Fatigue affects more than half of people with IBD and is a leading cause of impaired quality of life. A machine-learning approach that identifies distinct patient-level patterns may help researchers and clinicians...

Based on the title and source metadata, this appears to be a clinical study related to Crohn's disease, Inflammatory bowel disease, and Research and clinical trials. The original article is from Gastroenterology &...

Based on the title and source metadata, this appears to be a patient education related to Crohn's disease, Inflammatory bowel disease, and Tests and monitoring. The original article is from Gastroenterology & hepatology.

The study suggests a probiotic–ω‑3 combination (a synbiotic) might boost the anti‑inflammatory, pro‑resolving effects of ω‑3s in colonic tissue—potentially relevant for people with ulcerative colitis looking for adjunct...

IL-22 links microbial metabolites to epithelial repair and inflammation; clarifying these pathways could inform future therapies or dietary/microbiome approaches to promote mucosal healing without worsening inflammation.

The paper presents a validated lab method to detect and quantify enantiomeric impurities in upadacitinib, which supports drug quality and safety for patients treated with JAK‑1 inhibitors for IBD and other conditions.

This review highlights a new, non-live microbiome-based therapy approach (probiotic-derived EVs) that could in future modulate gut immunity and barrier function without using live microbes. For people with IBD, such...

Real-world 52-week data suggest mirikizumab can produce meaningful remission and reasonable drug persistence in patients with treatment-experienced ulcerative colitis. This is especially relevant for people who have not...

Simple, routinely measured nutritional scores were associated with early (14-week) remission on vedolizumab in patients with moderate-to-severe UC, which could help identify patients more likely to respond early to this...

Patients with hidradenitis suppurativa have higher baseline IBD risk, and IL-17 inhibitors are effective HS treatments. People with Crohn’s disease or ulcerative colitis (or those at risk) may worry whether these drugs...

The study links a specific gut microbe and its metabolite to reduced inflammation and improved barrier function in ulcerative colitis models and cohort comparisons, suggesting a potential new microbiome-targeted therapy...

People with IBD who need shoulder replacement may face higher short-term risks after surgery, including infections, pneumonia, sepsis, emergency visits, and a greater chance of needing revision operations. Knowing this...

Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Biomarkers. The original article is from Biochemia medica.

The study suggests ADHD and autism are linked with slightly higher risk of more severe IBD events (including need for advanced therapies and, for UC, colectomy), which may help target monitoring and support for young...

Cure8 found this source from Journal of pediatric gastroenterology and nutrition, but the page could not be read reliably yet. It is tagged for Inflammatory bowel disease and Pediatrics and family. Open the original...

Older adults (≥60) with IBD are an increasing population worldwide, and IBD-related anemia is rising—this affects screening needs, healthcare planning, and resource allocation. The findings point to widening...

Appendiceal phlegmon and fistulization can produce focal terminal ileal changes that look like Crohn’s disease on imaging and endoscopy; recognizing this can prevent misdiagnosis.

Patients who present with new radiologic terminal ileitis sometimes develop Crohn’s disease. Identifying simple blood and imaging markers that predict who is at higher risk could help prioritize follow-up or specialist...

The study proposes a new redox-regulatory pathway (Grx1–STAT6) that helps M2 macrophages drive tissue repair and colitis recovery in preclinical models, pointing to a possible new therapeutic target to promote...

This study suggests that a confirmed Campylobacter stool infection in people with IBD was followed by higher rates of flare and need for treatment escalation within 12 months, so infected patients might need closer...

Patients cared for in accredited IBD units reported better experience and higher satisfaction in this study, which suggests that accreditation may improve patient-centred aspects of care even if self-reported disease...

A validated Spanish IBD-Disk gives Spanish-speaking patients and clinicians a brief, validated tool to measure disability and global health in IBD, supporting consistent monitoring and research across Spanish-speaking...

Patients with moderate-to-severe Crohn's disease who do not respond to anti-TNF drugs have limited options. This study suggests combining ustekinumab with upadacitinib may improve endoscopic healing versus either drug...

Trends in treatments for children with IBD can affect hospitalization and surgical needs. Noting rising use of biologics (infliximab) alongside fewer hospitalizations may be important for families and clinicians tracking...

