Colonoscopy, endoscopy, fecal calprotectin, CRP, imaging, intestinal ultrasound, and monitoring research.
Page 14 of 33 · 1560 articles
This study reports a non-invasive fluorescence probe that detects a reactive nitrogen species (peroxynitrite) linked to intestinal inflammation and shows signal changes in cells, animal models, and mouse feces — a...
This study provides real‑world data on how long biologic‑experienced UC patients stay on ustekinumab, which helps patients and clinicians set expectations about drug persistence and factors that might influence stopping...
The study suggests that a simple, multidomain functional measure (intrinsic capacity) is linked to later IBD risk and that combining it with genetic risk may better identify people at higher risk—especially for Crohn’s...
If blood bile acid patterns are reproducibly different in IBD and track with disease activity, they could become noninvasive biomarkers to help diagnose IBD or monitor flares. That would be useful for patients and...
Psoriasis and Crohn’s disease share immune pathways that affect treatment choices. Some biologics work across both conditions while others (notably IL-17 inhibitors) may be inappropriate for patients with active IBD.
This study describes a novel colon-targeted microgel delivery system carrying an anti-inflammatory natural compound that, in a mouse model, reduced colitis signs and altered gut bacteria — a potential new strategy for...
This atlas maps when and where regenerative gene programs turn on in the intestine and highlights molecular features (like interferon responses and hypertranscription) that overlap with human Crohn’s disease, so it could...
Diet is a modifiable factor that could influence IBD risk through effects on the gut microbiome and immune pathways.
The study shows malnutrition is common in Crohn’s disease and much more likely during active inflammation, highlighting the need for routine nutritional screening and more than one type of assessment.
This registry study shows many people with IBD in Kazakhstan had clinically active disease at enrollment and identifies factors linked with active UC and CD. It highlights potential gaps in disease control and...
Persistent fatigue is a common disabling symptom in IBD even during remission; a structured adapted physical activity program could offer a non-drug way to improve daily functioning if the trial shows benefit.
People with stricturing Crohn’s disease currently lack effective medical treatments to prevent or reverse intestinal fibrosis; this trial explores a probiotic approach (and trehalose) aimed at stimulating autophagy, a...
Long-term, real-world safety data help patients and clinicians understand risks — especially serious infections — when a newer ulcerative colitis drug is used in routine practice. This registry entry shows Pfizer is...
Researchers can use these human tissue slice cultures to study inflammation and test drugs on a patient’s own biopsy tissue, which could eventually help explain treatment response or resistance in IBD and related...
Both EEN and the Crohn’s disease exclusion diet are used to induce remission in children with Crohn’s disease. Evidence that they perform similarly through 52 weeks may help families and clinicians choose the approach...
Knowing which symptoms and non-invasive biomarkers most strongly associate with UC can help patients and clinicians decide who should be prioritized for diagnostic endoscopy and for monitoring disease activity.
This study builds a large, public single-cell map of the gut in Crohn’s disease that identifies cell types and gene programs linked to inflammation. That can help researchers find new drug targets and explain why some...
Based on the title and source metadata, this appears to be a case report related to Crohn's disease and Procedures and surgery. The original article is from Gastrointestinal endoscopy.
These methods could help researchers and clinicians better identify which treatments are likely to work for which patients by combining trials and EHR data, accounting for multiple outcomes and missing data — relevant to...
If you have Crohn’s disease, upper GI biopsies showing focally enhanced gastritis or focally active inflammation could support a diagnosis of upper GI involvement and are associated with other histologic findings like...
People with IBD already have a higher baseline risk of colorectal cancer. This study finds that having multiple first‑degree relatives with CRC adds the largest absolute additional risk, which could affect how...
If confirmed, molecular or microbial markers found at surgery could help identify Crohn’s patients at higher risk of postoperative endoscopic recurrence and inform closer monitoring or preventative strategies after...
Non-invasive, portable tests that can track inflammation more frequently could help patients and clinicians monitor disease activity between clinic visits and guide treatment decisions without repeated invasive...
The study identifies osteopontin as a stromal-secreted protein elevated in IBD-derived colonic fibroblasts and shows it can restrain epithelial maturation in human colonic organoids, a mechanistic insight that could be...
