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Articles for parents and caregivers navigating pediatric IBD news, family decisions, school issues, and child health updates.

Page 5 of 7 · 307 articles

Health-Related quality of life in Russian children with inflammatory bowel disease is comparable across disease types and treatment modalities
Frontiers in Pediatrics

Health-Related quality of life in Russian children with inflammatory bowel disease is comparable across disease types and treatment modalities

The paper suggests that HRQoL and family functioning may be similar across disease types and common treatment approaches in children with IBD, but emotional health and parental worry remain areas needing attention.

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The ImproveCareNow Registry: Prediction of remission rates in paediatric Crohn's disease.
Journal of pediatric gastroenterology and nutrition

The ImproveCareNow Registry: Prediction of remission rates in paediatric Crohn's disease.

Patients, families, and clinicians can use registry-based predictors to better understand which children with Crohn’s disease may be at higher risk of slower or absent remission, which could inform monitoring and...

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Latent profile analysis of fertility motivation in women with inflammatory bowel disease: a cross-sectional study
BMC Women s Health

Latent profile analysis of fertility motivation in women with inflammatory bowel disease: a cross-sectional study

Decisions about having children are common and sometimes complex for women living with IBD. This study maps different motivation patterns and the factors linked to them, which could help clinicians tailor reproductive...

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ĐẶC ĐIỂM RỐI LOẠN TRẦM CẢM Ở NGƯỜI BỆNH CROHN ĐIỀU TRỊ TẠI TRUNG TÂM TIÊU HÓA- GAN MẬT BỆNH VIỆN BẠCH MAI
Tạp chí Y học Cộng đồng

ĐẶC ĐIỂM RỐI LOẠN TRẦM CẢM Ở NGƯỜI BỆNH CROHN ĐIỀU TRỊ TẠI TRUNG TÂM TIÊU HÓA- GAN MẬT BỆNH VIỆN BẠCH MAI

Depression is common in people with Crohn’s disease and can affect quality of life and ability to manage IBD. Knowing prevalence and common symptoms locally helps clinicians and patients recognize and seek appropriate...

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Pharmacometric Targets During Anti-TNF Induction and Their Association with Deep Remission in Pediatric Crohn’s Disease
Clinical Pharmacokinetics

Pharmacometric Targets During Anti-TNF Induction and Their Association with Deep Remission in Pediatric Crohn’s Disease

The study identifies specific induction exposure targets and biomarkers tied to higher chances of deep remission at 12 months in children on anti-TNF therapy, which could inform earlier dose optimization to improve...

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The safe and effective use of tofacitinib and ustekinumab combination therapy in infantile onset inflammatory bowel disease.
JPGN reports

The safe and effective use of tofacitinib and ustekinumab combination therapy in infantile onset inflammatory bowel disease.

The report suggests tofacitinib (a JAK inhibitor), alone or combined with ustekinumab, could be an effective option for some infants with treatment-refractory IOIBD — a population with few evidence-based alternatives. If...

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A joint transdisciplinary approach for paediatric inflammatory bowel disease: Integrating nursing, dietetic and psychological support.
JPGN reports

A joint transdisciplinary approach for paediatric inflammatory bowel disease: Integrating nursing, dietetic and psychological support.

Integrated joint appointments could make it easier for children with IBD and their families to get coordinated care for symptoms, nutrition, and mental health in a single visit, which may improve access and reduce stigma...

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Very early onset inflammatory bowel disease in Jordan: a single-center case series of clinical, genetic, and therapeutic features
BMC Pediatrics

Very early onset inflammatory bowel disease in Jordan: a single-center case series of clinical, genetic, and therapeutic features

VEOIBD often has a strong genetic component and different clinical needs than adult IBD; this study shows genetic findings and treatment challenges in a Middle East pediatric center, which may affect diagnosis and access...

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Is it always necessary to wait until day 5 for second line treatment in children with acute severe ulcerative colitis?
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

Is it always necessary to wait until day 5 for second line treatment in children with acute severe ulcerative colitis?

