Nutrition, food, supplements, exercise, sleep, stress, and lifestyle research for Crohn's disease and IBD.
Page 6 of 24 · 1124 articles
Antibiotics can substantially change gut microbes; for people with IBD those changes may affect inflammation and gut barrier function. The review summarizes microbiome-targeted strategies that patients and clinicians may...
If confirmed, genetic evidence that higher omega-3 levels or a lower omega-6/omega-3 ratio relate to lower Crohn’s disease risk could point to biological pathways worth studying and might guide research into prevention...
People with IBD in remission commonly continue to have IBS-like symptoms; this review summarizes randomized trial evidence for symptom-directed treatments and finds no definitive best option.
Researchers are exploring natural compounds that might modulate immune pathways implicated in IBD. This study highlights ergothioneine as a bioactive mushroom compound that reduces pro-inflammatory signals in immune...
This review reframes IBD as a systemic disease influenced by gut microbes, metabolism, and immune interactions — which matters because it points toward better ways to stratify patients, monitor disease, and personalize...
Dietary choices can affect disease activity, remission maintenance, nutrition status, and quality of life for people with IBD. This review summarizes current, evidence-based, phase-specific guidance that can inform care.
This study suggests a specific four-strain probiotic cocktail may better protect against experimental colitis than the three-strain mix, potentially via microbiota-driven increases in spermidine — a microbial metabolite...
People with IBD may be interested because the review highlights a class of dietary polyphenols that could influence inflammation and immune pathways involved in Crohn’s disease and ulcerative colitis. It summarizes...
Many people with IBD want to be active but face symptom-related and psychosocial barriers; low awareness but strong interest in Adapted Physical Activity programs suggests opportunity to add structured, personalized...
Diet and meal preparation can affect comfort and symptom management for many people with IBD. Free, curated recipe tools make it easier to find meals suited to sensitive digestive tracts without trial-and-error.
People with ulcerative colitis may be interested in plant-based therapies that could reduce gut inflammation or support mucosal health. This review compiles preclinical evidence suggesting Terminalia arjuna has...
This review highlights a plant-derived compound, ferulic acid, that showed anti-colitis effects in experimental studies, suggesting a potential new adjunctive therapy pathway worth watching for future clinical research.
Dietary approaches that reduce gut inflammation could offer a low‑risk option to help manage symptoms and biomarkers in Crohn’s disease. This trial specifically tests a catered anti‑inflammatory diet and measures fecal...
If true, prenatal and early-life exposures could influence long-term IBD risk by shaping immune development and the gut microbiome, which may help explain why some people develop IBD and others don’t.
Diet is a modifiable factor many people with IBD try to use to manage symptoms and disease; this review summarizes what is and isn’t supported by current evidence for popular diets and structured nutritional therapies.
The study suggests active smoking reduces the effectiveness of anti-TNF biologics in people with IBD, which could affect treatment response and the need to switch or escalate therapies. This supports including smoking...
Patients and clinicians often face trade-offs when managing overlapping immune-mediated diseases. This report shows how past thromboembolic events and disease remission status can steer therapy away from JAK inhibitors...
Malnutrition is common but under-recognized in ulcerative colitis; a simple, more sensitive screening tool could help clinicians find patients who need nutritional assessment and support earlier.
This identifies a metabolism-related epithelial gene (PCK1) linked to inflammation in UC and suggests acetyl‑L‑carnitine can partially reverse those changes in cell and mouse models—information that could guide future...
Supplements can worsen GI symptoms or interact with Crohn’s disease and its treatments. Knowing which products commonly cause problems can help avoid flares, masking of bleeding, or unnecessary side effects.
A colon-targeted, enzyme-activated imaging probe could help distinguish early versus late inflammatory stages in IBD and provide a noninvasive fecal fluorescence signal—potentially improving disease monitoring beyond...
The review highlights marine polysaccharides as multi-target agents that could modulate inflammation, the microbiome, and the gut barrier—processes central to ulcerative colitis—and points to possible roles as functional...
A protein bar marketed for digestibility may appeal to people with Crohn’s, ulcerative colitis, or other IBD-related digestive sensitivity who struggle to find convenient, protein-rich snacks. The company’s community...