Food choices can affect Crohn’s symptoms, flares, and nutritional health. A short self-assessment can help you decide whether to change your diet or seek professional nutrition support.
The findings suggest that early biologic and immunomodulator treatment may reduce the need for first surgery in Crohn's disease, which is directly relevant to treatment planning and expectations for people with IBD.
Switching biologics is a frequent and consequential decision in children with IBD; using TDM and a mechanism‑based approach can help choose whether to optimize, switch within class, or change drug class.
Malnutrition was common and much more frequent during active Crohn’s disease in this South Asian cohort, which matters because poor nutritional status affects treatment tolerance, recovery, and quality of life.
The findings show earlier and more frequent use of imaging, endoscopic assessment, anti-TNF therapy, and seton placement for active perianal fistulizing Crohn’s disease over recent years — practices that may affect...
People with IBD are at higher risk for colorectal cancer; identifying stromal genes that track inflammation-driven EMT could help researchers find biomarkers or targets that explain how chronic inflammation promotes...
A blood test (serum REG3α) may help identify people at higher risk of developing complicated Crohn's disease years before diagnosis and predict progression in established disease, which could inform monitoring or early...
Physical activity may be a modifiable factor that could improve fitness, inflammation, symptoms like fatigue, and quality of life in children with IBD. This trial will provide objective, randomized data relevant to...
CAR-Treg and Treg-cell therapies aim to specifically suppress harmful gut inflammation and could offer a new treatment option for people whose IBD does not respond to current drugs. Right now this is early-stage work —...
Finding reliable blood biomarkers for ulcerative colitis activity could make monitoring disease flares easier and less dependent on invasive tests. NGAL and S100A12 rising with active disease suggests they might help...
Based on the title and source metadata, this appears to be a patient education related to Crohn's disease, Inflammatory bowel disease, and Tests and monitoring. The original article is from msn.com.
This FDA drug-label update describes approved uses and safety warnings for tofacitinib, a JAK inhibitor used in immune-mediated diseases including ulcerative colitis. The boxed warnings highlight serious infection and...
The work highlights macrophage metabolic programs and specific genes that may help classify UC molecular subtypes and suggest candidate biomarkers or therapeutic targets related to macrophage-driven inflammation.
The study links a common environmental chemical (BPA) to worse epithelial injury and inflammation in colitis models, highlighting a potential environmental contributor to IBD-relevant epithelial dysfunction and...
PSC — a serious bile-duct disease linked to IBD — was found on MRCP in about 1 in 10 people at IBD diagnosis, often without abnormal liver blood tests. Early radiological detection could affect monitoring and specialist...
The study suggests that anti‑TNF treatment in IBD is associated with weaker and less cross‑reactive antibody and memory B‑cell responses after COVID‑19 booster vaccination, which may reduce durability of protection and...
This is the official FDA label text for dexamethasone, so it clarifies approved uses and gives practical dosing and tapering guidance. It explicitly names "regional enteritis and ulcerative colitis," which matters to...
This label update confirms current FDA prescribing information for sulfasalazine delayed‑release tablets, which many people with ulcerative colitis may be prescribed for induction and maintenance of remission.
This report highlights that Langerhans cell histiocytosis can present with intestinal ulcerations mimicking IBD and may be missed if standard IBD treatments don’t help. Patients with persistent bleeding or nonresponsive...
Vitamin D deficiency is common in people with IBD and this study suggests correcting deficiency may help rebalance immune cells and the microbiome—potentially supporting inflammation control alongside standard...
Protease and serpin activity affect the gut barrier, immunity, and microbial ecology—processes central to IBD. Integrating these pathways could help identify biomarkers or targets that explain why IBD varies between...
Iliopsoas abscess is an uncommon but serious penetrating complication of Crohn’s disease that can present with non-specific symptoms and be missed. The review compiles case-level evidence about presentation, diagnosis,...
People with Crohn’s who have had ileal or ileocolic surgery often worry about needing another operation; this study seeks clinical and biomarker predictors to estimate that risk. Understanding predictors could help...
Mapping microbes and metabolites directly from different gut regions could reveal location-specific changes linked to IBD activity and help researchers develop better biomarkers or targeted treatments.
