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Diet and lifestyle

Nutrition, food, supplements, exercise, sleep, stress, and lifestyle research for Crohn's disease and IBD.

Page 3 of 24 · 1123 articles

Hybrid Molecular Imaging Using PET/CT and PET/MRI in Inflammatory Bowel Disease: Current Applications, Challenges, and Future Perspectives.
Medical science monitor : international medical journal of experimental and clinical research

Hybrid Molecular Imaging Using PET/CT and PET/MRI in Inflammatory Bowel Disease: Current Applications, Challenges, and Future Perspectives.

Noninvasive imaging that better separates inflammation from fibrosis and detects penetrating complications could change monitoring and treatment decisions in IBD and reduce radiation exposure for patients needing...

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Sargassum soluble dietary fiber alleviates oxidative stress and gut microbiota dysbiosis to prevent inflammatory bowel disease in C57BL/6 mice.
Journal of the science of food and agriculture

Sargassum soluble dietary fiber alleviates oxidative stress and gut microbiota dysbiosis to prevent inflammatory bowel disease in C57BL/6 mice.

The study suggests a fermented seaweed-derived fiber reduced inflammation and oxidative stress in cells and a mouse colitis model and modified gut microbiota and short-chain fatty acids, which could guide future dietary...

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Chronic Ultrasound (‘Emotional’) Stress in Mice Exacerbates Colitis Through GSK3β-Mediated Neuroimmune Dysregulation and Is Ameliorated by Probiotic Intervention
International Journal of Molecular Sciences

Chronic Ultrasound (‘Emotional’) Stress in Mice Exacerbates Colitis Through GSK3β-Mediated Neuroimmune Dysregulation and Is Ameliorated by Probiotic Intervention

The study suggests psychological (emotional) stress can worsen colitis-like inflammation via GSK3β-mediated neuroimmune changes, and that a probiotic (VSL#3) reduced many adverse effects in mice — relevant to...

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Early-life animal exposure was not associated with risk of inflammatory bowel disease: a nationwide birth cohort study.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Early-life animal exposure was not associated with risk of inflammatory bowel disease: a nationwide birth cohort study.

This large, long-term study suggests that having pets or farm animals during pregnancy or early childhood probably does not meaningfully change a child’s later risk of developing IBD, which may reassure families...

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L-Proline Alleviates Dextran Sulfate Sodium-Induced Colitis by Remodeling Gut Microbiota and Inhibiting the NF-κB/STAT3 Signaling Pathway
MDPI AG

L-Proline Alleviates Dextran Sulfate Sodium-Induced Colitis by Remodeling Gut Microbiota and Inhibiting the NF-κB/STAT3 Signaling Pathway

The study suggests L‑proline can reduce colitis in a mouse model and reshapes the gut microbiome, raising the possibility that amino-acid–based dietary strategies might influence intestinal inflammation through...

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Nanoformulated Curcumin Ameliorates Ulcerative Colitis via Gut Microbiota Modulation and Barrier Function Restoration
The American Journal of Chinese Medicine

Nanoformulated Curcumin Ameliorates Ulcerative Colitis via Gut Microbiota Modulation and Barrier Function Restoration

People with ulcerative colitis may be interested because the study explores a way to boost curcumin’s activity and suggests gut microbiota changes could underlie protection against colitis.

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Inflammatory bowel disease and breast cancer: epidemiological evidence, shared biology, and clinical management.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]

Inflammatory bowel disease and breast cancer: epidemiological evidence, shared biology, and clinical management.

This review addresses whether people with IBD face higher breast cancer risk and how treatments for one disease might affect the other—questions many patients and clinicians raise when cancer and IBD overlap.

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Propolis Flavonoids: Current Evidence in Animal Models and Future Promise for the Treatment of Ulcerative Colitis
International Journal of Molecular Sciences

Propolis Flavonoids: Current Evidence in Animal Models and Future Promise for the Treatment of Ulcerative Colitis

People with ulcerative colitis may be interested because the review identifies flavonoids in propolis as compounds that reduce inflammation and strengthen the gut barrier in animal models, and it highlights strategies to...

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β-Glucan-based oral nano/micro delivery systems: harnessing dual immunomodulatory and microbiota-modulating properties for targeted therapy of cancer and inflammatory bowel disease.
Nanoscale

β-Glucan-based oral nano/micro delivery systems: harnessing dual immunomodulatory and microbiota-modulating properties for targeted therapy of cancer and inflammatory bowel disease.

Researchers are exploring new oral delivery carriers that could deliver drugs directly to inflamed intestinal sites while also modulating immune responses and the gut microbiome. If translated, these approaches might...

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A Mesalazine–Aloperine Co-Amorphous System for Simultaneous Dissolution Enhancement, Permeability Improvement, and Synergistic Anti-Ulcerative Colitis Activity: A Combined Pharmaceutics and Network Pharmacology Study
Pharmaceutics

A Mesalazine–Aloperine Co-Amorphous System for Simultaneous Dissolution Enhancement, Permeability Improvement, and Synergistic Anti-Ulcerative Colitis Activity: A Combined Pharmaceutics and Network Pharmacology Study

Improving mesalazine delivery could increase drug reaching the colon and potentially improve treatment for ulcerative colitis. A formulation that both enhances dissolution/permeability and offers mechanistic synergy...

