Crohn's disease

Perianal fistulizing Crohn's often causes significant symptoms and requires both medical and surgical approaches. Newer biologics and JAK inhibitors expand treatment options and guidelines increasingly support earlier...

Extraintestinal problems are common in IBD and can cause significant symptoms and treatment needs beyond the bowel. Knowing their frequency helps patients and clinicians prioritize screening and multidisciplinary care.

A platform trial could evaluate multiple advanced therapies and combinations more efficiently, which matters for people with refractory Crohn's disease who have already tried several advanced treatments.

People with IBD often look for safe complementary therapies. Preclinical studies of mangrove extracts suggest possible anti-inflammatory and gut-protective effects worth further research, but they are not proven...

Digital momentary symptom and food-tracking could help people with IBS or IBD-IBS identify personal triggers and tailor lifestyle or treatment choices, potentially reducing abdominal pain and improving quality of life.

Cure8 found this source from health.usnews.com, but the page could not be read reliably yet. It is tagged for Crohn's disease, Inflammatory bowel disease, and Symptoms and flares. Open the original article for the full...

Based on the title and source metadata, this appears to be a case report related to Crohn's disease, Perforation, and Procedures and surgery. The original article is from Internal medicine journal.

People with IBD often have sleep problems and ongoing inflammation; melatonin could help both sleep and clinical disease activity, which may improve quality of life. The review suggests potential benefit but is not...

If true, the tripartite circuit model helps explain why some patients respond to therapies that target one pathway while others do not — because other nodes in the loop may sustain disease.

Based on the title and source metadata, this appears to be a case report related to Crohn's disease, Inflammatory bowel disease, and Pain. The original article is from Gut.

Identifying people at very early, preclinical stages of Crohn’s disease could allow enrollment in prevention trials and earlier intervention. Faecal calprotectin may help select higher‑risk first‑degree relatives for...

This study gives real-world comparative data on two biologic options (vedolizumab vs anti-TNFα) used early in the treatment course for Crohn’s disease, which may help patients and clinicians weigh effectiveness and...

The study suggests habitual diet that supports gut microbes may modestly lower the chance of developing IBD, especially ulcerative colitis, and links dietary patterns to blood protein changes tied to immune and...

The paper points to S100A8 as a potential link between immune-cell-driven inflammation and mitochondrial stress in Crohn’s disease, which could help researchers explore new biomarkers or targets for study.

The study connects microbiome disruptions to new food intolerances in people with IBD in remission, which may explain persistent food-related symptoms despite controlled inflammation and could point to microbiome-based...

Based on the title and source metadata, this appears to be a clinical study related to Crohn's disease, Inflammatory bowel disease, and Ustekinumab. The original article is from The American journal of gastroenterology.

First-person accounts of Crohn's or colitis can help others recognize severe symptoms, the emotional toll of chronic gut disease, and that surgery can be part of a pathway to symptom relief for some people.

Based on the title and source metadata, this appears to be a case report related to Crohn's disease, Inflammatory bowel disease, and Medications. The original article is from Gastroenterology report.

This preclinical study suggests raising mesaconate in the gut can reduce inflammation in mouse models of Crohn’s disease, using either an engineered probiotic or a zinc–mesaconate formulation—approaches that could...

Children with newly diagnosed IBD are increasingly started on advanced therapies early after diagnosis and are receiving fewer corticosteroids.

Engineered extracellular vesicles are an emerging, targeted therapy approach that could someday improve immune control, mucosal healing, and drug delivery in IBD and reduce colitis-associated cancer risk. The review...

Relatives of people with IBD are at higher risk; this study aims to identify early markers or behaviors that predict who develops IBD so prevention or earlier diagnosis might become possible.

Based on the title and source metadata, this appears to be a systematic review or meta analysis related to Crohn's disease, Inflammatory bowel disease, and Microbiome. The original article is from Immunity, inflammation...

Immunosuppressed patients with refractory or atypical Crohn’s symptoms may rarely have intestinal Kaposi sarcoma, which can change management. Recognizing this possibility could alter the need for surgery versus systemic...

Launches of adalimumab and ustekinumab could expand local access to two widely used biologic treatments for Crohn’s disease and ulcerative colitis. Wider availability may affect treatment options and logistics for people...

