Crohn's disease

Medication adherence affects how well IBD maintenance treatment works. This study highlights the everyday challenges and beliefs that shape whether people stick with prescribed therapies, which can help clinicians and...

Many people with IBD change their diets and avoid foods they believe trigger flares. Differences between Crohn’s disease and ulcerative colitis were observed, and many—especially those with UC—reported not receiving...

Cure8 could only read part of this source from dermatologytimes.com, so this card uses cautious topic tags instead of a full summary. It is tagged for Crohn's disease and Complications.

Art made by someone with Crohn’s disease was publicly recognized and installed in the college president’s office, which can raise awareness and validate patient experiences. The piece also touches on the emotional and...

Vitamin D deficiency is common in people with IBD and this study suggests correcting deficiency may help rebalance immune cells and the microbiome—potentially supporting inflammation control alongside standard...

Iliopsoas abscess is an uncommon but serious penetrating complication of Crohn’s disease that can present with non-specific symptoms and be missed. The review compiles case-level evidence about presentation, diagnosis,...

People with Crohn’s who have had ileal or ileocolic surgery often worry about needing another operation; this study seeks clinical and biomarker predictors to estimate that risk. Understanding predictors could help...

Patients and clinicians often seek adjunctive options to improve symptoms, quality of life, or reduce treatment burden. This trial tests whether Bacillus spore probiotics added to standard care can provide measurable...

Mapping microbes and metabolites directly from different gut regions could reveal location-specific changes linked to IBD activity and help researchers develop better biomarkers or targeted treatments.

Faster, reliable reading of capsule endoscopy videos could shorten diagnostic delays and make small-bowel evaluation easier for people with suspected Crohn’s disease. If AI preserves accuracy while reducing review time,...

If you or your clinician are using upadacitinib for Crohn’s, intestinal ultrasound early in treatment may help predict who will not respond and who is more likely to relapse on maintenance dosing, potentially guiding...

If confirmed, a simple calprotectin test on fistula scrapings could help predict which Crohn’s patients are likely to heal after primary surgical fistula closure and which may need additional therapies, potentially...

Clear, reproducible ultrasound definitions for transmural healing and response could help clinicians track deeper intestinal healing beyond mucosal assessment and allow trials to use consistent imaging endpoints.

Identifies mast-cell–derived IL-13 as a likely contributor to intestinal fibrosis in Crohn disease, a complication not reliably prevented by current anti-inflammatory treatments. The finding points to a specific immune...

This study helps set expectations about short-term risks after right-sided segmental colectomy for Crohn's disease compared with colon cancer. Knowing that overall complication rates were similar but infections were more...

The study suggests that in some people with IBD who have Candida overgrowth, systemic antifungal therapy (fluconazole) can change gut microbes and metabolites in ways linked to better disease activity over 8 weeks. That...

This study reports that combining an anti-TNF-α drug with vedolizumab helped many children with IBD who failed single-biologic therapy achieve clinical, endoscopic, and histologic improvement. It also notes serious...

This gives families and clinicians a non‑TNF biologic option on‑label for children aged 2+ with moderate‑to‑severe ulcerative colitis, which can change insurance conversations and expand treatment choices for kids who...

This study maps cell types in newly diagnosed pediatric Crohn's and links diagnostic cell patterns to disease severity and anti‑TNF treatment response. That could help predict which children are likely to benefit from...

Ileal pouch disorders are common after IPAA surgery and cause symptoms many patients will experience. Early recognition and initial treatment by primary care can speed symptom relief and identify patients who need...

Based on the title and source metadata, this appears to be an opinion or commentary related to Crohn's disease, Inflammatory bowel disease, and Complications. The original article is from Reumatologia.

This study explores genetic risk variants (NOD2/CARD15) and local environmental factors (khat use) among young adults with IBD in Djibouti — information that may help explain regional differences in Crohn’s disease and...

Label changes for RENFLEXIS affect people with Crohn's disease or ulcerative colitis who take (or may be prescribed) infliximab biosimilars — the label includes dosing, age indications, and important safety warnings that...

Market and late-stage trial updates can indicate which new therapies may become available and influence treatment options, access, and research priorities for Crohn's disease over the coming years.