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Gut microbiota, microbial metabolites, and mucosal barrier dysfunction in benign anorectal disorders and ulcerative colitis: shared mechanisms, clinical links, and precision interventions
Frontiers in Medicine

Gut microbiota, microbial metabolites, and mucosal barrier dysfunction in benign anorectal disorders and ulcerative colitis: shared mechanisms, clinical links, and precision interventions

The review links microbiome, metabolites, barrier function, and immune responses across anorectal disorders and ulcerative colitis — areas that directly affect symptoms, healing, and response to therapy.

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Dietary Polyphenols as Adjunctive Therapy for Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Nutrients

Dietary Polyphenols as Adjunctive Therapy for Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

People with IBD often ask about dietary supplements. This systematic review suggests some randomized-trial evidence that polyphenol supplements—especially curcumin—may help induce clinical improvement in ulcerative...

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Type 6 secretion systems of adherent-invasive Escherichia coli isolated from Crohn's disease patients shape intestinal microbiota.
Europe PMC

Type 6 secretion systems of adherent-invasive Escherichia coli isolated from Crohn's disease patients shape intestinal microbiota.

The study identifies a bacterial mechanism (T6SS) that may help AIEC strains compete with normal gut microbes and colonize the intestinal mucosa — a process relevant to Crohn’s disease biology and future...

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Four dietary flavonoids differentially modulate the gut microbiota–barrier interaction against colitis-driven cognitive deficits
npj Science of Food

Four dietary flavonoids differentially modulate the gut microbiota–barrier interaction against colitis-driven cognitive deficits

Preclinical evidence suggests certain dietary flavonoids may protect the gut barrier, reshape the microbiome, and reduce neuroinflammation, which could be relevant to colitis-linked cognitive problems. This points to...

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Tauroursodeoxycholic acid ameliorates DSS-induced ulcerative colitis via regulating TLR4/NLRP3/pyroptosis axis and Keap1/Nrf2 pathway and restoring gut barrier function.
European journal of pharmacology

Tauroursodeoxycholic acid ameliorates DSS-induced ulcerative colitis via regulating TLR4/NLRP3/pyroptosis axis and Keap1/Nrf2 pathway and restoring gut barrier function.

The study identifies a bile acid, TUDCA, that reduced colitis severity and improved gut-barrier and antioxidant pathways in mice, pointing to a potential new therapeutic approach for intestinal inflammation. This is...

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Changing Prescription Patterns in Pharmacologically Treated Patients with Newly Diagnosed Inflammatory Bowel Disease in German Gastroenterology Practices: A Real-World Study, 2015–2024
Pharmaceuticals

Changing Prescription Patterns in Pharmacologically Treated Patients with Newly Diagnosed Inflammatory Bowel Disease in German Gastroenterology Practices: A Real-World Study, 2015–2024

The study documents shifting real-world prescribing for newly diagnosed IBD in Germany, with more biologic use and less mesalazine/thiopurine in recent years — changes that could affect treatment expectations and access.

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Microbiota–host crosstalk in ulcerative colitis: mechanistic evidence and translational prospects for traditional Chinese medicine
Frontiers in Pharmacology

Microbiota–host crosstalk in ulcerative colitis: mechanistic evidence and translational prospects for traditional Chinese medicine

People with ulcerative colitis may be interested because the review explains how the gut microbiome and its metabolites could influence disease and evaluates whether traditional Chinese medicines might modify those...

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Protocol: Early Intestinal Ultrasonography for Prediction of Response to Corticosteroids or Biologics in Outpatients With Moderate to Severe Ulcerative Colitis
JCC Plus

Protocol: Early Intestinal Ultrasonography for Prediction of Response to Corticosteroids or Biologics in Outpatients With Moderate to Severe Ulcerative Colitis

If validated, early bedside ultrasound changes could let clinicians identify within days whether steroids or biologics are working, enabling faster treatment adjustments and potentially avoiding prolonged ineffective...

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The burden of inflammatory bowel disease in Asia (1990-2023) and projections to 2050: A comprehensive analysis of the 2023 global burden of disease study.
PloS one

The burden of inflammatory bowel disease in Asia (1990-2023) and projections to 2050: A comprehensive analysis of the 2023 global burden of disease study.

Rising IBD incidence and prevalence in Asia mean more people will need long-term care, specialist services, and health-system planning. Understanding regional trends helps patients and policymakers anticipate resource...

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Chinese herbal medicine for ulcerative colitis: product-level clinical evidence, mechanistic appraisal, and a roadmap to precision translation
Frontiers in Pharmacology

Chinese herbal medicine for ulcerative colitis: product-level clinical evidence, mechanistic appraisal, and a roadmap to precision translation

People with UC often try complementary therapies; this review shows that benefits and risks vary by specific CHM product and that current evidence is mixed and product-dependent.

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Titanium dioxide exposure during gestation is critical to worsen DSS-induced colitis
Springer Science and Business Media LLC

Titanium dioxide exposure during gestation is critical to worsen DSS-induced colitis

If findings translate beyond mice, exposure to titanium dioxide during pregnancy could influence offspring gut barrier, microbiota, and susceptibility to inflammatory colitis — a potential public-health concern for...

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