If reliable, an earlier day‑3 PUCAI cutoff could help identify children with flare‑related ASUC who are unlikely to respond to IV steroids and who may benefit from earlier planning for second‑line therapy rather than...

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Lymphocyte-C-Reactive Protein Ratio as Promising New Marker for Predicting Surgical Site Infection in Children With Ulcerative Colitis.
Annals of gastroenterological surgery

Lymphocyte-C-Reactive Protein Ratio as Promising New Marker for Predicting Surgical Site Infection in Children With Ulcerative Colitis.

A simple blood ratio measured before surgery (LCR) may help predict which children with UC are at higher risk of surgical site infection after IPAA, potentially guiding preoperative care.

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The genetic landscape of congenital diarrheas and very early onset inflammatory bowel disease in the Middle East.
JPGN reports

The genetic landscape of congenital diarrheas and very early onset inflammatory bowel disease in the Middle East.

Finding monogenic causes in infants with congenital diarrheas or VEOIBD can directly affect diagnosis, genetic counseling, and management. Populations with higher consanguinity may have higher diagnostic yields for...

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An Overview of the Rationale and Outcomes of Residential Camps for Children with Inflammatory Bowel Disease.
Pediatric gastroenterology, hepatology & nutrition

An Overview of the Rationale and Outcomes of Residential Camps for Children with Inflammatory Bowel Disease.

Children with IBD commonly experience emotional and social challenges; residential camps appear to improve quality of life, confidence, disease knowledge, and reduce isolation, making them relevant as a supportive,...

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Reactive Therapeutic Drug Monitoring Guides Optimal Management of Adalimumab Failure in Pediatric Crohn's Disease: A Real-World Single-Center Experience.
Pediatric gastroenterology, hepatology & nutrition

Reactive Therapeutic Drug Monitoring Guides Optimal Management of Adalimumab Failure in Pediatric Crohn's Disease: A Real-World Single-Center Experience.

Reactive TDM can help determine why a child with Crohn's disease is losing response to adalimumab and guide whether to escalate dose or switch biologics, which affects short-term management decisions.

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A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis
ClinicalTrials.gov

A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

This trial explores whether oral ozanimod can induce and maintain remission in children and adolescents with moderate to severe ulcerative colitis who have not responded to standard therapies. Pediatric-specific evidence...

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Transitional care in pediatric inflammatory bowel disease: current strategies and future directions - a narrative review.
Przeglad gastroenterologiczny

Transitional care in pediatric inflammatory bowel disease: current strategies and future directions - a narrative review.

Transition from pediatric to adult IBD care is a high-risk period; structured programs and better communication can improve adherence and reduce relapse and hospitalization risk for young people with IBD.

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Assessment of kinesiophobia in ulcerative colitis: a case-control study highlighting functional and psychological implications.
Revista da Associacao Medica Brasileira (1992)

Assessment of kinesiophobia in ulcerative colitis: a case-control study highlighting functional and psychological implications.

Fear of movement was more common and more severe in people with ulcerative colitis in this study. Addressing kinesiophobia could help increase physical activity and improve function and quality of life for people with...

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Remission duration according to dietary adherence in paediatric mild to moderate Crohn's disease treated with CDED + PEN.
Przeglad gastroenterologiczny

Remission duration according to dietary adherence in paediatric mild to moderate Crohn's disease treated with CDED + PEN.

Dietary therapy (CDED + PEN) was associated with longer remission when families adhered well; since adherence varies, support from a dietitian matters for keeping children in remission.

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Subcutaneous infliximab in pediatric inflammatory bowel disease: Sustained remission, predictable pharmacokinetics, and real-world US implementation.
Journal of pediatric gastroenterology and nutrition

Subcutaneous infliximab in pediatric inflammatory bowel disease: Sustained remission, predictable pharmacokinetics, and real-world US implementation.

Subcutaneous infliximab could offer children with IBD a more convenient dosing route with higher, steadier drug levels while maintaining remission. Insurance and labeling barriers affected access in this US cohort.

