Colonoscopy, endoscopy, fecal calprotectin, CRP, imaging, intestinal ultrasound, and monitoring research.
Page 15 of 33 · 1561 articles
Mapping microbes and metabolites directly from different gut regions could reveal location-specific changes linked to IBD activity and help researchers develop better biomarkers or targeted treatments.
Faster, reliable reading of capsule endoscopy videos could shorten diagnostic delays and make small-bowel evaluation easier for people with suspected Crohn’s disease. If AI preserves accuracy while reducing review time,...
If you or your clinician are using upadacitinib for Crohn’s, intestinal ultrasound early in treatment may help predict who will not respond and who is more likely to relapse on maintenance dosing, potentially guiding...
If confirmed, a simple calprotectin test on fistula scrapings could help predict which Crohn’s patients are likely to heal after primary surgical fistula closure and which may need additional therapies, potentially...
Clear, reproducible ultrasound definitions for transmural healing and response could help clinicians track deeper intestinal healing beyond mucosal assessment and allow trials to use consistent imaging endpoints.
The study suggests that air pollutant NO2 may promote a perforin-producing CD8+ T cell response linked to colonic inflammation in UC and highlights CDC25B as a potential mechanistic link—information that could guide...
This study reports that combining an anti-TNF-α drug with vedolizumab helped many children with IBD who failed single-biologic therapy achieve clinical, endoscopic, and histologic improvement. It also notes serious...
Cure8 found this source from Alimentary pharmacology & therapeutics, but the page could not be read reliably yet. It is tagged for Inflammatory bowel disease and Tests and monitoring. Open the original article for the...
This study maps cell types in newly diagnosed pediatric Crohn's and links diagnostic cell patterns to disease severity and anti‑TNF treatment response. That could help predict which children are likely to benefit from...
Ileal pouch disorders are common after IPAA surgery and cause symptoms many patients will experience. Early recognition and initial treatment by primary care can speed symptom relief and identify patients who need...
Proactive monitoring of adalimumab levels could help keep drug concentrations therapeutic and reduce loss of response during maintenance therapy for ulcerative colitis.
People with UC have lower baseline gut microbial diversity and slower recovery after PEG bowel preparation; improving recovery of beneficial microbes could matter for symptom stability and gut health. This study suggests...
A cellular atlas that links diagnostic biopsy cell states to treatment outcomes could help predict which children are likely to have severe or anti‑TNF‑resistant Crohn's disease, informing future research on personalized...
This study maps cell-level signatures in newly diagnosed pediatric Crohn’s and links them to later severity and responses to anti-TNF treatment, which could help predict which children will respond to biologic therapy...
Identifying baseline cellular states that predict disease course or response to anti‑TNF could help researchers develop predictive biomarkers and new therapeutic strategies for pediatric Crohn’s disease.
Accurate recognition and standardized reporting of IBD-associated dysplasia help guide surveillance and surgical decisions because some dysplastic variants are flat, endoscopically invisible, and linked to advanced or...
This narrative review surveys novel biomarkers and therapeutic strategies for adult IBD, topics that could affect diagnosis, monitoring, and future treatment options for people with Crohn's disease or ulcerative colitis.
This registry entry describes a completed Phase 2 study of a new IV drug (tulisokibart) for moderate–severe ulcerative colitis, including safety endpoints and a companion diagnostic — information patients may want when...
This trial tests a novel cell-derived extracellular vesicle therapy (DB-3Q) for people with Crohn’s disease who have not responded to standard advanced therapies. It may offer a different biologic approach if proven safe...
This observational study aims to link nutritional status and the dietary inflammatory potential to IBD activity and to test whether simple blood-derived inflammatory indices can serve as noninvasive markers of disease...
This study looks at how immunomodulators are actually used with biologic drugs in real-world practice when a national reimbursement policy forces biologic interruptions.
If you or someone you care for is not responding to anti‑TNF drugs for ulcerative colitis, this review explains biological reasons why that may happen and points toward research directions that could lead to better tests...
Researchers are investigating circRNAs as potential biomarkers and therapeutic targets in IBD because they may help explain disease mechanisms and lead to better diagnostics or treatments in the future.
