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Pediatrics and family

Children, teens, growth, school, parents, caregivers, and family-centered IBD updates.

Page 2 of 8 · 376 articles

Dose Ranging Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Rectal Foam in Pediatric Patients Aged 5 to 17 Years With Active, Mild to Moderate Distal Ulcerative Colitis
ClinicalTrials.gov

Dose Ranging Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Rectal Foam in Pediatric Patients Aged 5 to 17 Years With Active, Mild to Moderate Distal Ulcerative Colitis

A pediatric trial of budesonide rectal foam could provide evidence about a locally acting steroid option for children with distal ulcerative colitis. Trial results may affect treatment choices for pediatric distal...

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Post-Operative Ketorolac in Children After Crohn's Ileocecectomy.
Pediatric surgery international

Post-Operative Ketorolac in Children After Crohn's Ileocecectomy.

Postoperative pain control choices after ileocecectomy could affect Crohn's flare risk and opioid exposure. A pediatric center-level analysis found no association between ketorolac and flares and suggested reduced opioid...

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Integrated genetic and functional analyses reveal the pathogenic effects of a novel STXBP3 variant in very-early-onset inflammatory bowel disease with immunodeficiency
Frontiers in Immunology

Integrated genetic and functional analyses reveal the pathogenic effects of a novel STXBP3 variant in very-early-onset inflammatory bowel disease with immunodeficiency

The study identifies and functionally validates a new STXBP3 variant that likely causes VEOIBD with immunodeficiency, which can help explain disease in affected infants and inform genetic counseling and further research.

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Bone health and vitamin D status in Korean children with inflammatory bowel disease: a retrospective cohort study
Annals of Pediatric Endocrinology & Metabolism

Bone health and vitamin D status in Korean children with inflammatory bowel disease: a retrospective cohort study

Cure8 could only read part of this source from Annals of Pediatric Endocrinology & Metabolism, so this card uses cautious topic tags instead of a full summary. It is tagged for Inflammatory bowel disease and Pediatrics...

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Treatment burden, adaptation, and support needs during exclusive enteral nutrition in children with Crohn's disease: a qualitative meta-synthesis.
Frontiers in nutrition

Treatment burden, adaptation, and support needs during exclusive enteral nutrition in children with Crohn's disease: a qualitative meta-synthesis.

EEN is a common treatment in paediatric Crohn's disease. Understanding the burdens and support needs can help families and clinicians plan practical, social, and school-based supports to improve adherence and experience...

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Clinical and Psychosocial Burden of Inflammatory Bowel Disease Among Transgender Individuals: A National BioResource Cohort Study

This study suggests transgender and gender non-conforming people with IBD may face longer diagnostic delays, higher psychiatric comorbidity, and possibly more hospitalisations or surgery. That could mean gaps in care or...

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Best-practice recommendations for the transition care pathway for children and young people with moderate to severe ulcerative colitis: a modified Delphi panel with UK health care professionals
Frontline Gastroenterology

Best-practice recommendations for the transition care pathway for children and young people with moderate to severe ulcerative colitis: a modified Delphi panel with UK health care professionals

Transition from paediatric to adult services is a high-risk period for gaps in care. Consensus recommendations aim to standardise pathways, support young people’s needs, and reduce barriers to effective treatment.

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Experiences and Factors Influencing the Transition to Adult Care in Adolescents With Inflammatory Bowel Disease: A Mixed-Methods Systematic Review.
Journal of clinical nursing

Experiences and Factors Influencing the Transition to Adult Care in Adolescents With Inflammatory Bowel Disease: A Mixed-Methods Systematic Review.

Transition to adult care is a high-risk time when adolescents with IBD can experience care gaps and worsened disease control. Understanding which fixed and modifiable factors affect transition can help patients,...

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Between-visit care represents a substantial and underrecognized component of health care utilization in pediatric inflammatory bowel disease
PubMed Central

Between-visit care represents a substantial and underrecognized component of health care utilization in pediatric inflammatory bowel disease

If you or your child has pediatric-onset IBD, much of the care that supports disease management happens between scheduled visits. Recognizing this workload matters for access, clinician time, and policies that affect...

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Upadacitinib Maintenance Therapy in Pediatric Ulcerative Colitis: 52-Week Multicenter Study From the Porto Group of the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition
Clinical Gastroenterology and Hepatology

Upadacitinib Maintenance Therapy in Pediatric Ulcerative Colitis: 52-Week Multicenter Study From the Porto Group of the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition

Based on the title and source metadata, this appears to be a clinical trial phase 3 related to Ulcerative colitis, Inflammatory bowel disease, and Upadacitinib. The original article is from Clinical Gastroenterology and...

