Tests and monitoring

The review lays out a multidimensional precision-care model that could help make IBD treatment more personalized, reduce unnecessary continuous medication, and use biomarker and technology-driven adjustments to manage...

The study suggests that measuring fat-free mass (FFMI) may reveal nutritional recovery after an IBD flare that BMI alone misses, which matters for identifying and treating malnutrition in IBD.

Arthritis is a common and meaningful extraintestinal problem for people with IBD; understanding diagnosis and treatment options can help patients and clinicians seek appropriate multidisciplinary care.

This large, population-level analysis summarizes long-term global trends in IBD burden and shows rising incidence and persistent geographic and socio-demographic inequalities. Patients and clinicians may see why...

The work searches for shared blood-based gene signatures and biomarkers across HLA-B27–linked diseases (including Crohn’s disease and ulcerative colitis), which could point to common mechanisms or cross-disease...

Clostridium difficile infection is an important and potentially serious complication in ulcerative colitis. A blood‑marker–based risk model could help identify higher‑risk patients noninvasively so clinicians can...

Researchers identified molecular features of a proposed “ferro‑aging” state in UC and nominated CHST15 and MSN as biomarkers, which could help understand disease biology and point to new experimental targets for therapy...

This study reports a new engineered platform that can catalytically degrade TNF‑α, the same inflammatory cytokine targeted by several IBD therapies. If translated to humans, it could offer longer‑lasting mucosal...

A systematic review finds risankizumab (an IL-23 inhibitor) effective and generally well tolerated for moderate-to-severe Crohn's disease and ulcerative colitis, including in patients who failed prior biologics. This...

Distinguishing UC from Crohn’s colitis can be challenging but affects long-term management and surveillance. A histologic feature—homogeneity versus heterogeneity of epithelial lesions across biopsies—might help improve...

Corticosteroid use during IBD treatment periods was associated with higher rates of serious infections across drug classes and age groups, which may affect decisions about steroid use and infection-prevention planning.

The review summarizes how extracellular vesicles (EVs) shape immune responses and barrier repair in the gut and discusses their potential as accessible biomarkers and as vehicles for precise IBD therapies — topics that...

A wearable sensor that reliably measures inflammation markers (CRP and calprotectin) from sweat could make inflammation monitoring less invasive and more frequent for people with IBD, potentially helping detect flares...

People with IBD have higher risk of several GI and hepatobiliary cancers; imaging is an important complement to endoscopic surveillance for detecting cancers that may be transmural or outside endoscopic reach.

This study tests a common clinical question: whether increasing vedolizumab frequency helps patients who show no endoscopic response after 6 months. The results suggest intensification raised drug levels but did not...

This registry will track long-term safety and clinical outcomes in children with IBD, with a focus on infliximab (an anti‑TNF biologic) versus non‑biologic therapies. Long follow-up could help identify uncommon or late...

Phase 3 testing of guselkumab (an IL-23–targeting biologic) in moderately to severely active ulcerative colitis could expand treatment options if the trial meets its endpoints and shows an acceptable safety profile. The...

AI tools are being tailored to IBD care; this study suggests supervised fine-tuned LLMs may help with patient communication and workflow but currently lack reliable diagnostic accuracy. Patients and clinicians should...

Perianal fistulas are a common and often challenging complication of Crohn’s disease. This surgical series provides outcome data on draining seton treatment that may help patients and clinicians understand typical...

This case shows that upadacitinib, a JAK inhibitor used for refractory IBD, can cause severe anemia in rare cases but that dose reduction (rather than permanent discontinuation) may reversibly restore blood counts while...

People with IBD and their clinicians may want to be aware of possible higher rates of some non-gastrointestinal cancers (thyroid, kidney, prostate) and of factors linked to higher risk such as long-term steroid use,...

The study identifies abnormal epithelial cell–death signaling that persists despite current therapies and may help explain why many people with IBD relapse. If validated, these pathways could point to new biomarkers or...

If you have overweight or obesity, this study suggests measurable blood proteins linked to inflammation may be associated with higher future risk of ulcerative colitis. Identifying such markers could help research on...

Researchers working on IBD molecular mechanisms or biomarker discovery may find this AI-driven approach useful because it can detect temporal gene-expression patterns and suggest pathways linked to treatment response...

