Resection, ostomy, J-pouch, strictureplasty, fistula, abscess, and other procedure-related updates.
Page 4 of 11 · 490 articles
The study presents a cell-free EV therapy that reduced inflammation in an experimental colitis model by reprogramming dendritic cells, which could inform future IBD treatments. It highlights a specific immunoregulatory...
This study suggests routine restriction of oral intake during IBD flares (without obstruction/abscess/fistula) is common but not linked to better short-term outcomes, so unnecessary fasting may be avoidable for many...
Setons are often used to control sepsis in complex anal fistula, but this study suggests outcomes are worse when Crohn's disease is present, meaning clinicians may view long-term setons as temporary measures in CD rather...
The findings give clinicians and patients data on how often biologic therapy leads to endoscopic remission in biologic‑naïve patients with isolated small‑bowel Crohn's disease, and they suggest similar effectiveness...
Noninvasive detection of intestinal fibrosis activity could help identify patients at risk of progressive scarring and surgery, and enable development or targeting of anti-fibrotic treatments for Crohn's disease.
This trial tests whether starting with one biologic or targeted therapy versus another (and the sequence of switches) affects remission, safety, and quality of life for people with moderate-to-severe ulcerative colitis —...
If you're living with Crohn's disease, earlier and better diagnosis (for example, more cross-sectional imaging) may partly explain falling surgery rates over time. This study suggests system-level diagnostic improvements...
The analysis compares rescue drugs used when severe ulcerative colitis doesn't respond to IV steroids — a high-stakes situation where avoiding colectomy matters.
Postoperative endoscopic recurrence is common after ileocolonic resection for Crohn’s disease; this study suggests biologic drugs started after surgery are linked to lower recurrence rates. Knowing which biologics...
Postoperative recurrence is common after intestinal resection for Crohn's disease, but clinicians currently lack reliable molecular biomarkers or validated models to predict who will relapse.
This study addresses whether continuing advanced biologic therapies around abdominal surgery raises short-term postoperative risks—important for IBD patients and clinicians planning surgery.
Patients and surgeons weighing robotic versus laparoscopic IPAA for ulcerative colitis may care because the study suggests similar short-term complication rates between approaches in this cohort, which could inform...
Baseline MRE features may help predict which Crohn's strictures will not improve with advanced medical therapy, informing monitoring and surgical planning. Better stratification could guide decisions about earlier...
Based on the title and source metadata, this appears to be a video related to Inflammatory bowel disease and Procedures and surgery. The original article is from hmpgloballearningnetwork.com.
This trial tests a novel, tissue-derived cell therapy applied directly to intestinal ulcers — an approach that could lead to new local healing treatments for people with Crohn’s disease if proven safe and effective.
Surgery is still a core part of care for certain UC and Crohn's patients despite better medical therapies. Newer surgical techniques and coordinated medical–surgical approaches aim to reduce complications and recurrence...
Chronic antibiotic-refractory pouchitis is a common, impactful complication after ileal pouch-anal anastomosis that can worsen quality of life and increase the risk of pouch failure. Patients and clinicians need clearer...
A decreasing need for IBD-related surgery after pediatric diagnosis could mean fewer major operations and related recovery for children and young adults. It may reflect the growing use of advanced medical therapies in...
The study aims to map the specific peptide targets of T cells driving organ inflammation in autoimmune diseases, which could guide development of antigen-specific, tolerogenic treatments relevant to Crohn's disease and...
Perianal skin damage from diarrhea (IAD) is common and painful in active Crohn's disease. A combined skin-protection plus individualized nutrition approach was associated with lower IAD rates, less pain, and faster...
Extraintestinal manifestations (skin, joint, eye, liver) are common in IBD and can greatly affect quality of life; better recognition and coordinated care can speed diagnosis and improve outcomes.
Macrophages are central regulators of intestinal inflammation and repair; understanding their diversity and how to modulate them could lead to new, more targeted treatments for Crohn's disease and ulcerative colitis.
Reports a rare co-occurrence of SMAS and nutcracker phenomenon in a person with active ulcerative colitis; highlights that weight loss and obstructive symptoms in IBD may have uncommon anatomical causes.
Endoscopic scores guide detection and treatment of postoperative Crohn's recurrence; better scoring could change who gets earlier therapy and potentially prevent clinical or surgical relapse.