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Contraception Among Women with Selected Autoimmune Diseases in the United States, 2019: A Claims Analysis.
PubMed

Contraception Among Women with Selected Autoimmune Diseases in the United States, 2019: A Claims Analysis.

Many reproductive-aged women with IBD and other autoimmune conditions may not have documented claims for prescription or permanent contraception, including women taking medications with potential fetal risks. That gap...

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Peripartum mental illness in serial pregnancies in mothers with multiple sclerosis and other chronic diseases.
Multiple sclerosis (Houndmills, Basingstoke, England)

Peripartum mental illness in serial pregnancies in mothers with multiple sclerosis and other chronic diseases.

Mothers with chronic diseases such as MS and IBD appear to have higher rates of peripartum mental illness requiring care across serial pregnancies, so awareness and monitoring during and between pregnancies may be...

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Health Related Quality of Life in Patients with Inflammatory Bowel Disease in Department of Gastroenterology of Dhaka Medical College Hospital: An Observational Study.
Mymensingh medical journal : MMJ

Health Related Quality of Life in Patients with Inflammatory Bowel Disease in Department of Gastroenterology of Dhaka Medical College Hospital: An Observational Study.

Quality of life is often substantially affected in IBD; this study identifies active disease, greater severity, prior surgery, and stricturing Crohn's disease as factors linked to lower HRQoL, highlighting areas...

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Intestinal ultrasound versus magnetic resonance enterography for detecting small bowel Crohn's disease in children.
Journal of pediatric gastroenterology and nutrition

Intestinal ultrasound versus magnetic resonance enterography for detecting small bowel Crohn's disease in children.

Children with Crohn's and their clinicians often need noninvasive, accessible ways to monitor small-bowel disease. If validated elsewhere, IUS with the reported BWT thresholds could reduce reliance on MRE, which is...

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Burden of Mental Disorders and Related Factors in Pediatric Patients with Ulcerative Colitis in Korea
Journal of Pharmacoepidemiology and Risk Management

Burden of Mental Disorders and Related Factors in Pediatric Patients with Ulcerative Colitis in Korea

This paper suggests children and teens with ulcerative colitis have higher rates of diagnosed mental disorders and antidepressant use compared with peers, indicating mental-health needs are an important part of pediatric...

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Subcutaneous infliximab for maintenance therapy in children and adolescents with inflammatory bowel disease: a systematic review and meta-analysis.
European journal of pediatrics

Subcutaneous infliximab for maintenance therapy in children and adolescents with inflammatory bowel disease: a systematic review and meta-analysis.

Children with IBD and their caregivers may be interested in subcutaneous infliximab as an alternative to regular IV infusions because this review suggests it can maintain drug levels and remission after switching, with...

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Influencing factors of health-related productivity loss among patients with inflammatory bowel disease in paid employment based on the theory of social ecosystem: a mixed-methods study.
Minerva gastroenterology

Influencing factors of health-related productivity loss among patients with inflammatory bowel disease in paid employment based on the theory of social ecosystem: a mixed-methods study.

Work-related productivity loss was common in this study and linked to both clinical (disease activity, strictures, fatigue) and psychosocial factors (anxiety, depression, self-efficacy, social support).

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Decoding Personalized Nutritional, Microbiome and Host Patterns Impacting Clinical and Prognostic Features in Crohn's Disease
ClinicalTrials.gov

Decoding Personalized Nutritional, Microbiome and Host Patterns Impacting Clinical and Prognostic Features in Crohn's Disease

Understanding how individual diet and microbiome patterns relate to disease activity could help create personalized dietary approaches for children with Crohn's disease and improve monitoring using home fecal...

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B.C. couple gives $10 million gift for digestive health centre at St. Paul's Hospital - Vancouver Sun
vancouversun.com

B.C. couple gives $10 million gift for digestive health centre at St. Paul's Hospital - Vancouver Sun

A dedicated Digestive Health Centre could make it easier for people with IBD (including children and teens) to access coordinated care—fewer separate visits and more centralized specialist services in one location.

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A Practical Approach to Abnormal Liver Enzymes in Pediatric IBD in the Biologic and Targeted Therapy Era.
Clinics and research in hepatology and gastroenterology

A Practical Approach to Abnormal Liver Enzymes in Pediatric IBD in the Biologic and Targeted Therapy Era.

Abnormal liver tests are common in children with IBD and can come from many causes, including the disease itself or the medicines used to treat it. A practical approach helps avoid stopping effective IBD therapy...

