Resection, ostomy, J-pouch, strictureplasty, fistula, abscess, and other procedure-related updates.
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Quality of life is often substantially affected in IBD; this study identifies active disease, greater severity, prior surgery, and stricturing Crohn's disease as factors linked to lower HRQoL, highlighting areas...
The article reports a new oral nanozyme that combines imaging and ROS-scavenging therapy aimed at IBD lesions—an early-stage approach that could one day enable targeted, noninvasive treatment and lesion tracking.
If validated, AI-enhanced vascular assessment during endoscopy could give clearer, more reproducible information about mucosal and histologic healing — which matters for monitoring disease activity and guiding treatment...
This report describes combined use of upadacitinib and ustekinumab to treat severe, refractory perianal Crohn’s disease in an adolescent — a scenario many patients and caregivers find especially difficult to manage.
This case shows that routine pre-biologic screening can reveal other granulomatous disease (pulmonary sarcoidosis) that may affect treatment choice. It also illustrates that infliximab (an anti-TNF) was used with...
Perianal fistulas in Crohn’s disease are often hard to treat; this review suggests stem cell therapies can produce durable closure for many patients and appear safe over 1–4 years of follow-up.
A dedicated Digestive Health Centre could make it easier for people with IBD (including children and teens) to access coordinated care—fewer separate visits and more centralized specialist services in one location.
A Meckel diverticulum can present like Crohn’s disease and may be the true cause when IBD treatment fails; identifying it can lead to a surgical cure for symptoms such as anemia and obstruction.
AI-assisted detection tools and disease-specific optical classifications could improve lesion detection and real-time characterization during UC surveillance, potentially affecting surveillance accuracy and...
Perianal fistulas are a common, hard-to-heal complication of Crohn's disease. This review collects current options beyond infliximab and explains where evidence is stronger or still emerging, which can help patients and...
The case links thymic hyperplasia, thyroid autoimmunity, and severe UC with colorectal neoplasia, suggesting possible shared immune dysregulation that might interest patients and clinicians, but it does not support...
Fistula-associated adenocarcinoma is a rare but serious long-term complication of Crohn’s disease that can be missed because symptoms overlap with benign disease. Awareness can prompt timely diagnostic evaluation when...
The study shows pouchitis is a frequent postoperative problem in children after RPC‑IPAA and that many will still require advanced IBD medications, so surgery may not end medical therapy needs.
Consistent, accurate endoscopic scoring matters for treatment decisions and trial outcomes in pediatric IBD. If focused training meaningfully improves scoring—especially for SES‑CD—it could reduce variability in clinical...
Researchers are exploring ways to durably modulate macrophages in ulcerative colitis because persistent pro-inflammatory macrophages sustain tissue inflammation and impair healing.
Based on the title and source metadata, this appears to be a case report related to Ulcerative colitis and Procedures and surgery. The original article is from Gastrointestinal endoscopy.
Atypical presentations of Crohn's disease (abdominal wall abscess with enterocutaneous fistula) can delay diagnosis and treatment in children. Patients with communication difficulties may be at higher risk for missed or...
Based on the title and source metadata, this appears to be a video related to Crohn's disease, Inflammatory bowel disease, and Procedures and surgery. The original article is from hmpgloballearningnetwork.com.
Based on the title and source metadata, this appears to be a case report related to Ulcerative colitis, Inflammatory bowel disease, and Ustekinumab. The original article is from Immunological Medicine.
People with Crohn’s disease and prior bowel surgeries may face different risks and trade-offs when choosing prostate cancer treatment. A multidisciplinary, patient-centered approach helped this patient avoid additional...
Based on the title and source metadata, this appears to be a patient education related to Ulcerative colitis, Inflammatory bowel disease, and Procedures and surgery. The original article is from Baylor University Medical...
Perianal fistulising Crohn's disease is hard to treat and often fails anti-TNF drugs. This study will provide real-world data on whether upadacitinib can be effective and safe for patients with refractory perianal...
Cure8 found this source from bioengineer.org, but the page could not be read reliably yet. It is tagged for Crohn's disease, Inflammatory bowel disease, and Procedures and surgery. Open the original article for the full...