Persistent or worsening colonic dilatation in ulcerative colitis can reflect severe, possibly irreversible bowel‑wall damage even when classic signs of toxic megacolon are absent. Recognizing this may prompt timely...
Surgeons and other clinicians managing IBD patients need to understand current biologic and immunomodulator options, their risks, and implications for surgical timing and perioperative care.
Cure8 found this source from Gastroenterology report, but the page could not be read reliably yet. It is tagged for Ulcerative colitis, Inflammatory bowel disease, and JAK inhibitor. Open the original article for the...
If you have isolated perianal fistulizing Crohn’s disease, this large multicenter cohort shows about one-third later developed luminal Crohn’s disease over long-term follow-up, but many did not — underscoring variable...
Monogenic causes (especially IL-10RA mutations) are common in infant-onset IBD and are linked to more severe disease and higher mortality; early genetic testing and consideration of HSCT may change prognosis.
People with Crohn’s disease who develop kidney failure sometimes face limited dialysis options. This paper suggests peritoneal dialysis may work for some patients—especially those in sustained remission—but also shows...
The 5-year PROFILE follow-up is presented as strong evidence that early, effective therapy (in this case infliximab plus an immunomodulator) can change the long-term course of Crohn’s disease by lowering surgery rates...
If donor ethnicity or specific microbial/metabolite signatures influence FMT success, results could help identify optimal donors or develop targeted microbiota-based treatments for ulcerative colitis.
This analysis directly addresses treatments commonly used for perianal fistulizing Crohn’s disease and compares biologic anti-TNF drugs with emerging mesenchymal stem cell therapy, information that could affect treatment...
Low muscle mass before ileocolic resection appears linked to higher short-term surgical complications and higher rates of endoscopic recurrence — information that could affect preoperative assessment and planning for...
Trials testing intestinal ultrasound–guided treat-to-target strategies and late-stage therapies could change how Crohn’s disease is monitored and treated if they show improved outcomes.
Knowing a patient’s estimated infliximab clearance before starting rescue therapy for acute severe ulcerative colitis could help identify who may need higher or intensified induction dosing and who might be at greater...
ITB can closely mimic Crohn’s disease, so this study is relevant because it describes diagnostic test yields and illustrates that targeted TB testing and therapeutic trials of antituberculosis treatment can help...
People with IBD who need shoulder replacement may face higher short-term risks after surgery, including infections, pneumonia, sepsis, emergency visits, and a greater chance of needing revision operations. Knowing this...
Appendiceal phlegmon and fistulization can produce focal terminal ileal changes that look like Crohn’s disease on imaging and endoscopy; recognizing this can prevent misdiagnosis.
Trends in treatments for children with IBD can affect hospitalization and surgical needs. Noting rising use of biologics (infliximab) alongside fewer hospitalizations may be important for families and clinicians tracking...
This registry could collect real-world outcome data about hyperbaric oxygen therapy for many conditions that sometimes overlap with IBD care (Crohn’s disease, ulcerative colitis, pouchitis, rectovaginal fistula).
Fistulas between the intestine and bladder are a serious, though uncommon, complication of long‑standing Crohn’s disease and often require surgery. Robotic, minimally invasive approaches may allow complex resections and...
Malnutrition is common and can worsen outcomes in IBD; this case shows use of combined enteral and parenteral nutritional support for severe malnutrition in newly diagnosed Crohn’s disease, including perioperative...
Based on the title and source metadata, this appears to be a case report related to Crohn's disease, Inflammatory bowel disease, and Procedures and surgery. The original article is from Baylor University Medical Center...
This trial tests standardized encapsulated fecal microbiota products as a microbiome-directed therapy for active Crohn’s disease, focusing on whether donor microbes engraft in the ileum and colon and whether that relates...
Dysplasia detection during colonoscopy is central to preventing colorectal cancer in people with IBD. AI tools could help, but current models often fail in inflamed or IBD-specific settings, so this review outlines...
Nurse-led, protocolized care can make delivery of complex biologic and small-molecule IBD treatments safer and more consistent.
Researchers are exploring ways to improve cell therapies for IBD by making therapeutic cells produce anti-inflammatory molecules like IL-10. If scalable and safe, non-viral engineering of MSCs could lead to...
