Colonoscopy, endoscopy, fecal calprotectin, CRP, imaging, intestinal ultrasound, and monitoring research.
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Older adults (≥60) with IBD are an increasing population worldwide, and IBD-related anemia is rising—this affects screening needs, healthcare planning, and resource allocation. The findings point to widening...
Appendiceal phlegmon and fistulization can produce focal terminal ileal changes that look like Crohn’s disease on imaging and endoscopy; recognizing this can prevent misdiagnosis.
Patients who present with new radiologic terminal ileitis sometimes develop Crohn’s disease. Identifying simple blood and imaging markers that predict who is at higher risk could help prioritize follow-up or specialist...
This study suggests that a confirmed Campylobacter stool infection in people with IBD was followed by higher rates of flare and need for treatment escalation within 12 months, so infected patients might need closer...
Patients cared for in accredited IBD units reported better experience and higher satisfaction in this study, which suggests that accreditation may improve patient-centred aspects of care even if self-reported disease...
A validated Spanish IBD-Disk gives Spanish-speaking patients and clinicians a brief, validated tool to measure disability and global health in IBD, supporting consistent monitoring and research across Spanish-speaking...
Patients with moderate-to-severe Crohn's disease who do not respond to anti-TNF drugs have limited options. This study suggests combining ustekinumab with upadacitinib may improve endoscopic healing versus either drug...
Trends in treatments for children with IBD can affect hospitalization and surgical needs. Noting rising use of biologics (infliximab) alongside fewer hospitalizations may be important for families and clinicians tracking...
Better endoscopic classification of flat-type dysplasia could improve surveillance accuracy for people with long-standing ulcerative colitis, helping identify lesions that need biopsy or more urgent management.
If a panenteric capsule can replace colonoscopy plus small-bowel imaging for initial diagnosis, it could offer a less invasive, single-test pathway for many people suspected of having Crohn's disease. That may reduce the...
This trial tests an oral live biotherapeutic (MH002) aimed at restoring a healthier gut microbiome in people with mild-to-moderate ulcerative colitis. If effective and safe, it would offer a non-immunosuppressive,...
Malnutrition is common and can worsen outcomes in IBD; this case shows use of combined enteral and parenteral nutritional support for severe malnutrition in newly diagnosed Crohn’s disease, including perioperative...
The findings highlight that older adults are less likely to be prescribed advanced IBD therapies, which could reflect prescribing patterns, comorbidities, insurance factors, or access issues relevant to treatment...
Identifies a molecule (CCL3) linked to more severe inflammation in IBD tissues, which could help researchers develop new biomarkers or treatments targeting immune-cell recruitment and polarization.
The study connects a bothersome UC symptom (bowel urgency) to intestinal ultrasound signs of transmural inflammation, suggesting ultrasound might help explain and track symptom-related inflammation without relying solely...
SRCEUS may offer higher-resolution, noninvasive assessment of intestinal microvascular changes that correspond to Crohn disease activity, which could improve monitoring and reduce reliance on invasive tests.
Based on the title and source metadata, this appears to be an opinion or commentary related to Crohn's disease, Inflammatory bowel disease, and Tests and monitoring. The original article is from Radiology.
Identifies a stromal-cell subset marked by TIMP1 that may play a role in UC pathogenesis and might serve as a candidate biomarker or therapeutic target; useful for researchers and clinicians following emerging...
Cure8 found this source from auntminnie.com, but the page could not be read reliably yet. It is tagged for Crohn's disease, Inflammatory bowel disease, and Tests and monitoring. Open the original article for the full...
Better automated scoring tools for endoscopic images could reduce variability between human reviewers and help standardize assessments of ulcerative colitis severity used for treatment decisions and monitoring.
Based on the title and source metadata, this appears to be a patient education related to Tests and monitoring. The original article is from msn.com.
The study reports anti-inflammatory and antioxidant effects of a new andrographolide formulation in a macrophage model relevant to ulcerative colitis, highlighting a potential early-stage therapeutic lead that may...
Based on the title and source metadata, this appears to be an observational study related to Tests and monitoring. The original article is from hmpgloballearningnetwork.com.
This trial tests standardized encapsulated fecal microbiota products as a microbiome-directed therapy for active Crohn’s disease, focusing on whether donor microbes engraft in the ileum and colon and whether that relates...