This single case shows that bedside ultrasound can detect serious abdominal problems (intussusception, ischemia) early in people with IBD even when initial vitals and labs look normal.

This trial could show whether intra-operative ultrasound can be used reliably to choose the proximal resection margin during ileocecal resection for terminal ileal Crohn’s disease—information that might affect surgical...

People with IBD and other immune conditions may develop weaker or lower‑quality antibody responses after COVID‑19 vaccination compared with healthy people, and transplant recipients showed the largest impairments. That...

Measures used in trials and care often miss what patients value most — daily function and quality of life. Learning from IBD and RA could lead to asthma outcome measures and trials that reflect patient priorities, which...

Pathology after fecal diversion can look like active IBD, which affects diagnosis and management of the diverted rectum. This study helps clarify when changes likely reflect diversion alone versus persistent inflammatory...

A strategic, pediatric-focused research agenda helps target studies where children with IBD and related conditions most need better diagnostics, biomarkers, and treatments. Prioritizing multi-center registries and...

The paper proposes ISG20 as a shared molecular link between RA and IBD, which could help explain why the two diseases co-occur and point to a candidate biomarker for identifying patients at risk of both conditions.

This study identifies conserved, gut-enriched genes (colonization factors) and shows their repertoires are remodeled in IBD, highlighting functional microbiome changes that could inform future biomarkers or...

Diet quality was linked to gut microbiome features and exploratory differences in inflammatory markers and symptoms in adults with Crohn disease from Puerto Rico; understanding these links may help tailor dietary...

Tools that reliably measure self-care self-efficacy can help clinicians identify IBD patients who may benefit from extra self-management support. A brief, validated 10-item scale is practical for busy clinics and...

Because having a sibling with Crohn's disease during childhood was linked to substantially higher risk of developing Crohn's later, and the study points to early-life microbiome differences and elevated faecal...

Achieving histologic or biochemical remission in addition to clinical and endoscopic remission was associated with substantially lower relapse risk in ulcerative colitis across multiple follow-up intervals, suggesting...

Non-invasive, inexpensive blood-derived ratios could offer easier, more frequent assessment of IBD activity than repeat endoscopy. This study evaluates several such ratios (CAR, PAR, NLR, FAR, Hb/CRP) against clinical...

Perianal fistulizing Crohn’s disease is difficult to treat and many patients don’t respond to available medical and surgical options. This trial tests an existing wound‑healing therapy (HBOT) in a formal controlled...

This trial tests whether a seaweed-derived fucoidan given with standard 5-ASA therapy can change biomarkers linked to mucosal healing (fecal calprotectin, fecal short-chain fatty acids) and stool consistency in people...

Cure8 could only read part of this source from Radiopaedia.org, so this card uses cautious topic tags instead of a full summary. It is tagged for Ulcerative colitis, Inflammatory bowel disease, and Tests and monitoring.

Based on the title and source metadata, this appears to be a clinical study related to Crohn's disease, Fecal calprotectin, and Fistula. The original article is from Colorectal Disease.

Research linking ETBF to intestinal inflammation and colorectal cancer suggests better detection and targeted therapies for this microbe could eventually affect IBD management and cancer risk assessment.

Nutrition during acute severe ulcerative colitis matters because patients can become rapidly nutritionally fragile, and appropriate feeding and monitoring can affect recovery, complications, and readiness for surgery....

Non-invasive biomarkers can help detect and monitor IBD activity, distinguish IBD from other GI conditions, and potentially predict relapse—tools that may reduce need for invasive tests.

Folate deficiency can cause anemia and other health problems; knowing how common it is in people with celiac disease can help guide screening and supplement decisions. The link with coexisting ulcerative colitis may be...

Patients diagnosed with IBD during or shortly after emergency hospital care had substantially worse 1-year outcomes in this large, population-based analysis — highlighting that late or emergency presentation is linked to...

Prednisone is commonly used short-term in IBD flares; an FDA label update clarifies approved uses and dosing considerations that affect how clinicians prescribe it and how patients should take and stop the drug.

Delays in diagnosing IBD are common and can raise the risk of complications, so understanding when to push for testing matters. The article explains tests and differences between IBS and IBD to help people know when to...