A cellular atlas that links diagnostic biopsy cell states to treatment outcomes could help predict which children are likely to have severe or anti‑TNF‑resistant Crohn's disease, informing future research on personalized...

This study maps cell-level signatures in newly diagnosed pediatric Crohn’s and links them to later severity and responses to anti-TNF treatment, which could help predict which children will respond to biologic therapy...

This matters because many patients and clinics face procurement-driven switches from reference biologics to biosimilars; early evidence here suggests short-term outcomes and treatment persistence are similar after...

Cure8 could only read part of this source from bdtonline.com, so this card uses cautious topic tags instead of a full summary. It is tagged for Crohn's disease, Inflammatory bowel disease, and Community and awareness.

The FDA approval expands an approved biologic option (ustekinumab/Stelara) to children aged two and older with moderately to severely active ulcerative colitis, giving families and clinicians another treatment choice. It...

First-person stories show the real-life impact of Crohn’s: unpredictable flares, surgeries (including ileostomy), and long recovery can affect education, work, and mental health. Hearing recovery and remission are...

Identifying baseline cellular states that predict disease course or response to anti‑TNF could help researchers develop predictive biomarkers and new therapeutic strategies for pediatric Crohn’s disease.

IBD patients sometimes have low iron or zinc and may try supplements. This trial tested whether two phytase-containing dietary supplements are acceptable and whether they change iron and zinc absorption in adults with...

A new oral drug, LMT503, is entering first-in-human testing for people with Crohn's disease and ulcerative colitis. Early-phase trials establish safety and how the body handles a drug—important first steps before any...

This narrative review surveys novel biomarkers and therapeutic strategies for adult IBD, topics that could affect diagnosis, monitoring, and future treatment options for people with Crohn's disease or ulcerative colitis.

The review found higher ultra-processed food intake was linked to increased odds of Crohn’s disease relapse — a potentially actionable signal because diet can be changed. However, the evidence certainty is very low, so...

Mental health symptoms are common in people with IBD and may be influenced by both psychological and biological factors. A virtual, group psychotherapy program tailored to IBD could increase access to treatment and help...

Sleep timing and morning light are modifiable, nonpharmacologic factors that could influence IBD quality of life and symptoms. If effective, a simple at-home light therapy could be an accessible adjunct to usual care.

This trial tests a novel cell-derived extracellular vesicle therapy (DB-3Q) for people with Crohn’s disease who have not responded to standard advanced therapies. It may offer a different biologic approach if proven safe...

This observational study aims to link nutritional status and the dietary inflammatory potential to IBD activity and to test whether simple blood-derived inflammatory indices can serve as noninvasive markers of disease...

This study looks at how immunomodulators are actually used with biologic drugs in real-world practice when a national reimbursement policy forces biologic interruptions.

Researchers are investigating circRNAs as potential biomarkers and therapeutic targets in IBD because they may help explain disease mechanisms and lead to better diagnostics or treatments in the future.

Depressive symptoms during remission were associated with worse long-term physical, mental, and disease-specific quality of life, so attending to mental health can matter for overall wellbeing in IBD.

Growth impairment is a key concern in pediatric Crohn's disease; knowing which children are more likely to regain weight or height and how treatments like infliximab relate to growth can affect monitoring and treatment...

The study outlines a strategy to target corticosteroids to inflamed intestinal tissue by exploiting PLA2 overexpression, which could reduce systemic steroid side effects if the approach translates to biological models...

This review directly compares surgery-first versus biologic-first strategies for localized ileocaecal Crohn's disease and suggests early resection can lower later treatment needs and leave some patients off medication,...

Imaging and endoscopy can give different pictures of disease activity in newly diagnosed pediatric Crohn’s disease. That matters because treatment decisions often rely on how active disease appears and where it’s...

Based on the title and source metadata, this appears to be a clinical study related to Crohn's disease and Procedures and surgery. The original article is from Urology Video Journal.

Digital health tools could offer more continuous monitoring and self-management support for people with IBD, potentially helping detect flares earlier and improve quality of life. This review collects existing evidence...