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Genetic risk factor for Crohn's disease influences natural microbiome changes during pregnancy, mouse study finds
medicalxpress.com

Genetic risk factor for Crohn's disease influences natural microbiome changes during pregnancy, mouse study finds

This study suggests a Crohn's genetic risk factor can change pregnancy-related gut microbiome shifts and increase inflammatory signals in mice — which could help researchers look for microbial biomarkers that predict...

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The SERPINB4 gene mutation identified in twin patients with Crohn's disease impaires the ... - Nature
nature.com

The SERPINB4 gene mutation identified in twin patients with Crohn's disease impaires the ... - Nature

This study links a specific SERPINB4 gene mutation to impaired intestinal epithelial cell function in twins with Crohn’s disease, which could help explain how rare genetic variants contribute to disease in some patients.

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