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Improving Endoscopic Scoring Accuracy in Pediatric Inflammatory Bowel Disease: Impact of a Focused Training Intervention
Endoscopy International Open

Improving Endoscopic Scoring Accuracy in Pediatric Inflammatory Bowel Disease: Impact of a Focused Training Intervention

Consistent, accurate endoscopic scoring matters for treatment decisions and trial outcomes in pediatric IBD. If focused training meaningfully improves scoring—especially for SES‑CD—it could reduce variability in clinical...

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Anti-TNF-refractory inflammatory bowel disease associated with a novel XIAP frameshift variant successfully treated with ustekinumab.
Clinical journal of gastroenterology

Anti-TNF-refractory inflammatory bowel disease associated with a novel XIAP frameshift variant successfully treated with ustekinumab.

Identifying a genetic cause (XIAP frameshift variant) helped explain why anti‑TNF drugs failed and why blocking IL‑12/23 with ustekinumab led to improvement; that connection could influence treatment choices for similar...

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Upadacitinib treatment in pediatric Crohn's disease: 52-week outcomes of an international multicenter retrospective cohort study from the pediatric IBD Porto Group of ESPGHAN.
Journal of Crohn's & colitis

Upadacitinib treatment in pediatric Crohn's disease: 52-week outcomes of an international multicenter retrospective cohort study from the pediatric IBD Porto Group of ESPGHAN.

This study gives real-world 52‑week data on upadacitinib maintenance in children with refractory Crohn's disease, showing meaningful remission rates but also notable adverse events. That balance is important for families...

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Psychological Pathways From Disease Activity to Quality of Life in Ulcerative Colitis and Crohn's Disease: A Cross‐Sectional Serial Mediation Study
Journal of Clinical Nursing

Psychological Pathways From Disease Activity to Quality of Life in Ulcerative Colitis and Crohn's Disease: A Cross‐Sectional Serial Mediation Study

If disease activity hurts quality of life partly through low self-efficacy and (for UC) psychological distress, then boosting self-management confidence and identifying anxiety/depression could help improve...

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Clinical phenotypes of very early onset inflammatory bowel disease in Australian children: A single-centre retrospective study.
Journal of pediatric gastroenterology and nutrition

Clinical phenotypes of very early onset inflammatory bowel disease in Australian children: A single-centre retrospective study.

VEO-IBD often presents with severe, extensive disease and can include monogenic causes and early hepatobiliary complications; knowing common presentations and early management patterns helps families and clinicians plan...

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Disability in pediatric inflammatory bowel diseases: A systematic review and a single center experience
Journal of Pediatric Gastroenterology and Nutrition

Disability in pediatric inflammatory bowel diseases: A systematic review and a single center experience

Disability and functional limitations (school, sports, travel, diet) are common early after pediatric IBD diagnosis and can persist for some children even after clinical remission. Recognizing and measuring disability...

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Machine Learning Predicts First Elective Bowel Resection in Newly Diagnosed Pediatric Crohn Disease Patients.
Journal of pediatric surgery

Machine Learning Predicts First Elective Bowel Resection in Newly Diagnosed Pediatric Crohn Disease Patients.

Predicting which children with Crohn disease will need surgery — and roughly when — could help families and clinicians plan treatments, monitoring, and discussions about elective bowel resection earlier in the disease...

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Appropriate screening strategy and timely referral in suspected pediatric inflammatory bowel disease: Impact on diagnostic delay and severity at presentation.
Journal of pediatric gastroenterology and nutrition

Appropriate screening strategy and timely referral in suspected pediatric inflammatory bowel disease: Impact on diagnostic delay and severity at presentation.

Delays and incomplete pre-referral screening are common in pediatric IBD and can affect how sick children are when they first see specialists. Better, standardized use of fecal calprotectin and abdominal ultrasound...

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Generational differences in illness perception among adults with inflammatory bowel disease: a multicenter cross-sectional study.
European journal of gastroenterology & hepatology

Generational differences in illness perception among adults with inflammatory bowel disease: a multicenter cross-sectional study.

How patients think about their IBD affects coping, treatment adherence, and quality of life. If different generations perceive illness threat and control differently, clinicians and care teams may need to tailor...

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Oral manifestations of Crohn's disease: a clinical image highlighting the importance of interdisciplinary gastroenterological and dental care.
Polish archives of internal medicine

Oral manifestations of Crohn's disease: a clinical image highlighting the importance of interdisciplinary gastroenterological and dental care.

Based on the title and source metadata, this appears to be a patient education related to Crohn's disease, Inflammatory bowel disease, and Symptoms and flares. The original article is from Polish archives of internal...

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