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Disorders of Gut-Brain Interaction like symptoms in Children with Inflammatory Bowel Disease: A Multicenter Prospective Study from the Pediatric IBD Porto Group of the ESPGHAN.
The American journal of gastroenterology

Disorders of Gut-Brain Interaction like symptoms in Children with Inflammatory Bowel Disease: A Multicenter Prospective Study from the Pediatric IBD Porto Group of the ESPGHAN.

Children with IBD can have persistent gut–brain interaction symptoms even when inflammation is quiescent; these symptoms are linked with worse quality of life and higher anxiety. Recognizing DGBI-like symptoms may help...

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Exclusive enteral nutrition containing transforming growth factor‐β improves intestinal barrier function in a colitis mouse model
Journal of Pediatric Gastroenterology and Nutrition

Exclusive enteral nutrition containing transforming growth factor‐β improves intestinal barrier function in a colitis mouse model

The study investigates how components of exclusive enteral nutrition (EEN), particularly transforming growth factor‑β (TGF‑β), may help restore intestinal barrier function after colitis. That could help explain why EEN...

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Cryptogenic Multifocal Ulcerating Stenosing Enteritis (CMUSE) in a Patient with Down Syndrome: A Case Report
Reports — Medical Cases Images and Videos

Cryptogenic Multifocal Ulcerating Stenosing Enteritis (CMUSE) in a Patient with Down Syndrome: A Case Report

CMUSE can closely mimic Crohn's disease and may require surgery for diagnosis and symptom relief. Recognizing it can change diagnostic pathways and multidisciplinary management for people with recurrent small-bowel...

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The ‘Cross‐Trust’ Histopathology Multidisciplinary Team: Report of meeting outputs and impact on paediatric inflammatory bowel disease management in a UK tertiary centre
JPGN Reports

The ‘Cross‐Trust’ Histopathology Multidisciplinary Team: Report of meeting outputs and impact on paediatric inflammatory bowel disease management in a UK tertiary centre

A cross‑trust histopathology MDT helped reclassify diagnoses in a substantial proportion of discussed paediatric IBD cases and occasionally changed management or transition planning, which could affect treatment...

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Meta-analysis: safety and efficacy of ustekinumab in pediatric inflammatory bowel disease patients with anti-TNF failure.
BMC gastroenterology

Meta-analysis: safety and efficacy of ustekinumab in pediatric inflammatory bowel disease patients with anti-TNF failure.

This review pools available pediatric data showing ustekinumab can induce and maintain remission after anti‑TNF failure, offering a treatment option for children with refractory IBD. Results are most robust for Crohn’s...

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Ulcerative colitis with a mutation in the HMBS gene associated with acute intermittent porphyria
Experimental and Clinical Gastroenterology

Ulcerative colitis with a mutation in the HMBS gene associated with acute intermittent porphyria

Finding a pathogenic HMBS variant in a child with extensive ulcerative colitis suggests rare genetic conditions (like acute intermittent porphyria) can appear alongside or mimic IBD and might affect symptoms or...

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Comparative performance of intestinal ultrasound activity indices in pediatric ulcerative colitis: a prospective study.
Journal of Crohn's & colitis

Comparative performance of intestinal ultrasound activity indices in pediatric ulcerative colitis: a prospective study.

Noninvasive monitoring matters for children with UC because endoscopy is burdensome. If ultrasound (and simple measures like bowel wall thickness) can reliably detect moderate-to-severe disease, families may avoid some...

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Proactive therapeutic drug monitoring of infliximab leads to treatment durability in paediatric Crohn's disease: A single‐centre Australian experience
JPGN Reports

Proactive therapeutic drug monitoring of infliximab leads to treatment durability in paediatric Crohn's disease: A single‐centre Australian experience

Proactive TDM of infliximab was associated with high 1‑ and 2‑year durability in this pediatric Crohn's cohort, and the study flags clinical factors that may predict need to switch biologics. This could be relevant when...

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The shifting burden of early-onset inflammatory bowel disease: a global analysis.
Pediatric research

The shifting burden of early-onset inflammatory bowel disease: a global analysis.

The study shows that more children worldwide are living with early-onset IBD even as mortality has fallen, and it highlights persistent socioeconomic disparities—important for families and clinicians tracking pediatric...

