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Diet and lifestyle

Nutrition, food, supplements, exercise, sleep, stress, and lifestyle research for Crohn's disease and IBD.

Page 3 of 13 · 577 articles

Spatial Modulation of Immune Cell Distribution and Pro- and Anti-Inflammatory Cytokines by Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) in a Preclinical Model of Ulcerative Colitis: A Descriptive Study.
Journal of inflammation research

Spatial Modulation of Immune Cell Distribution and Pro- and Anti-Inflammatory Cytokines by Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) in a Preclinical Model of Ulcerative Colitis: A Descriptive Study.

This study suggests noninvasive vagus nerve stimulation (taVNS) can reduce colonic inflammation and change immune signals regionally in a mouse model of ulcerative colitis—supporting a possible neuroimmune approach worth...

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Testing-Yield Mismatch in Inpatient Micronutrient Assessment in Inflammatory Bowel Disease: A Real-World Implementation-Gap Analysis
Nutrients

Testing-Yield Mismatch in Inpatient Micronutrient Assessment in Inflammatory Bowel Disease: A Real-World Implementation-Gap Analysis

Micronutrient deficiencies are common in IBD and can worsen anemia, healing, and neurologic function. This study shows inpatient testing focuses on B12 while missing other commonly deficient nutrients (B1, B6, zinc),...

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Azoreductase-Responsive NIR Fluorescent Self-Assembled Probe for Hypoxia Imaging of Tumors, Hindlimb Ischemia, and Ulcerative Colitis
Analytical Chemistry

Azoreductase-Responsive NIR Fluorescent Self-Assembled Probe for Hypoxia Imaging of Tumors, Hindlimb Ischemia, and Ulcerative Colitis

The probe targets azoreductase-driven hypoxia, a mechanism linked to ulcerative colitis and other hypoxia-associated diseases; a reliable real-time imaging method could help research and eventually guide treatments.

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Author Correction: Engineered living glues secrete therapeutic proteins for treatment of inflammatory bowel disease
Nature Biotechnology

Author Correction: Engineered living glues secrete therapeutic proteins for treatment of inflammatory bowel disease

This correction updates duplicated data points and clarifies methods in a preclinical synthetic-biology study about engineered materials that secrete therapeutic proteins for IBD, which affects interpretation and...

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Malnutrition Risk, Nutrition Insecurity, Barriers, and Facilitators to Dietary Management Among Adults with Inflammatory Bowel Disease in the US Rocky Mountain Region: A Cross-Sectional Mixed-Methods Study
Dietetics

Malnutrition Risk, Nutrition Insecurity, Barriers, and Facilitators to Dietary Management Among Adults with Inflammatory Bowel Disease in the US Rocky Mountain Region: A Cross-Sectional Mixed-Methods Study

Malnutrition risk and nutrition insecurity can affect symptom management and overall health for people with IBD. Understanding barriers and supports helps target practical services (dietitians, social resources, digital...

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Orally administrable photo-crosslinked coumaroyl-modified gelatin-CNC nanofibers for ulcerative colitis environment-triggered release of 5-aminosalicylic acid
Journal of Nanobiotechnology

Orally administrable photo-crosslinked coumaroyl-modified gelatin-CNC nanofibers for ulcerative colitis environment-triggered release of 5-aminosalicylic acid

Targeted release of mesalamine to the colon could increase local drug levels and reduce upper-GI exposure and systemic side effects. New delivery platforms may improve effectiveness for ulcerative colitis without...

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Lactobacillus plantarum Attenuates Intestinal Inflammation and Prolongs Remission in Experimental Models of Crohn’s Disease
Probiotics and Antimicrobial Proteins

Lactobacillus plantarum Attenuates Intestinal Inflammation and Prolongs Remission in Experimental Models of Crohn’s Disease

The study suggests a probiotic strain (Lactobacillus plantarum) reduced inflammation and prolonged remission in multiple mouse models of Crohn’s-like disease, indicating microbiome-based approaches might be promising to...

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Guchang capsule alleviates inflammatory bowel disease by downregulating lncRNA THRIL and inhibiting the p38 MAPK/NF-κB signaling pathway.
Molecular immunology

Guchang capsule alleviates inflammatory bowel disease by downregulating lncRNA THRIL and inhibiting the p38 MAPK/NF-κB signaling pathway.

The study identifies a possible molecular mechanism (THRIL downregulation and inhibition of p38 MAPK/NF-κB) by which a traditional Chinese medicine preparation reduced inflammation in mouse and cell models of colitis,...

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Cross-Disease Microbiome Signatures Associated with Autoimmune Disorders: A Comparative Meta-Analysis of Public Sequencing Datasets
Europe PMC

Cross-Disease Microbiome Signatures Associated with Autoimmune Disorders: A Comparative Meta-Analysis of Public Sequencing Datasets

Shared gut microbiome shifts across autoimmune diseases could suggest common microbial factors relevant to immune regulation and might eventually inform diagnostics or therapies relevant to people with IBD.