Patient-derived intestinal organoids offer a human-relevant platform that could improve understanding of pediatric IBD biology and help predict individual treatment responses — potentially reducing trial-and-error...
Anaemia is a common and impactful complication in children diagnosed with IBD; knowing how often it occurs, which subtypes are most frequent, and its link with disease activity can guide monitoring and management...
Imaging and endoscopy can give different pictures of disease activity in newly diagnosed pediatric Crohn’s disease. That matters because treatment decisions often rely on how active disease appears and where it’s...
Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis and Tests and monitoring. The original article is from Academic Radiology.
Digital health tools could offer more continuous monitoring and self-management support for people with IBD, potentially helping detect flares earlier and improve quality of life. This review collects existing evidence...
The study maps cell-level programs in ileum and colon that associate with failure to respond to biologic therapies, suggesting specific cellular markers and niches that could help explain treatment resistance and guide...
The study identifies distinct fecal bile acid signatures in CRC versus UC that might help develop noninvasive tests to distinguish malignancy from chronic inflammatory disease of the colon.
SLE can affect the gut and sometimes looks like ulcerative colitis, so patients with atypical IBD features or new systemic signs may need immunological testing to avoid misdiagnosis.
The study suggests a common environmental pollutant could worsen intestinal inflammation in experimental colitis and identifies molecular pathways that might mediate that effect, which could be relevant to understanding...
The study provides a more rigorous, leakage-free machine-learning analysis of a major IBD microbiome cohort and proposes reproducible microbial and metabolic pathway candidates that could eventually help IBD diagnosis or...
The findings suggest blood DNA methylation changes may mark UC long before symptoms start; that could eventually enable earlier risk identification or research into preventing progression to symptomatic disease.
People with IBD who don’t respond well to ustekinumab may need alternative options. This study will track how patients fare after switching to guselkumab in routine clinical care and report rates of deep remission at one...
The study explores breath VOCs as a possible noninvasive biomarker for IBD activity, which could offer easier, more acceptable monitoring than colonoscopy or stool tests.
Perianal fistulas are a common, often debilitating complication of Crohn's disease that require accurate imaging to guide medical and surgical care. If TPUS performs well, it could offer a faster, lower-cost,...
Surgery is common in Crohn’s disease and timing may relate to disease severity and long-term outcomes. Understanding factors linked to early surgery helps patients and clinicians weigh risks and expectations after...
Distinguishing acute infectious gastroenteritis from new‑onset IBD can be clinically challenging. Faecal biomarkers that help tell these apart could speed correct diagnosis and treatment and avoid unnecessary...
The study suggests Crohn’s disease is associated with altered brain network organization in regions involved in sensing the body and emotions; anxiety appears to modulate these brain circuits. This could help explain why...
DOTATATE PET/CT can show uptake in non‑neuroendocrine diseases, which may lead to misdiagnosis or unnecessary treatments if imaging findings are not confirmed. People with Crohn's disease or other abdominal pathology who...
Preclinical work identified a plant-root extract fraction that reduced inflammation and improved some gut-barrier and microbiome features in a mouse model of ulcerative colitis, which could guide future research into new...
Improving oral delivery and colon targeting of probiotics could make probiotic therapies more effective for ulcerative colitis by increasing survival through the gut and retention at inflamed sites. If translated to...
Thiopurines are commonly used in IBD (azathioprine, 6-mercaptopurine). This review links these drugs — especially 6-thioguanine — to liver microvascular injury that can lead to portal hypertension, which may present...
Identifying Giardia genotypes linked to more severe symptoms could matter for people with IBD or recurrent intestinal infections because different assemblages may relate to symptom severity and could influence diagnostic...
For people with UC on long-term tofacitinib, this trial provides evidence about the chances of keeping remission after stepping down dose and about safety differences between 10 mg and 5 mg twice daily over 30 months.
Patients with UC who appear healed on endoscopy can still relapse; a biopsy-based model could help separate lower- and higher-risk patients and guide monitoring or research enrollment.
FABP2 is presented as a sensitive biomarker of intestinal mucosal injury and a possible contributor to IBD mechanisms; if validated, it could improve disease monitoring and suggest new therapeutic targets.