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Subcutaneous infliximab as a maintenance option in pediatric IBD: a real-world cohort including younger and lower-weight children.
Molecular and cellular pediatrics

Subcutaneous infliximab as a maintenance option in pediatric IBD: a real-world cohort including younger and lower-weight children.

Subcutaneous infliximab may let children on infliximab avoid regular IV infusions while keeping drug levels high and maintaining remission. Results are relevant to families and clinicians considering switching pediatric...

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Diagnostic performance of fecal eosinophil-derived neurotoxin and lipocalin-2 in pediatric inflammatory bowel disease
BMC Gastroenterology

Diagnostic performance of fecal eosinophil-derived neurotoxin and lipocalin-2 in pediatric inflammatory bowel disease

Cure8 found this source from BMC Gastroenterology, but the page could not be read reliably yet. It is tagged for Inflammatory bowel disease and Tests and monitoring. Open the original article for the full details.

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Atopic Dermatitis and Risk of Inflammatory Bowel Disease in Children: A Systematic Review and Meta-Analysis
Cureus

Atopic Dermatitis and Risk of Inflammatory Bowel Disease in Children: A Systematic Review and Meta-Analysis

This review found that children with atopic dermatitis have a modestly higher risk of later developing IBD (both Crohn’s disease and ulcerative colitis). Awareness of this association may help clinicians and families...

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Presentation and Clinical Outcomes of Inflammatory Bowel Disease in Children and Adolescents at a Tertiary Care Center in Lebanon.
Journal of clinical medicine

Presentation and Clinical Outcomes of Inflammatory Bowel Disease in Children and Adolescents at a Tertiary Care Center in Lebanon.

This study describes how IBD presents and early outcomes in children at a tertiary center, noting high rates of inflammation, nutritional problems, and early flares. Findings may help families and clinicians understand...

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Inflammatory Bowel Disease and Its Unique Impact on Body Image: A Qualitative Exploration.
Journal of clinical psychology

Inflammatory Bowel Disease and Its Unique Impact on Body Image: A Qualitative Exploration.

Body-image concerns in IBD are linked with poorer mental health, eating behaviours, and overall quality of life. Understanding these experiences can help clinicians and support services better address emotional and...

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Impact of pediatric vs. adult diagnosed IBD on achievement of health care autonomy in emerging adults: a cross-sectional study
Crohn s & Colitis 360

Impact of pediatric vs. adult diagnosed IBD on achievement of health care autonomy in emerging adults: a cross-sectional study

Emerging adults with IBD face distinct challenges managing care. The study shows people diagnosed as children may know about their disease but still need help with practical self-management tasks — a gap that can affect...

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Clinical indications and outcomes of pediatric gastrointestinal endoscopy in a resource-limited healthcare system: Findings from the first multicenter study
PubMed Central

Clinical indications and outcomes of pediatric gastrointestinal endoscopy in a resource-limited healthcare system: Findings from the first multicenter study

Endoscopy in this pediatric multicenter series found a high diagnostic yield and confirmed IBD and other treatable conditions; this matters for families and clinicians in resource-limited settings because improving...

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Real-world patterns of inflammatory bowel disease treatment across adult and pediatric populations: a nationwide cohort study in South Korea
Frontiers in Medicine

Real-world patterns of inflammatory bowel disease treatment across adult and pediatric populations: a nationwide cohort study in South Korea

Patients, families, and clinicians may care because the study shows pediatric-onset IBD is more often Crohn's and that children begin advanced therapies earlier than adults. The adult persistence data for vedolizumab and...

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A Study to Assess the Pharmacokinetics, Effectiveness and Safety of Afimkibart for Induction and Maintenance Therapy in Children With Moderately to Severely Active Crohn's Disease
ClinicalTrials.gov

A Study to Assess the Pharmacokinetics, Effectiveness and Safety of Afimkibart for Induction and Maintenance Therapy in Children With Moderately to Severely Active Crohn's Disease

A successful Phase 3 trial could provide a new treatment option specifically studied in children with moderate‑to‑severe Crohn's disease, addressing a pediatric population often underrepresented in trials.

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