C. difficile can cause or complicate diarrhoea in children with IBD, so understanding test positivity in this group helps clinicians interpret results and decide when to investigate or treat. The study suggests...
Juvenile colorectal polyps in children show strong type 2 inflammatory and epithelial-remodeling programs that could explain links with allergic sensitization and suggest biomarkers and pathways relevant to mucosal...
Malnutrition and growth failure at diagnosis are common in children with IBD—especially Crohn’s—and can indicate higher inflammatory burden. Monitoring and addressing nutrition and growth is important because most...
This review highlights shared biomarkers and mechanisms between early Crohn's disease and post-operative recurrence, which could improve prediction and lead to preventive strategies for recurrence after surgery.
The paper presents a proof-of-concept immune-based assay to match donors and recipients for FMT in IBD, which could help explain variable FMT outcomes and improve donor selection if validated.
The study suggests a hidden, early molecular defect that leaves intestinal cells primed to die even during clinical remission, which could help explain why flares recur. Measuring these molecular signals might eventually...
Dysplasia detection during colonoscopy is central to preventing colorectal cancer in people with IBD. AI tools could help, but current models often fail in inflamed or IBD-specific settings, so this review outlines...
Nurse-led, protocolized care can make delivery of complex biologic and small-molecule IBD treatments safer and more consistent.
If pre‑treatment biopsy features predict response to ustekinumab, clinicians might better select which UC patients are likely to benefit, potentially avoiding ineffective therapy for some and speeding effective treatment...
The study provides real-world data on ozanimod effectiveness, safety, and how prior biologic exposure (notably vedolizumab) may affect treatment persistence—information relevant for treatment planning in UC.
This mouse study connects fat malabsorption, increased gut permeability, microbiome shifts, and reduced oxalate transport to higher oxalate absorption and kidney injury—mechanisms relevant to enteric hyperoxaluria seen...
The work links climate and sociodemographic context to IBD burden in tropical regions, which can influence diagnostic recognition, resource needs, and research priorities for communities where IBD is rising.
Automated, quantitative analysis of pathology slides could reduce variability in histological scoring and help track histological healing — a growing therapeutic target in ulcerative colitis.
Patients with CGD can develop an IBD-like condition that is hard to treat because many immunosuppressive drugs raise infection risk. This trial suggests thalidomide may reduce intestinal inflammation in CGD-IBD without...
This study links genetic variation in fatty-acid–desaturase genes with membrane PUFA profiles and inflammatory markers in Crohn’s disease. If replicated, erythrocyte desaturase indices could become integrative biomarkers...
Antibiotic use patterns in hospitalized IBD patients affect infection risks, microbiome impact, resistance pressure, length of stay, and costs. Shifting focus from simple exposure counts to intensity and escalation can...
Researchers found that nearly all people with UC have high-titer autoantibodies to the epithelial integrin αvβ6 that can precede disease and associate with worse outcomes. Understanding whether and how these antibodies...
Knowing biomarkers that predict who will respond to IL23 p19 inhibitors could help people with IBD avoid trial-and-error therapy choices. Understanding whether increasing risankizumab dosing after loss of response...
This project aims to understand how gut-adapted eosinophils support immune homeostasis or drive pathology in conditions that include IBD and eosinophilic GI disorders, with the goal of enabling more precise...
Pregnant people with IBD or other autoimmune diseases often face tough choices about continuing biologics or JAK inhibitors. CARE-HP aims to produce broader, disease-specific evidence to help patients and clinicians...
A quantitative, biopsy-based measure of collagen architecture could help study intestinal fibrosis, which underlies stricture formation in Crohn’s disease. Feasibility data support further validation work that may lead...
Oral and upper-GI involvement in Crohn's can be missed and may change how disease is diagnosed and managed. A focused review helps clinicians and researchers spot gaps in diagnostics and treatment research.
A new single-cell analysis tool may help researchers and clinicians studying IBD (here shown for ulcerative colitis) to detect and interpret changes in cell–cell signaling that accompany disease or treatment response.
People with IBD often need biologic therapy during their reproductive years. This review compiles comparative evidence about pregnancy risks with different biologics to inform decisions about continuing or switching...
