Condition

Crohn's disease

Crohn's disease news across medications, symptoms, tests, procedures, complications, research, access, and daily life.

Page 7 of 53 · 2514 articles

Association between Crohn’s disease and pulmonary nodule patterns: an inverse probability-weighted analysis of real-world data
Clinical and Translational Gastroenterology

Association between Crohn’s disease and pulmonary nodule patterns: an inverse probability-weighted analysis of real-world data

The study suggests pulmonary nodules are more common in people with Crohn’s disease and that age and certain medications (not disease phenotype) may better predict nodule burden — information that could influence how...

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Budget impact analysis of subcutaneous infliximab (CT-P13 SC) for treating autoimmune diseases in Jordan
Cost Effectiveness and Resource Allocation

Budget impact analysis of subcutaneous infliximab (CT-P13 SC) for treating autoimmune diseases in Jordan

Modeled cost savings and fewer hospital visits could affect access to infliximab for people with Crohn’s disease and other autoimmune conditions in Jordan, potentially increasing the number of patients who can be treated...

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Few-shot learning for expert consensus severity stratification in newly diagnosed crohn’s disease
Journal of Translational Medicine

Few-shot learning for expert consensus severity stratification in newly diagnosed crohn’s disease

Standardized, automated severity stratification at diagnosis could help guide early treatment planning and comparability across centers. An AI approach that approximates expert consensus may reduce variability in initial...

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PD-1 and PD-L1 Expression in Inflammatory Bowel Disease: A Paired Immunohistochemical Study
Biomedicines

PD-1 and PD-L1 Expression in Inflammatory Bowel Disease: A Paired Immunohistochemical Study

This study links higher mucosal PD-L1 expression to active IBD and routine disease activity measures, suggesting the PD-1/PD-L1 immune checkpoint may be involved in intestinal inflammation and could be a biomarker or...

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Distinct Microbiological Profile of Intra-Abdominal Abscesses in Crohn's Disease: A Multicenter Cohort Study from GETECCU.
Gastroenterologia y hepatologia

Distinct Microbiological Profile of Intra-Abdominal Abscesses in Crohn's Disease: A Multicenter Cohort Study from GETECCU.

Microbiological differences in Crohn’s-related abscesses could affect empirical antibiotic choices and highlight the importance of culture-directed therapy, especially in patients on immunosuppression who showed higher...

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Adherence to advanced therapies in inflammatory bowel diseases: Real-world rates and predictors of non-adherence.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

Adherence to advanced therapies in inflammatory bowel diseases: Real-world rates and predictors of non-adherence.

Adherence affects how well advanced IBD treatments work. Knowing which drug forms and patient factors link to missed doses can help patients and clinicians plan support strategies.

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Prevalence of Enteric Hyperoxaluria in Crohn's Disease, Cystic Fibrosis, and After Bariatric Surgery: A Systematic Review
Europe PMC

Prevalence of Enteric Hyperoxaluria in Crohn's Disease, Cystic Fibrosis, and After Bariatric Surgery: A Systematic Review

Enteric hyperoxaluria increases risk of calcium oxalate kidney stones and kidney injury. Knowing how common EH is in Crohn's disease and after bariatric surgery helps identify who might benefit from screening and...

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Elective combined surgical management of concurrent gastrocolic and duodenocolic fistulae in longstanding Crohn's disease.
Clinical journal of gastroenterology

Elective combined surgical management of concurrent gastrocolic and duodenocolic fistulae in longstanding Crohn's disease.

Internal fistulae can be clinically silent yet serious in long-standing Crohn's disease. Early cross-sectional imaging detected rare gastrocolic and duodenocolic fistulae in this patient, and elective combined surgery...

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Plasma lipopolysaccharide-binding protein (LBP), a proxy for intestinal permeability, relates to clinicopathological and immunological disease activity in inflammatory bowel disease patients at diagnosis and during disease course.
Journal of Crohn's & colitis

Plasma lipopolysaccharide-binding protein (LBP), a proxy for intestinal permeability, relates to clinicopathological and immunological disease activity in inflammatory bowel disease patients at diagnosis and during disease course.

A simple blood marker (LBP) that reflects bacterial exposure across the gut barrier was linked to disease severity and immune activity at diagnosis and during follow-up—especially in ulcerative colitis—so it might help...

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Specialized macrophages link gut lymphoid follicles to Crohn’s disease granulomas
Springer Science and Business Media LLC

Specialized macrophages link gut lymphoid follicles to Crohn’s disease granulomas

The study helps explain how granulomas—linked to more severe Crohn’s disease—might form by repurposing lymphoid follicle macrophages, pointing to cellular programs and signals that could be relevant for future biomarkers...

