Crohn's disease

This project explores whether common environmental chemicals (PFAS) might change biological processes years before IBD appears, which could help explain some cases of Crohn’s disease and ulcerative colitis and point...

Persistent bowel symptoms can signal a range of conditions, including rare cancers; prompt evaluation helps ensure appropriate diagnosis and treatment. The story highlights symptom overlap between Crohn’s disease and...

People with Crohn’s disease may see emerging interest in traditional Chinese medicine as a multi-target approach that could complement standard treatments and affect immune pathways, the gut barrier, and the microbiome.

Vitamin D deficiency is common in people with IBD and can affect bone health and possibly immune function.

People with IBD and RA often try dietary changes to manage symptoms. This trial is testing two very low-carbohydrate approaches to see if they affect symptoms, quality of life, and inflammation, and whether they are...

The study describes real-world use of a treat-to-target approach in adults with Crohn's disease and ulcerative colitis, which may influence how clinicians monitor disease and adjust therapy in routine care.

Eating out can be challenging for people with Crohn's disease because fat content and daily symptom variability affect tolerance. Practical strategies from someone with long-term experience can help other patients...

The study suggests IBD patients can fall into two distinct gut-microbe/metabolite types that align with differences in disease severity and mental-health scores, which could help explain why patients with the same...

Crohn's is becoming more common among younger Americans and long-term uncontrolled inflammation raises colorectal cancer risk. Understanding possible lifestyle and medical factors can help patients and clinicians focus...

Stories from people living with Crohn’s and another autoimmune condition show how symptoms, testing, treatments and daily planning can intersect — and may help others feel less alone and better prepared for practical...

This project explores how CD74 in intestinal stem cells and Paneth cells helps control mucosal immune responses and epithelial repair — processes directly relevant to IBD pathogenesis and recovery.

If shorter, non-contrast MRE protocols can reliably show Crohn’s activity and strictures, patients could have faster scans with less gadolinium exposure. But if ulceration or penetrating disease is suspected,...

The study suggests adding a structured 16-week exclusive enteral nutrition plan to ustekinumab treatment may improve short- and medium-term clinical and endoscopic outcomes for adults with moderate-to-severe Crohn’s...

Links between GWAS risk loci and the specific cell types where those loci may act can focus laboratory experiments and eventually help identify causal genes or pathways relevant to Crohn’s disease.

Many people with IBD use over-the-counter pain relievers without realizing they can irritate the gut. This article explains when ibuprofen or naproxen might raise risks for people with Crohn’s disease or ulcerative...

The review compiles trial and real-world safety data for upadacitinib in IBD and highlights monitoring needs and infection risks (notably herpes zoster), which are directly relevant when choosing or managing JAK...

Early, easily available blood markers that predict mucosal healing could help clinicians decide sooner whether a new or intensified therapy is working, potentially reducing prolonged ineffective treatment and guiding...

Researchers are testing a new swallowable thermal capsule that could eventually help detect temperature changes from GI inflammation. For people with Crohn’s disease or IBD, a safe, noninvasive way to sense inflammatory...

A minimally invasive probe that measures intestinal potential difference in real time could provide a localized, objective way to study gut barrier function—an important feature in Crohn’s disease and other IBDs....

People with Crohn’s disease who rely on local specialty pharmacies or critical access hospitals could be indirectly affected by 340B policy: pharmacies may lose money dispensing biologics that carry orphan designations...

Based on the title and source metadata, this appears to be a case report related to Crohn's disease, Infliximab, and Anti-TNF. The original article is from Polish archives of internal medicine.

Based on the title and source metadata, this appears to be a clinical study related to Crohn's disease, Inflammatory bowel disease, and Tests and monitoring. The original article is from Gastro hep advances.

EEN is a common treatment in paediatric Crohn's disease. Understanding the burdens and support needs can help families and clinicians plan practical, social, and school-based supports to improve adherence and experience...

Self-esteem, body image, mental health, and sexual satisfaction are linked in women with IBD and can affect quality of life. Addressing these issues in routine care may improve overall wellbeing and adaptation to chronic...

