Condition
Ulcerative colitis news across medications, symptoms, monitoring, procedures, research, access, and daily life.
Page 15 of 40 · 1919 articles
This study suggests a new preclinical approach to help the gut lining heal in ulcerative colitis by targeting macrophage metabolism (myeloid AMPK) rather than directly treating epithelial cells. That could matter for...
A national pediatric IBD registry from Colombia summarizes diagnosis age, disease types, treatment patterns (including rising biologic use), and outcomes—information that can inform families and clinicians about regional...
Based on the title and source metadata, this appears to be a case report related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Immunity, inflammation...
This matters because it documents organising pneumonia occurring during biomarker-confirmed UC remission and emphasizes that lung disease in IBD patients may be disease-intrinsic rather than always drug-induced. Expert...
The study describes a new berberine-containing nanocomplex that reduced inflammation and improved gut barrier function in cell, mouse, and organoid models of ulcerative colitis, suggesting a potential new direction for...
This article explains why two widely used IBD drugs from AbbVie (Skyrizi and Rinvoq) are central to the company’s growth and describes ongoing development efforts that could expand treatment options and indications in...
Cure8 could only read part of this source from Frontline Gastroenterology, so this card uses cautious topic tags instead of a full summary. It is tagged for Ulcerative colitis, Inflammatory bowel disease, and Infliximab.
Knowing a patient’s estimated infliximab clearance before starting rescue therapy for acute severe ulcerative colitis could help identify who may need higher or intensified induction dosing and who might be at greater...
If confirmed, differences between tirzepatide and GLP-1RAs could influence medication choice for people with IBD who need weight-loss or glucose-lowering therapy. Reduced IV steroid use suggests fewer severe flares...
The study suggests there may be stage-specific differences in mucosal IgA and IgG plasma cell patterns in UC, which could help researchers understand mucosal immunity changes across active disease, quiescence, and...
This trial tests whether oral vancomycin can help children with atypical ulcerative colitis or PSC-associated colitis and whether changes in gut bacteria or metabolites explain response. If effective and safe, it could...
Phase 3 trials test whether a new oral therapy can induce remission in people with moderate-to-severe ulcerative colitis who have not responded to or cannot tolerate existing treatments. If positive, results could add...
Knowing which treatment target (symptom control alone versus adding endoscopic and histological remission) leads to better long-term outcomes could change how aggressively clinicians treat ulcerative colitis and what...
Phase 3 trials test whether a new drug is effective and safe enough to be considered for clinical use. ABX464 is being evaluated as a potential new oral treatment for people with moderate-to-severe ulcerative colitis who...
Intestinal ultrasound can assess IBD inflammation without radiation but interpretation varies by operator. Developing AI tools to measure bowel wall thickness and other features could standardize and speed image...
If confirmed in clinical trials, targeting NAD+ metabolism or removing senescent immune cells could become new approaches to treat ulcerative colitis, especially for patients with severe disease or who do not respond to...
Work participation and sick leave affect daily life, income, and quality of life for people with IBD. Understanding when sick leave is more common can help patients, employers, and clinicians plan support around...
Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Computer Methods in...
Dexamethasone is a systemic corticosteroid with an official label that still includes short‑term use to "tide the patient over a critical period" in Crohn's disease (regional enteritis) and ulcerative colitis.
Patients and clinicians want to know whether tofacitinib raises blood clotting or platelet activation risk in ulcerative colitis, because similar safety concerns were reported in other diseases.
The study suggests a probiotic–ω‑3 combination (a synbiotic) might boost the anti‑inflammatory, pro‑resolving effects of ω‑3s in colonic tissue—potentially relevant for people with ulcerative colitis looking for adjunct...
IL-22 links microbial metabolites to epithelial repair and inflammation; clarifying these pathways could inform future therapies or dietary/microbiome approaches to promote mucosal healing without worsening inflammation.
The paper presents a validated lab method to detect and quantify enantiomeric impurities in upadacitinib, which supports drug quality and safety for patients treated with JAK‑1 inhibitors for IBD and other conditions.
Real-world 52-week data suggest mirikizumab can produce meaningful remission and reasonable drug persistence in patients with treatment-experienced ulcerative colitis. This is especially relevant for people who have not...