Better endoscopic classification of flat-type dysplasia could improve surveillance accuracy for people with long-standing ulcerative colitis, helping identify lesions that need biopsy or more urgent management.

If a panenteric capsule can replace colonoscopy plus small-bowel imaging for initial diagnosis, it could offer a less invasive, single-test pathway for many people suspected of having Crohn's disease. That may reduce the...

This trial describes a large Phase 3 extension study collecting long-term safety and tolerability data for tulisokibart (MK-7240), an investigational TL1A-targeting antibody for Crohn’s disease and ulcerative colitis....

Psychological distress is common in IBD and often goes unaddressed; a peer-led virtual program could expand access to emotional support and inform larger trials if found feasible and acceptable.

This registry could collect real-world outcome data about hyperbaric oxygen therapy for many conditions that sometimes overlap with IBD care (Crohn’s disease, ulcerative colitis, pouchitis, rectovaginal fistula).

This trial tests an oral live biotherapeutic (MH002) aimed at restoring a healthier gut microbiome in people with mild-to-moderate ulcerative colitis. If effective and safe, it would offer a non-immunosuppressive,...

Fistulas between the intestine and bladder are a serious, though uncommon, complication of long‑standing Crohn’s disease and often require surgery. Robotic, minimally invasive approaches may allow complex resections and...

Malnutrition is common and can worsen outcomes in IBD; this case shows use of combined enteral and parenteral nutritional support for severe malnutrition in newly diagnosed Crohn’s disease, including perioperative...

Thalidomide can help treat refractory pediatric IBD but causes peripheral neuropathy. Knowing a cumulative-dose threshold linked to neuropathy could help clinicians balance benefit and neurotoxicity risk.

Differences in urbanisation and socioeconomic development may help explain rising IBD rates in newly industrialised regions and point to where earlier diagnosis and healthcare planning might be needed. The association...

The findings highlight that older adults are less likely to be prescribed advanced IBD therapies, which could reflect prescribing patterns, comorbidities, insurance factors, or access issues relevant to treatment...

Identifies a molecule (CCL3) linked to more severe inflammation in IBD tissues, which could help researchers develop new biomarkers or treatments targeting immune-cell recruitment and polarization.

The study proposes a new oral nanoparticle that targets neutrophil-driven oxidative stress linked to mucosal barrier damage, a mechanism relevant to IBD pathology. If translatable, this approach could add a new modality...

The study suggests higher dietary antioxidant intake (measured by CDAI) may be linked to lower Crohn's disease risk and that inflammation biomarkers could partly explain the association—information potentially relevant...

The study describes a targeted oral delivery system for 5-ASA that aims to concentrate drug release in the colon and also leverage inulin’s prebiotic/immunomodulatory properties—potentially improving effectiveness and...

Depression is common in Crohn’s disease and appears linked to immune and microbial signals from the gut. Understanding gut–brain mechanisms could improve how mood symptoms are detected and treated in people with IBD.

Targeted oral delivery of melatonin could reduce inflammation and help repair the intestinal barrier in UC by acting on macrophages and epithelial cells. If translated to humans, this approach might offer a locally...

AMPs are central to gut immune balance and are being explored as new therapies for IBD and related gut diseases. For people with Crohn’s or IBD, understanding AMPs helps explain research directions aimed at restoring...

The study connects a bothersome UC symptom (bowel urgency) to intestinal ultrasound signs of transmural inflammation, suggesting ultrasound might help explain and track symptom-related inflammation without relying solely...

SRCEUS may offer higher-resolution, noninvasive assessment of intestinal microvascular changes that correspond to Crohn disease activity, which could improve monitoring and reduce reliance on invasive tests.

Based on the title and source metadata, this appears to be an opinion or commentary related to Crohn's disease, Inflammatory bowel disease, and Tests and monitoring. The original article is from Radiology.

Identifies a stromal-cell subset marked by TIMP1 that may play a role in UC pathogenesis and might serve as a candidate biomarker or therapeutic target; useful for researchers and clinicians following emerging...

Cure8 found this source from auntminnie.com, but the page could not be read reliably yet. It is tagged for Crohn's disease, Inflammatory bowel disease, and Tests and monitoring. Open the original article for the full...

Better automated scoring tools for endoscopic images could reduce variability between human reviewers and help standardize assessments of ulcerative colitis severity used for treatment decisions and monitoring.