Crohn's disease

Extra‑intestinal Crohn’s disease can first appear as chronic vulvar swelling and pain, which may be misdiagnosed in adolescents and young adults.

Noninvasive TUS can help detect small-bowel inflammation and stenosis in Crohn's disease with high specificity, potentially reducing the need for immediate invasive testing. However, its sensitivity varies by small-bowel...

This study could clarify which imaging test—MRE or IUS—is more accurate or appropriate for monitoring treatment response in Crohn's disease, potentially standardising follow-up and informing patient and clinician...

The study indicates that active inflammation—measured by CDAI and PDAI—drives poorer quality of life in Crohn's disease more than the mere presence of fistulas. That shifts focus toward controlling inflammation to...

The review suggests RDW, an inexpensive and widely available blood test parameter, is higher in IBD and correlates with disease activity—meaning it might help clinicians monitor disease alongside other tests.

Vitamin D deficiency is common in people with IBD and may relate to disease activity, complications, and quality of life; understanding this link could influence monitoring and adjunctive care.

NICE’s patient summary explains care expectations for people with Crohn’s disease, emphasising shared decision-making, symptom control, and understanding treatment options — practical points that affect everyday...

Cure8 found this source from youtube.com, but the page could not be read reliably yet. It is tagged for Crohn's disease, Inflammatory bowel disease, and Community and awareness. Open the original article for the full...

Based on the title and source metadata, this appears to be an observational study related to Crohn's disease, Inflammatory bowel disease, and Complications. The original article is from msn.com.

TRPV channels are proposed as integrative mediators of inflammation, angiogenesis, and oxidative stress in IBD, suggesting new mechanistic targets that could eventually yield novel therapies for Crohn's disease and...

Patients with IBD may see TREMFYA appearing more widely as a treatment option and influencing which drugs companies prioritize. Rising sales and trial signals can speed access but don’t replace clinical guidance about...

Older adults with IBD may face different infection risks when treated with advanced biologic therapies. This study aims to compare hospitalizations for serious infections after starting vedolizumab (ENTYVIO) versus TNF...

The record concerns a planned surgical approach using a patient's own bone marrow–derived stem cells to try to heal fistulating perianal Crohn's disease—an often hard-to-treat complication that substantially affects...

Vedolizumab blood levels can vary with disease activity; a model that links intestinal α4β7 expression to drug exposure helps explain why some patients have lower drug levels and may need different dosing. This could...

This study suggests there are distinct molecular subtypes of perianal fistulizing Crohn’s disease, and some subtypes may be more likely to benefit from surgical repair while others have higher inflammatory burden and...

Perianal fistulizing Crohn’s disease causes delayed healing and high recurrence after surgery. This study suggests a specific time-guided external traditional therapy may speed wound healing, reduce inflammation, and...

Local fundraisers both raise money for IBD research/support and help build community and visibility for people living with Crohn’s disease and ulcerative colitis. Hearing personal stories can reduce isolation and point...

For people with perianal Crohn’s disease, better bedside imaging that distinguishes phlegmon from abscess can change surgery plans and may avoid unnecessary wide drainage procedures.

Depression is common in people with Crohn’s disease and can affect quality of life and ability to manage IBD. Knowing prevalence and common symptoms locally helps clinicians and patients recognize and seek appropriate...

This project explores how gut microbes and bile acids interact to shape immune cells in the ileum — a process that may affect inflammation in Crohn’s disease and other IBDs. Understanding these mechanisms could point to...

If surgeons can safely perform a primary bowel reconnection when they encounter an intra-abdominal abscess during Crohn surgery, some patients may avoid a temporary stoma and its associated morbidity.

The study identifies specific induction exposure targets and biomarkers tied to higher chances of deep remission at 12 months in children on anti-TNF therapy, which could inform earlier dose optimization to improve...

People with IBD and their clinicians often worry that anorectal surgery like hemorrhoidectomy could cause complications, flares, or loss of continence. This study suggests that, in a selected multicenter European cohort,...

Dietary changes are common among people with IBD but long-term adherence is low; understanding what patients find acceptable and what barriers they face can help clinicians design practical, culturally sensitive dietary...