Simple, routinely measured nutritional scores were associated with early (14-week) remission on vedolizumab in patients with moderate-to-severe UC, which could help identify patients more likely to respond early to this...
Patients with hidradenitis suppurativa have higher baseline IBD risk, and IL-17 inhibitors are effective HS treatments. People with Crohn’s disease or ulcerative colitis (or those at risk) may worry whether these drugs...
The study links a specific gut microbe and its metabolite to reduced inflammation and improved barrier function in ulcerative colitis models and cohort comparisons, suggesting a potential new microbiome-targeted therapy...
People with IBD who need shoulder replacement may face higher short-term risks after surgery, including infections, pneumonia, sepsis, emergency visits, and a greater chance of needing revision operations. Knowing this...
Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Biomarkers. The original article is from Biochemia medica.
The study suggests ADHD and autism are linked with slightly higher risk of more severe IBD events (including need for advanced therapies and, for UC, colectomy), which may help target monitoring and support for young...
This study suggests that a confirmed Campylobacter stool infection in people with IBD was followed by higher rates of flare and need for treatment escalation within 12 months, so infected patients might need closer...
Patients cared for in accredited IBD units reported better experience and higher satisfaction in this study, which suggests that accreditation may improve patient-centred aspects of care even if self-reported disease...
A validated Spanish IBD-Disk gives Spanish-speaking patients and clinicians a brief, validated tool to measure disability and global health in IBD, supporting consistent monitoring and research across Spanish-speaking...
Better endoscopic classification of flat-type dysplasia could improve surveillance accuracy for people with long-standing ulcerative colitis, helping identify lesions that need biopsy or more urgent management.
This trial describes a large Phase 3 extension study collecting long-term safety and tolerability data for tulisokibart (MK-7240), an investigational TL1A-targeting antibody for Crohn’s disease and ulcerative colitis....
Psychological distress is common in IBD and often goes unaddressed; a peer-led virtual program could expand access to emotional support and inform larger trials if found feasible and acceptable.
This registry could collect real-world outcome data about hyperbaric oxygen therapy for many conditions that sometimes overlap with IBD care (Crohn’s disease, ulcerative colitis, pouchitis, rectovaginal fistula).
This trial tests an oral live biotherapeutic (MH002) aimed at restoring a healthier gut microbiome in people with mild-to-moderate ulcerative colitis. If effective and safe, it would offer a non-immunosuppressive,...
Differences in urbanisation and socioeconomic development may help explain rising IBD rates in newly industrialised regions and point to where earlier diagnosis and healthcare planning might be needed. The association...
The findings highlight that older adults are less likely to be prescribed advanced IBD therapies, which could reflect prescribing patterns, comorbidities, insurance factors, or access issues relevant to treatment...
Identifies a molecule (CCL3) linked to more severe inflammation in IBD tissues, which could help researchers develop new biomarkers or treatments targeting immune-cell recruitment and polarization.
The study suggests higher dietary antioxidant intake (measured by CDAI) may be linked to lower Crohn's disease risk and that inflammation biomarkers could partly explain the association—information potentially relevant...
Targeted oral delivery of melatonin could reduce inflammation and help repair the intestinal barrier in UC by acting on macrophages and epithelial cells. If translated to humans, this approach might offer a locally...
The study connects a bothersome UC symptom (bowel urgency) to intestinal ultrasound signs of transmural inflammation, suggesting ultrasound might help explain and track symptom-related inflammation without relying solely...
Identifies a stromal-cell subset marked by TIMP1 that may play a role in UC pathogenesis and might serve as a candidate biomarker or therapeutic target; useful for researchers and clinicians following emerging...
Better automated scoring tools for endoscopic images could reduce variability between human reviewers and help standardize assessments of ulcerative colitis severity used for treatment decisions and monitoring.
The study reports anti-inflammatory and antioxidant effects of a new andrographolide formulation in a macrophage model relevant to ulcerative colitis, highlighting a potential early-stage therapeutic lead that may...
People with IBD are often interested in how dietary fibers and the microbiome might influence inflammation.
