Pediatrics and family

PSC commonly co-occurs with IBD in children; understanding clinical phenotypes and reliable monitoring tools helps families and clinicians track disease and plan follow-up.

Older adults with IBD face tradeoffs between effectiveness and safety of advanced therapies; this study aims to identify immune‑aging and frailty markers that might predict who is more likely to benefit without serious...

Children with IBD are at higher risk for C. difficile and practices for diagnosing and treating CDI in pediatric IBD vary widely. Standardized, pediatric-specific guidance could reduce uncertainty and improve care.

This study identifies modifiable lifestyle factors (meal regularity and spicy/sour food intake) linked to quality of life in people with IBD, which could inform practical counseling for patients.

Based on the title and source metadata, this appears to be a case report related to Crohn's disease and Pediatrics and family. The original article is from Frontiers in pediatrics.

MRE is a key radiation-free imaging tool for children with Crohn’s disease; this review summarizes its clinical utility and how it fits with other pediatric-focused diagnostic approaches in Japan.

Erythema nodosum can signal an underlying infection or systemic disease (including IBD) in children; recognizing common triggers helps guide evaluation and treatment.

A decreasing need for IBD-related surgery after pediatric diagnosis could mean fewer major operations and related recovery for children and young adults. It may reflect the growing use of advanced medical therapies in...

Noninvasive fecal calprotectin levels tracked with endoscopic disease activity in children with colonic Crohn's disease, suggesting FC could help reduce repeat endoscopies and better monitor treatment response.

Illness perceptions and perceived ability to understand health information are linked to self-care in IBD. If worse illness perceptions tend to lead to later increases in perceived difficulty understanding written...

Young people with IBD often struggle with health insurance knowledge during transition to adult care. Improving insurance literacy can help them access care and manage coverage decisions. This study suggests a brief,...

If confirmed, a pathology marker visible on routine biopsy (EGC patterns by SOX10 IHC) could help predict which children with ulcerative colitis are more likely to have improved mucosal inflammation over the first year,...

Shows molecular correlates (reduced IL‑17 signaling and IL‑1β) linked with mucosal healing after exclusive enteral nutrition in children with Crohn's disease, which may help researchers develop biomarkers or understand...

Pediatric-onset IBD can behave differently than adult-onset disease. Comparing conventional versus biologic approaches in children may help clarify relative effectiveness, safety, and impacts on growth and steroid...

Reports a rare co-occurrence of SMAS and nutcracker phenomenon in a person with active ulcerative colitis; highlights that weight loss and obstructive symptoms in IBD may have uncommon anatomical causes.

PUC often behaves differently and more aggressively than adult-onset UC; understanding pediatric‑specific causes and treatments could lead to better, more effective therapies for children.

Imaging found increased visceral fat in children with Crohn's despite normal BMI, which could reveal inflammation-related risk not apparent from weight alone. Visceral adiposity was linked to markers of inflammation and...

Monogenic causes (especially IL-10RA mutations) are common in infant-onset IBD and are linked to more severe disease and higher mortality; early genetic testing and consideration of HSCT may change prognosis.

Children with newly diagnosed ulcerative colitis in this study commonly had reduced muscle mass (sarcopenia) at diagnosis, and the degree of muscle loss correlated with higher disease activity and inflammation....

This trial is testing risankizumab in children with moderate-to-severe Crohn’s disease to learn how the drug behaves in kids, whether it’s safe, and whether it reduces disease activity — information that could expand...

Children with IBD and neurodevelopmental disorders may face different perioperative courses after colectomy — notably longer preoperative stays, greater need for nutritional support, and higher risk of postoperative...

A national pediatric IBD registry from Colombia summarizes diagnosis age, disease types, treatment patterns (including rising biologic use), and outcomes—information that can inform families and clinicians about regional...

Obituaries that mention Crohn’s disease can help the IBD community by acknowledging lived experience, caregiving burdens, and directing support to relevant charities. They also humanize long-term disease impact.

This trial tests whether oral vancomycin can help children with atypical ulcerative colitis or PSC-associated colitis and whether changes in gut bacteria or metabolites explain response. If effective and safe, it could...