Patients and clinicians are often looking for objective, noninvasive ways to monitor IBD activity. This study suggests a simple nailfold capillary measure may reflect disease activity and add information to CRP, which...

This review summarises the rapidly changing drug landscape for Crohn’s disease and ulcerative colitis, including newly approved biologics and small molecules and several emerging therapies that may affect future...

This study describes use of upadacitinib for children and young adults with highly refractory IBD and reports that most patients stayed on therapy at 1 year; a small subgroup treated with combined upadacitinib and...

Transmural healing on CT enterography was associated with fewer hospitalizations over long follow-up, which could matter for long-term disease management and monitoring strategies in Crohn’s disease.

Accurate, radiation-free imaging at the point of care can speed diagnosis and management of strictures, abscesses, and fistulas in Crohn’s disease. Improved ultrasound techniques may help determine who needs surgery or...

Based on the title and source metadata, this appears to be a case report related to Crohn's disease, Inflammatory bowel disease, and Ustekinumab. The original article is from Intestinal research.

Small-bowel capsule and balloon-assisted endoscopy are increasingly used for Crohn’s disease; this large real-world study suggests adverse events after SBCE are uncommon and may be less frequent when a patency capsule is...

Perianal fistulas are common and burdensome in Crohn’s disease; this large multicenter Korean study quantifies high rates of complex fistulas, frequent recurrence, and suggests biologic therapy is associated with fewer...

Cure8 could only read part of this source from Intestinal Research, so this card uses cautious topic tags instead of a full summary. It is tagged for Ulcerative colitis, Crohn's disease, and Inflammatory bowel disease.

Cure8 found this source from broadwayworld.com, but the page could not be read reliably yet. It is tagged for Inflammatory bowel disease, Crohn's disease, and Community and awareness. Open the original article for the...

Diet and simple recipes are practical tools many people with IBD use to manage symptoms, maintain nutrition, and feel better day-to-day. Content from the Crohn’s & Colitis Foundation is directly targeted to people...

The study links T cell metabolism and epigenetics to inflammation in IBD, highlighting GSK3β as a possible drug target. That could guide future therapies aimed at dampening pathogenic T cells in Crohn’s disease.

Based on the title and source metadata, this appears to be a case report related to Crohn's disease and Procedures and surgery. The original article is from Clinical case reports.

Based on the title and source metadata, this appears to be a systematic review or meta analysis related to Inflammatory bowel disease, Crohn's disease, and Biosimilars. The original article is from Arquivos de...

Based on the title and source metadata, this appears to be a clinical study related to Crohn's disease, Inflammatory bowel disease, and Fistula. The original article is from Journal of ultrasound in medicine : official...

Berries are a familiar, dietary source of anti-inflammatory bioactive compounds that might help reduce intestinal inflammation and improve biomarkers relevant to IBD. Patients often seek safe, complementary strategies...

Based on the title and source metadata, this appears to be a patient education related to Crohn's disease, Inflammatory bowel disease, and Medications. The original article is from hmpgloballearningnetwork.com.

Cure8 found this source from crohnscolitisfoundation.org, but the page could not be read reliably yet. It is tagged for Inflammatory bowel disease, Crohn's disease, and Community and awareness. Open the original article...

If oxalate in certain plant foods can irritate inflamed intestines or be less well absorbed in IBD, eating large amounts could worsen symptoms for some patients. Awareness can help people track triggers rather than...

For people with Crohn’s disease, this study suggests that biologic drugs reduce inflammation in both proximal and distal small bowel to a similar degree, as measured by capsule endoscopy.

Based on the title and source metadata, this appears to be a case report related to Crohn's disease, Inflammatory bowel disease, and Infliximab. The original article is from Journal of Medical Case Reports.

Postoperative pain control choices after ileocecectomy could affect Crohn's flare risk and opioid exposure. A pediatric center-level analysis found no association between ketorolac and flares and suggested reduced opioid...

Based on the title and source metadata, this appears to be a clinical study related to Crohn's disease, Inflammatory bowel disease, and Strictureplasty. The original article is from Surgical Endoscopy.