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Chinese Medical Journal review highlights the role of artificial intelligence in inflammatory ...
eurekalert.org

Chinese Medical Journal review highlights the role of artificial intelligence in inflammatory ...

AI could help make IBD assessments (endoscopy, histology, imaging, biomarkers) more objective and faster, which may improve monitoring, treatment selection, and early detection of complications for people with Crohn’s...

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Periodontitis, Edentulism, and Risk of Inflammatory Bowel Disease (IBD): A Systematic Review With Meta-Analysis.
Journal of periodontal research

Periodontitis, Edentulism, and Risk of Inflammatory Bowel Disease (IBD): A Systematic Review With Meta-Analysis.

If you have IBD, the mouth and gums may be part of shared inflammatory pathways with your gut. Periodontitis is associated with higher odds of having IBD in cross-sectional studies and has a modest link to later...

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The Efficacy of Lactobacillous Probiotic and Trace Elements in the Management of Ulcerative Colitis Patients the Patient Will be Recruited From Outpatient Clinic of IBD and Gastroenterology of the National Hepatology and Tropical Medicine Research Institute (NHTMRI), Cairo, Egypt.
ClinicalTrials.gov

The Efficacy of Lactobacillous Probiotic and Trace Elements in the Management of Ulcerative Colitis Patients the Patient Will be Recruited From Outpatient Clinic of IBD and Gastroenterology of the National Hepatology and Tropical Medicine Research Institute (NHTMRI), Cairo, Egypt.

The trial tests two low-cost adjuncts — a Lactobacillus probiotic and a multi–trace-element supplement — added to biologic-based standard care to see if they help maintain remission in ulcerative colitis. If effective,...

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Global gut microbiome atlas identifies epidemiologic-stage-specific signatures in inflammatory bowel disease.
Cell reports. Medicine

Global gut microbiome atlas identifies epidemiologic-stage-specific signatures in inflammatory bowel disease.

This study links population-level IBD epidemiology to gut microbiome changes and proposes a microbial risk score that might help detect or surveil IBD patterns. That could inform future biomarker development or...

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The Aloe vera polysaccharides in inflammatory bowel disease: An ethnopharmacological review on the mechanisms of intestinal barrier repair and immunomodulation.
Journal of ethnopharmacology

The Aloe vera polysaccharides in inflammatory bowel disease: An ethnopharmacological review on the mechanisms of intestinal barrier repair and immunomodulation.

This review suggests Aloe vera polysaccharides could support gut barrier repair, microbiome balance, and immune regulation—mechanisms relevant to IBD inflammation and healing. However, evidence is mainly preclinical and...

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Nanomaterial-based modulation of inflammatory and cytokine networks for precision therapy in inflammatory bowel disease.
International journal of pharmaceutics

Nanomaterial-based modulation of inflammatory and cytokine networks for precision therapy in inflammatory bowel disease.

Nanotechnology approaches aim to improve how cytokine-targeting therapies are delivered in IBD, which could reduce systemic exposure and immunogenicity and increase local effectiveness.

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Transfer of FRozen Encapsulated Multidonor Stool Filtrate for Active Ulcerative COlitis
ClinicalTrials.gov

Transfer of FRozen Encapsulated Multidonor Stool Filtrate for Active Ulcerative COlitis

Faecal microbiota transfer is being tested in a large Phase 3 trial as a possible new treatment approach for active ulcerative colitis, and this study also looks at safety and how the therapy changes the gut microbiome...

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Sodium Butyrate Therapy in Ulcerative Colitis: A Systematic Review of Preclinical and Clinical Evidence
Medical Sciences

Sodium Butyrate Therapy in Ulcerative Colitis: A Systematic Review of Preclinical and Clinical Evidence

This review pools available human and animal studies on sodium butyrate for ulcerative colitis and highlights promising signals—especially for oral microencapsulated formulations—while noting that clinical evidence is...

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Probiotic extracellular vesicles loaded with multifunctional nanozymes for inflammatory bowel disease treatment
Springer Science and Business Media LLC

Probiotic extracellular vesicles loaded with multifunctional nanozymes for inflammatory bowel disease treatment

The study explores a novel, combined nanozyme + microbiome-derived vesicle approach aimed at reducing oxidative stress and modulating inflammation in IBD — mechanisms that are relevant to disease pathways and future...

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Integrating virtual docking and neural network modeling to predict the anti-inflammatory potential of dietary polyphenols in ulcerative colitis.
Food & function

Integrating virtual docking and neural network modeling to predict the anti-inflammatory potential of dietary polyphenols in ulcerative colitis.

People with UC often seek dietary strategies to help manage inflammation; this study uses AI and docking to prioritize polyphenols and foods for future testing, which could guide research and eventually inform dietary...

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From Multi-Omics to Molecular Causality: A Five-Tier Evidence Framework for the Single-Bacterium–Metabolite Axis in IBD
Microorganisms

From Multi-Omics to Molecular Causality: A Five-Tier Evidence Framework for the Single-Bacterium–Metabolite Axis in IBD

This review organizes and grades causal evidence linking individual gut bacteria, their metabolites, and host pathways in IBD—helping researchers and clinicians see which microbe–metabolite mechanisms are best supported...