This trial studies adalimumab safety and pediatric dosing in children with moderate–severe Crohn's disease, which is directly relevant to families and clinicians considering anti-TNF therapy for pediatric IBD.

Work participation and sick leave affect daily life, income, and quality of life for people with IBD. Understanding when sick leave is more common can help patients, employers, and clinicians plan support around...

The study raises the possibility that perinatal exposure to nanoplastics could have lasting, sex-specific effects on gut health and make adult offspring more susceptible to intestinal inflammation. This may be relevant...

The study suggests ADHD and autism are linked with slightly higher risk of more severe IBD events (including need for advanced therapies and, for UC, colectomy), which may help target monitoring and support for young...

Cure8 found this source from Journal of pediatric gastroenterology and nutrition, but the page could not be read reliably yet. It is tagged for Inflammatory bowel disease and Pediatrics and family. Open the original...

Trends in treatments for children with IBD can affect hospitalization and surgical needs. Noting rising use of biologics (infliximab) alongside fewer hospitalizations may be important for families and clinicians tracking...

Psychological distress is common in IBD and often goes unaddressed; a peer-led virtual program could expand access to emotional support and inform larger trials if found feasible and acceptable.

Thalidomide can help treat refractory pediatric IBD but causes peripheral neuropathy. Knowing a cumulative-dose threshold linked to neuropathy could help clinicians balance benefit and neurotoxicity risk.

Differences in urbanisation and socioeconomic development may help explain rising IBD rates in newly industrialised regions and point to where earlier diagnosis and healthcare planning might be needed. The association...

C. difficile can cause or complicate diarrhoea in children with IBD, so understanding test positivity in this group helps clinicians interpret results and decide when to investigate or treat. The study suggests...

Malnutrition and growth failure at diagnosis are common in children with IBD—especially Crohn’s—and can indicate higher inflammatory burden. Monitoring and addressing nutrition and growth is important because most...

Coordinated transition to adult gastroenterology affects continuity of care for children with chronic GI conditions such as IBD; improvements could reduce gaps in treatment and support during young adulthood.

Based on the title and source metadata, this appears to be a patient education related to Inflammatory bowel disease and Pediatrics and family. The original article is from Journal of Pediatric Gastroenterology and...

Patients with CGD can develop an IBD-like condition that is hard to treat because many immunosuppressive drugs raise infection risk. This trial suggests thalidomide may reduce intestinal inflammation in CGD-IBD without...

Persistent fatigue is a common disabling symptom in IBD even during remission; a structured adapted physical activity program could offer a non-drug way to improve daily functioning if the trial shows benefit.

Both EEN and the Crohn’s disease exclusion diet are used to induce remission in children with Crohn’s disease. Evidence that they perform similarly through 52 weeks may help families and clinicians choose the approach...

Switching biologics is a frequent and consequential decision in children with IBD; using TDM and a mechanism‑based approach can help choose whether to optimize, switch within class, or change drug class.

If you or a child had Kawasaki disease, this study suggests there may be a higher long-term chance of certain skin autoimmune conditions (psoriasis, vitiligo) but no clear increase in IBD or several other autoimmune...

Mental health conditions (depression, anxiety, ADHD) appear to increase before and after IBD diagnosis, suggesting psychological care may be needed earlier in the diagnostic pathway and long term.

Physical activity may be a modifiable factor that could improve fitness, inflammation, symptoms like fatigue, and quality of life in children with IBD. This trial will provide objective, randomized data relevant to...

Researchers used machine learning and molecular docking plus small animal tests to link a common plasticizer (DEP) with molecular changes seen in pediatric Crohn’s disease. This could point to environmental exposures...

Art made by someone with Crohn’s disease was publicly recognized and installed in the college president’s office, which can raise awareness and validate patient experiences. The piece also touches on the emotional and...

Clear, reproducible ultrasound definitions for transmural healing and response could help clinicians track deeper intestinal healing beyond mucosal assessment and allow trials to use consistent imaging endpoints.

This study reports that combining an anti-TNF-α drug with vedolizumab helped many children with IBD who failed single-biologic therapy achieve clinical, endoscopic, and histologic improvement. It also notes serious...