous infliximab may let children on infliximab avoid regular IV infusions while keeping drug levels high and maintaining remission. Results are relevant to families and clinicians considering switching pediatric...

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Fibroblast activation protein inhibitor PET/computed tomography versus 18F-fluorodeoxyglucose PET/computed tomography in inflammatory bowel disease: a systematic review and exploratory meta-analysis with focus on ulcerative colitis.
Nuclear medicine communications

Fibroblast activation protein inhibitor PET/computed tomography versus 18F-fluorodeoxyglucose PET/computed tomography in inflammatory bowel disease: a systematic review and exploratory meta-analysis with focus on ulcerative colitis.

New PET tracers like FAPI could better detect fibrosis and stromal activity than standard FDG-PET, which may improve imaging of fibrostenotic Crohn's disease. For people with IBD, improved imaging might eventually help...

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Intestinal ultrasound in inflammatory bowel disease: diagnostic accuracy and impact on clinical decision making in a New Zealand tertiary centre.
The New Zealand medical journal

Intestinal ultrasound in inflammatory bowel disease: diagnostic accuracy and impact on clinical decision making in a New Zealand tertiary centre.

Point-of-care intestinal ultrasound (IUS) showed strong agreement with follow-up tests and often changed management the same day in a New Zealand IBD cohort. Patients and clinicians may be able to use IUS to monitor...

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Atopic Dermatitis and Risk of Inflammatory Bowel Disease in Children: A Systematic Review and Meta-Analysis
Cureus

Atopic Dermatitis and Risk of Inflammatory Bowel Disease in Children: A Systematic Review and Meta-Analysis

This review found that children with atopic dermatitis have a modestly higher risk of later developing IBD (both Crohn’s disease and ulcerative colitis). Awareness of this association may help clinicians and families...

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Demographic Analysis of Patients With Ulcerative Colitis Undergoing Restorative Proctocolectomy With Ileal Pouch-Anal Anastomosis: A Single-Center Retrospective Study.
Cureus

Demographic Analysis of Patients With Ulcerative Colitis Undergoing Restorative Proctocolectomy With Ileal Pouch-Anal Anastomosis: A Single-Center Retrospective Study.

Pouch surgery is a key restorative option for people with ulcerative colitis, but pouchitis, chronic antibiotic-refractory pouchitis (CARP), pouch failure, and occasional reclassification to Crohn’s disease can cause...

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Causal Insights Into Crohn's Disease: The Role of Oxidative Stress and Genetic Variants.
Journal of cellular and molecular medicine

Causal Insights Into Crohn's Disease: The Role of Oxidative Stress and Genetic Variants.

People with Crohn’s may be interested because the study links oxidative stress and specific genes to disease activity, which could inform future biomarkers or treatments. It helps explain biological pathways behind...

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Time trends in strategies for postoperative Crohn's disease management and long-term surgical recurrence: ENEIDA registry data.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Time trends in strategies for postoperative Crohn's disease management and long-term surgical recurrence: ENEIDA registry data.

The findings suggest that over three decades more patients receive medical prevention after ileocolic resection — including thiopurines and biologics — and that rates of needing a second surgery have fallen. This matters...

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Utility of endoscopic ileocecal valve-plasty for Crohn's disease: a propensity-matched retrospective study.
Surgical endoscopy

Utility of endoscopic ileocecal valve-plasty for Crohn's disease: a propensity-matched retrospective study.

People with Crohn’s disease and fibrotic ileocecal valve strictures sometimes face surgery when endoscopic access is blocked by polypoid tissue. A new endoscopic approach (ICVP) aims to remove obstructing tissue so...

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Extracellular vesicles produced by Malassezia commensal yeasts.
Extracellular vesicles and circulating nucleic acids

Extracellular vesicles produced by Malassezia commensal yeasts.

Malassezia extracellular vesicles can modulate immune and microbial interactions; if similar mechanisms affect the gut, they could be relevant to inflammatory bowel disease and Crohn’s disease, though current evidence is...

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Presentation and Clinical Outcomes of Inflammatory Bowel Disease in Children and Adolescents at a Tertiary Care Center in Lebanon.
Journal of clinical medicine

Presentation and Clinical Outcomes of Inflammatory Bowel Disease in Children and Adolescents at a Tertiary Care Center in Lebanon.

This study describes how IBD presents and early outcomes in children at a tertiary center, noting high rates of inflammation, nutritional problems, and early flares. Findings may help families and clinicians understand...

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Current and novel biomarkers for predicting and assessing therapeutic response in inflammatory bowel disease: a systematic review.
Therapeutic advances in gastroenterology

Current and novel biomarkers for predicting and assessing therapeutic response in inflammatory bowel disease: a systematic review.

People with IBD and their clinicians want ways to predict which advanced therapy will work best. This review summarizes current evidence and shows that, despite many studies, no biomarker is reliably ready for routine...

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