The coexistence of Peutz-Jeghers syndrome and Crohn's disease is exceptionally rare, and both conditions carry increased cancer risk. Patients, families, and clinicians need to know that there is little evidence to guide...

Diagnostic delays can mean a child with Crohn's disease doesn't get timely treatment. This report shows weight loss in young patients—especially girls—can be mistakenly labeled an eating disorder, so awareness and...

ECCO 2026 presented multiple studies that could change IBD care across prevention, medical therapy (including pediatric data), complication‑directed strategies (perianal fistula), and technology‑assisted monitoring....

Perianal fistulizing Crohn's disease is difficult to treat and many patients have failed anti-TNF therapy. Evidence that ustekinumab achieves high clinical fistula response and remission rates in a real-world multicenter...

Many people with IBD still experience active disease, poor quality of life, work impairment, and depression even while on advanced therapies — highlighting gaps in how we measure and manage treatment success. Who this...

People with IBD often take biologics and may need or want implant-based breast surgery.

The analysis suggests genetic liability to IBD, particularly Crohn’s disease, may raise the risk of IgA vasculitis. This is relevant for understanding overlapping immune mechanisms and possible shared pathways between...

Understanding which patients are at higher risk for serious complications after IBD surgery can help patients and clinicians weigh risks, plan preoperative optimization, and guide research into preventive strategies.

Lung inflammation can occur in children with IBD but is uncommon and may be hard to spot because symptoms can be vague or absent. Early recognition matters because imaging, bronchoscopy, and sometimes biopsy help...

Kidney dysfunction can occur in people with IBD and may be under-recognized. A validated prediction model could help clinicians identify IBD patients at higher risk and prompt earlier monitoring or interventions.

Intestinal fibrosis (stricture) is a serious, hard-to-treat complication of IBD/Crohn's disease. This preclinical study tests whether an antifibrotic drug used in lung fibrosis might reduce fibrosis in the gut, which...

This study reports real-world outcomes with granulocyte and monocyte adsorptive apheresis (GMA) in patients with refractory IBD, showing steroid-free remission by week 14 in about one-third of patients and continued...

Stoma creation and whether it can later be closed greatly affects daily life and planning for people with Crohn's disease.

Metabolic syndrome appears common in this Tunisian IBD cohort (about one-third). MetS can affect overall health and may influence long-term outcomes for people with IBD, so awareness and cardiometabolic screening may be...

The study suggests a cellular redox pathway (selenium vs thiol axis) that is altered differently in Crohn's disease versus colorectal cancer, which could point to disease vulnerabilities and possible links to treatment...

The study suggests that in IBD the gut microbiome’s functional impact on immune signalling is shifted toward inflammation even when composition appears similar to controls.

Perianal inflammatory lesions are common in Crohn's disease and may mark higher cancer-related risk; knowing their association with worse survival after anorectal cancer surgery can inform discussions about prognosis and...

Findings are relevant because they describe outcomes and predictors of conversion for a minimally invasive surgery option (SILS) that some patients with Crohn's disease may be offered. Understanding risk factors can help...

Elevated pancreatic enzymes are relatively common in IBD and can reflect very different conditions (benign asymptomatic elevations, pancreatitis variants, or autoimmune pancreatitis). Recognizing phenotype-specific...

Based on the title and source metadata, this appears to be a clinical study related to Crohn's disease, Inflammatory bowel disease, and Tests and monitoring. The original article is from Journal of Crohn's & colitis.

This paper describes a new engineered, off-the-shelf regulatory T cell therapy (TRX103) designed to restore immune tolerance and that is already entering early clinical trials for treatment-refractory Crohn’s disease.

Sarcopenia is common in Crohn's disease and is linked to worse outcomes; a simple GNRI-based prediction tool could help identify at-risk patients without routine CT scanning.

Infliximab dosing can be hard to personalize. This study shows that selecting pharmacokinetic models based on IBD type and severity can improve how well drug levels are predicted, which could help tailor dosing for...

Perianal fistulas are a serious complication of Crohn’s disease with limited high-quality trial evidence. This randomized trial suggests ustekinumab may increase the chance of combined clinical and MRI remission at 12...