This study suggests transgender and gender non-conforming people with IBD may face longer diagnostic delays, higher psychiatric comorbidity, and possibly more hospitalisations or surgery. That could mean gaps in care or...

The study proposes a machine learning approach to identify SNPs linked to Crohn’s disease risk, which could help researchers prioritize genetic variants for further study and, eventually, contribute to risk prediction or...

Personal stories can show how severe and disruptive Crohn’s symptoms can be, and that diagnosis may take time. The account also reinforces that Crohn’s is chronic and may require ongoing medical treatment plus lifestyle...

A child with Crohn’s disease is helping launch a national Halloween fundraiser that raises money for Children’s Health Ireland services and research; families affected by pediatric IBD may benefit from or want to support...

Cure8 found this source from tipranks.com, but the page could not be read reliably yet. It is tagged for Crohn's disease, Inflammatory bowel disease, and Ontunisertib. Open the original article for the full details.

Positive results and a planned Phase 2b study suggest ontunisertib is progressing in development for fibrostenosing Crohn’s disease — a condition with limited targeted therapies for intestinal fibrosis.

Cure8 found this source from app.dealroom.co, but the page could not be read reliably yet. It is tagged for Crohn's disease, Inflammatory bowel disease, and Ontunisertib. Open the original article for the full details.

People with IBD who have failed multiple advanced therapies are often the most difficult to treat, yet this review shows they are under-represented in clinical trials. That limits direct evidence about how well new...

The study links a common compound in plant foods (oxalate) to intestinal inflammation in IBD, suggesting diet and oxalate metabolism may be modifiable contributors to flares.

Based on the title and source metadata, this appears to be a case report related to Crohn's disease and Symptoms and flares. The original article is from Clinical and experimental dermatology.

The work helps explain why smoking increases Crohn’s risk but seems protective for ulcerative colitis by identifying genetic loci and smoking-dependent gene expression changes that differ between the two diseases. That...

Standardised care pathways may reduce hospital admissions and help health systems manage the burden of IBD without worsening patient-reported disease control.

Patients with refractory IBD or those not fully responding to single targeted therapies may be interested because ACT aims to control multiple inflammatory pathways and could offer improved symptom and endoscopic...

Fibrostenosing (stricturing) Crohn’s disease is a major cause of complications and surgeries. Early-phase clinical results about a therapy targeting fibrotic strictures could matter to people facing strictures or...

If genetics helps explain who develops Crohn’s disease, better ways to pick the handful of important variants could speed discovery of biological mechanisms and future tests.

Based on the title and source metadata, this appears to be a clinical trial phase 3 related to Crohn's disease, Inflammatory bowel disease, and Research and clinical trials. The original article is from msn.com.

Cure8 could only read part of this source from benzinga.com, so this card uses cautious topic tags instead of a full summary. It is tagged for Crohn's disease, Inflammatory bowel disease, and Research and clinical...

This report describes open‑label extension data for ontunisertib, an investigational oral drug being tested specifically for fibrostenosing Crohn’s disease.

This funding supports early-stage research that could identify new biological pathways and targets for treatment, which may eventually lead to more precise therapies or ways to prevent recurrence after surgery. It also...

Bright, round objects on stomach CT scans can be mistaken for retained pills or bleeding. For people with Crohn's disease who commonly receive CT enterography and may have bile reflux or duodenal narrowing, this report...

Cure8 could only read part of this source from tradingview.com, so this card uses cautious topic tags instead of a full summary. It is tagged for Crohn's disease, Inflammatory bowel disease, and Ontunisertib.

Research funding supports early-stage studies that could identify new causes, targets, or tests for Crohn’s disease and ulcerative colitis. Progress in these areas may lead to more personalized treatments or prevention...

Atypical colitis occurring after rituximab is relevant to patients and clinicians because it may mimic Crohn's disease and require different management; recognizing drug‑associated colitis could affect diagnostic workup...

Based on the title and source metadata, this appears to be a patient education related to Crohn's disease, Inflammatory bowel disease, and Research and clinical trials. The original article is from nature.com.