Researchers used clustering on mixed clinical and treatment data to identify distinct Crohn's disease course trajectories and a small high-burden subgroup. If validated, such trajectories might help inform prognosis and...
Based on the title and source metadata, this appears to be a patient education related to Fistula and Procedures and surgery. The original article is from scirp.org.
This systematic review focuses on two ways surgeons reconnect the bowel after minimally invasive right-sided surgery for Crohn’s disease. It found fewer overall postoperative complications with intracorporeal anastomosis...
A direct-vision push-type dilator (BougieCap) was used to safely dilate a low rectal stricture from Crohn's disease, allowing same-session sigmoidoscopy and biopsy and reported symptom improvement up to 18 months.
Automated, validated grading of UC on colonoscopy images could reduce variability between endoscopists and help standardize severity assessment that influences treatment planning.
A reproducible animal model of perianal fistulizing Crohn’s disease could help researchers study how fistulas form and persist and provide a test platform for new therapies before human trials.
Malnutrition was common in this group and linked to lower fistula healing and a higher chance of needing proctectomy or abdominal surgery — outcomes that matter to people with perianal Crohn’s disease.
Refractory IBD in children is linked to growth and development problems, hospitalizations, and surgery; knowing treatment options after anti‑TNF failure matters for long‑term outcomes. The review highlights which...
A pro athlete’s experience with perianal Crohn’s disease shows how chronic pain and major surgery can disrupt training and life, and offers practical strategies (advocacy, rehab, pacing) that other people with IBD may...
This study directly compares two rescue medications used when intravenous steroids fail in acute severe ulcerative colitis, reporting similar short-term remission and safety but a slower early response with tacrolimus —...
Based on the title and source metadata, this appears to be a case report related to Inflammatory bowel disease and Procedures and surgery. The original article is from ACG case reports journal.
Fibrotic strictures in Crohn’s disease often don’t respond to medication and may need endoscopic or surgical treatment. This trial directly compares two endoscopic options to see which is safer and more effective at...
A new oral investigational drug (TP317) is entering a Phase 1b study in adults with active UC to assess safety and pharmacokinetics, which may be relevant to patients seeking information about emerging therapies.
Strictures cause obstructive symptoms and repeat surgery in Crohn’s disease; endoscopic options can relieve obstruction and potentially avoid or postpone surgery for some patients.
Findings describe how often and when dysplasia recurs after ESD for UC-associated neoplasia, information that can affect decisions about endoscopic treatment versus colectomy and surveillance planning.
Predicting which children with Crohn disease will need surgery — and roughly when — could help families and clinicians plan treatments, monitoring, and discussions about elective bowel resection earlier in the disease...
A non-invasive MRI method that correlates with histology and endoscopic scores could reduce the need for frequent colonoscopy for assessing IBD activity and help monitor treatment response, especially when endoscopy is...
If MSCs can limit ferroptosis via CBS, that points to a new biological pathway that might be targeted to reduce intestinal inflammation in Crohn's disease. This could guide future lab research and eventually early-phase...
Understanding how patient-derived epithelial cells respond to inflammation could reveal mechanisms of poor mucosal healing in IBD and identify targets or biomarkers to improve repair. Organoid models from patient tissue...
Many people with IBD have ongoing IBS-like symptoms despite little or no intestinal inflammation. This project targets brain–gut and autonomic mechanisms that might explain symptom persistence and tests a non-drug...
This project describes a novel off-the-shelf engineered regulatory T cell therapy aiming to promote intestinal immune regulation and mucosal healing — a different approach than current biologics. If successful, it could...
Long-term results suggest endoscopic approaches—especially balloon dilatation—help many people with Crohn’s strictures avoid surgery and have fewer severe complications compared with surgical treatment.
The study suggests starting anti-TNF therapy with an immunomodulator at diagnosis may reduce surgery, hospital stays, and progression to complicated Crohn’s over 5 years — outcomes that matter to patients and clinicians...
Shifting care toward disease modification could reduce long-term bowel damage and disability for people with Crohn's disease by prioritizing earlier, more effective treatment and exploring prevention strategies.
Based on the title and source metadata, this appears to be a video related to Inflammatory bowel disease and Procedures and surgery. The original article is from hmpgloballearningnetwork.com.