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Association between long-term ambient air pollution and incident inflammatory bowel disease across levels of adherence to a plant-based diet: a prospective cohort study in the UK Biobank
Frontiers in Nutrition

Association between long-term ambient air pollution and incident inflammatory bowel disease across levels of adherence to a plant-based diet: a prospective cohort study in the UK Biobank

If true, the study suggests that long-term air pollution exposure may raise the risk of developing IBD and that greater adherence to a plant-based diet could be linked with a lower pollution-related risk. That may be...

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Engineering of Artificial Antioxidase Enables Boosted Catalytic Activity in Inflammatory Bowel Disease Alleviation.
Angewandte Chemie (International ed. in English)

Engineering of Artificial Antioxidase Enables Boosted Catalytic Activity in Inflammatory Bowel Disease Alleviation.

Researchers are exploring non-drug enzyme-like catalysts to reduce oxidative stress in IBD—this study reports a new artificial antioxidase that helped reduce inflammation in cell and animal models, which could point to...

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Engineered perturbations to define B cell entry, competition, and function in intestinal immunity and inflammation
NIH RePORTER

Engineered perturbations to define B cell entry, competition, and function in intestinal immunity and inflammation

Researchers are exploring a way to deliver biologic drugs directly in the gut using engineered B cells that become long-lived plasma cells. If successful, this could allow sustained, localized anti-inflammatory protein...

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Confirming the association of ulcerative colitis with interstitial lung disease: a retrospective analysis of comorbid disease, demographics, and healthcare utilization.
Crohn's & colitis 360

Confirming the association of ulcerative colitis with interstitial lung disease: a retrospective analysis of comorbid disease, demographics, and healthcare utilization.

ILD is a potentially serious extraintestinal complication that appears more often with ulcerative colitis than with Crohn’s disease in this cohort study. Patients with both IBD and ILD had higher healthcare use and...

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Cod Skin Collagen Peptides Alleviate Ulcerative Colitis by Regulating Gut Microbiota to Inhibit NLRP3 Inflammasome Activation.
Food science & nutrition

Cod Skin Collagen Peptides Alleviate Ulcerative Colitis by Regulating Gut Microbiota to Inhibit NLRP3 Inflammasome Activation.

This preclinical study links cod skin–derived collagen peptides to reduced colitis severity in mice through changes in the gut microbiota and suppression of the NLRP3 inflammasome — pathways that could be relevant to...

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AnEnergy-Sustainable and Oxidative-Tolerant Nanofactoryof Therapeutic Proteins for Long-Acting Therapy of Inflammatory BowelDisease
ACS Nano

AnEnergy-Sustainable and Oxidative-Tolerant Nanofactoryof Therapeutic Proteins for Long-Acting Therapy of Inflammatory BowelDisease

Researchers are exploring ways to produce anti-inflammatory proteins directly at inflamed gut sites; this study describes a nanomaterial system intended to protect plasmid drugs and supply oxygen to sustain local protein...

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Multi-Omics-Driven Network Pharmacology and Experimental Validation Reveal the Molecular Mechanism of Bupi Yichang Pill in Treating Ulcerative Colitis Through Regulation of the PI3K/Akt/IKK/NF-κB Pathway.
Journal of ethnopharmacology

Multi-Omics-Driven Network Pharmacology and Experimental Validation Reveal the Molecular Mechanism of Bupi Yichang Pill in Treating Ulcerative Colitis Through Regulation of the PI3K/Akt/IKK/NF-κB Pathway.

This study explores a multi-component traditional medicine that the authors report can reduce experimental colitis and modulate inflammatory signaling and the gut microbiome — findings that could guide future preclinical...

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Two birds with one stone: Charge flip assisted colon-targeting hybrid nanoplatform for both drug delivery and proinflammatory factor scavenging.
Colloids and surfaces. B, Biointerfaces

Two birds with one stone: Charge flip assisted colon-targeting hybrid nanoplatform for both drug delivery and proinflammatory factor scavenging.

This study reports an early-stage nanoplatform that combines targeted colon delivery of an aminosalicylate prodrug with scavenging of proinflammatory cfDNA, a dual strategy that reduced colitis severity in mice and could...

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Pseudo-tumoral left-colonic tuberculosis causing acute large-bowel obstruction: a case report and review of the literature
International Journal of Surgery Case Reports

Pseudo-tumoral left-colonic tuberculosis causing acute large-bowel obstruction: a case report and review of the literature

This is relevant because a treatable infection (intestinal tuberculosis) can present like colorectal cancer or IBD and lead to emergency surgery. Recognizing it earlier could change management and avoid unnecessary...

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Life-course body size trajectories and polygenic risk for incident inflammatory bowel disease
Scientific Reports

Life-course body size trajectories and polygenic risk for incident inflammatory bowel disease

This study examines whether patterns of body size from birth through adulthood add information about IBD risk beyond adult BMI and genetic susceptibility. Results suggest life-course size trajectories may be more related...

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