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Study of Efficacy and Adherence to Subcutaneous vs. Intravenous Vedolizumab in Patients With Inflammatory Bowel Disease Using a Novel Remote MONITORing Intervention
ClinicalTrials.gov

Study of Efficacy and Adherence to Subcutaneous vs. Intravenous Vedolizumab in Patients With Inflammatory Bowel Disease Using a Novel Remote MONITORing Intervention

Adherence to biologic therapy can affect how well treatment controls IBD; understanding whether self-administered subcutaneous vedolizumab has different adherence than IV infusion could influence treatment choices and...

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Changing Prescription Patterns in Pharmacologically Treated Patients with Newly Diagnosed Inflammatory Bowel Disease in German Gastroenterology Practices: A Real-World Study, 2015–2024
Pharmaceuticals

Changing Prescription Patterns in Pharmacologically Treated Patients with Newly Diagnosed Inflammatory Bowel Disease in German Gastroenterology Practices: A Real-World Study, 2015–2024

The study documents shifting real-world prescribing for newly diagnosed IBD in Germany, with more biologic use and less mesalazine/thiopurine in recent years — changes that could affect treatment expectations and access.

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Differential long-term efficacy of biologic and small-molecule therapies by disease location in moderate-to-severe luminal Crohn's disease: a systematic review and network meta-analysis.
Inflammatory bowel diseases

Differential long-term efficacy of biologic and small-molecule therapies by disease location in moderate-to-severe luminal Crohn's disease: a systematic review and network meta-analysis.

The analysis suggests that some biologic and small-molecule therapies work differently depending on whether Crohn's disease affects the ileum, colon, or both — information that could help tailor long-term treatment...

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A Giant Intra-Abdominal Plasmablastic Neoplasm Favoring Lymphoma Mimicking an Exacerbation of Severe Fistulizing Crohn's Disease: A Case Report.
The American journal of case reports

A Giant Intra-Abdominal Plasmablastic Neoplasm Favoring Lymphoma Mimicking an Exacerbation of Severe Fistulizing Crohn's Disease: A Case Report.

A rapidly growing abdominal mass or unexplained systemic decline in someone with Crohn's disease may represent a rare malignancy (plasmablastic neoplasm) rather than infection or a disease flare; prompt biopsy is...

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Contemporary outcomes and restorative pathways following colectomy for inflammatory bowel disease: a tertiary centre cohort from Aotearoa New Zealand.
The New Zealand medical journal

Contemporary outcomes and restorative pathways following colectomy for inflammatory bowel disease: a tertiary centre cohort from Aotearoa New Zealand.

This study reports real-world short-term outcomes after colectomy for IBD at a tertiary New Zealand centre, including complication rates and how often restorative surgery (ileal pouch) was later performed—information...

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Agomab to Present STENOVA Open-Label Extension Data of Ontunisertib at UEG Week ...

Patients with fibrostenosing Crohn’s disease face progressive strictures and limited targeted treatments; data from STENOVA’s OLE and the planned NOV‑ERA trial could advance therapies that target both inflammation and...

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Faecal urgency in Crohn's disease: associations with disease location and activity, psychobiological burden and adverse outcomes.
Revista espanola de enfermedades digestivas

Faecal urgency in Crohn's disease: associations with disease location and activity, psychobiological burden and adverse outcomes.

Faecal urgency is a frequent, disabling symptom in Crohn's disease that was common in this cohort and tied to poorer quality of life, mental-health burden, and more healthcare use over one year.

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Association between Crohn's disease and pulmonary nodule patterns: an inverse probability-weighted analysis of real-world data.
Clinical and translational gastroenterology

Association between Crohn's disease and pulmonary nodule patterns: an inverse probability-weighted analysis of real-world data.

Pulmonary nodules appear more frequently in people with Crohn’s disease and have distinct patterns over time. Knowing which factors predict nodule burden can help clinicians prioritize monitoring and interpret chest...

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The burden of inflammatory bowel disease in Asia (1990-2023) and projections to 2050: A comprehensive analysis of the 2023 global burden of disease study.
PloS one

The burden of inflammatory bowel disease in Asia (1990-2023) and projections to 2050: A comprehensive analysis of the 2023 global burden of disease study.

Rising IBD incidence and prevalence in Asia mean more people will need long-term care, specialist services, and health-system planning. Understanding regional trends helps patients and policymakers anticipate resource...

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