The study identifies a food-industry by-product (crayfish shells) as a source of peptides that reduced inflammation and improved barrier and antioxidant markers in cell and mouse colitis models—research that could inform...
Many people with Crohn’s or colitis struggle to find convenient snacks that are easy to digest and provide protein. A company launching bars designed with digestibility in mind may be of practical interest to those...
The report explores NOD2/CARD15 variants in a Djiboutian IBD cohort and suggests higher variant frequencies in Crohn’s disease, which could point to population-specific genetic susceptibility. It also raises khat use as...
The paper links specific gut bacteria, inflammatory cytokines, and two microRNAs with UC activity, which could point toward new diagnostic biomarkers or targets for research into disease mechanisms.
Dietary macronutrients affect microbiota, barrier integrity, and mucosal immunity in ways that could alter IBD activity. Understanding these pathways could inform more targeted dietary strategies beyond generic...
Extracellular vesicle (EV) therapies are being explored as new ways to modulate immune responses and promote mucosal repair in IBD, which could eventually expand treatment options beyond current biologics and small...
Persistent diarrhea is a common, quality-of-life–limiting problem in ulcerative colitis; this review synthesizes how epithelial transport, barrier damage, immune signaling, mitochondria, and microbiota interact and...
Researchers have found a short peptide in potato protein with antioxidant and anti-inflammatory properties and are testing it as a possible oral treatment for intestinal inflammation — a potential new, plant-derived...
Based on the title and source metadata, this appears to be a patient education related to Crohn's disease, Inflammatory bowel disease, and Diet and lifestyle. The original article is from msn.com.
Malnutrition was common in this group and linked to lower fistula healing and a higher chance of needing proctectomy or abdominal surgery — outcomes that matter to people with perianal Crohn’s disease.
Based on the title and source metadata, this appears to be a clinical study related to Ustekinumab, IL-12/23 inhibitor, and Medications. The original article is from idp.nature.com.
A pro athlete’s experience with perianal Crohn’s disease shows how chronic pain and major surgery can disrupt training and life, and offers practical strategies (advocacy, rehab, pacing) that other people with IBD may...
A multimodal program combining exercise, diet, and psychological support could offer practical, nonpharmacologic ways to improve fitness, quality of life, and potentially treatment outcomes in people with ulcerative...
Microbial amino-acid metabolites may be active players in IBD biology and could become useful biomarkers or therapeutic targets. Understanding these metabolites helps explain links between the microbiome, immune...
The study suggests quercetin can reduce inflammation and tissue damage markers in lab models of ulcerative colitis, pointing to ERK–MMP signaling as a possible mechanism. That could inform future preclinical research...
A formulation that increases oral absorption of quercetin and reduces inflammation in animal models could point toward new flavonoid-based therapies for ulcerative colitis, but findings are preclinical.
The study suggests that higher levels of objectively measured moderate-to-vigorous physical activity are associated with lower risk of developing ulcerative colitis, and that people may gain similar associations whether...
The study reports that kaempferol reduced inflammation, fibrosis, and barrier damage in mouse and cell models of colitis — mechanisms directly relevant to IBD progression and symptoms.
People with IBD may be concerned about environmental exposures that could influence inflammation or worsen disease. This review explains why micro- and nanoplastics are biologically plausible contributors but also why...
The study proposes a new immunomodulatory approach—phosphatidylserine liposomes—that reduced inflammation in mouse colitis models and altered monocyte and T-cell responses, which could point toward future therapies for...
The study evaluates whether microbial networks differ between groups (including sexes) in IBD and other diseases using a rigorously tested method; that matters because robust methods are needed before microbiome patterns...
Crohn’s disease prevalence and new diagnoses are rising rapidly in Korea, especially among people in their 20s and 30s; that affects demand for diagnosis, long-term care, and affordable treatment.
The study suggests a mechanism (reduced intestinal oxalate transport) that could make common “healthy” plant foods aggravate intestinal inflammation in some people with Crohn’s or ulcerative colitis, which could affect...
Based on the title and source metadata, this appears to be a clinical trial phase 2 related to Inflammatory bowel disease and Diet and lifestyle. The original article is from http://isrctn.com/.
Researchers planned to study whether patterns in the gut microbiome correlate with clinical diagnoses (including Crohn’s and UC), which could inform future biomarker work. The study is suspended, so no results are...
