Condition
Ulcerative colitis news across medications, symptoms, monitoring, procedures, research, access, and daily life.
Page 20 of 40 · 1920 articles
Delays in diagnosing IBD are common and can raise the risk of complications, so understanding when to push for testing matters. The article explains tests and differences between IBS and IBD to help people know when to...
Researchers present a small platelet-related gene signature (TRIM22, TIMP1, RAC2) that may help understand UC biology and point toward blood-based biomarkers. If validated further, such markers might aid noninvasive...
PSC is closely linked with IBD (especially ulcerative colitis); understanding mechanisms that damage bile ducts could point to new future therapies or biomarkers.
If you or a patient is about to start infliximab for ulcerative colitis, routine blood counts may help identify those unlikely to respond to induction therapy; a high negative predictive value suggests these markers...
The study suggests that modifiable early-life factors (feeding, antibiotic exposure, activity, BMI, smoke exposure, delivery mode, diet) may influence the later risk of IBD, especially Crohn's disease, which could be...
The study suggests a traditional Chinese medicine formula can reduce disease signs in a mouse model of chronic relapsing ulcerative colitis and that its effects are mediated by changes in the gut microbiota and microbial...
Researchers are exploring ways to prioritize who needs colonoscopy sooner; adding TCM features to prediction models might change triage performance. Patients and clinicians interested in pre-endoscopic risk tools or...
This registered randomized trial tests whether adding a specific intradermal acupuncture method to standard mesalazine treatment helps people with mild–moderately active ulcerative colitis reach clinical remission.
This trial tests a non-drug way (virtual reality medical-hypnosis content) to reduce pain and embarrassment during rectosigmoidoscopy — a common, sometimes poorly tolerated procedure in ulcerative colitis that patients...
A dietary multi-mineral supplement is being tested in a Phase 2 trial to see if it can improve symptoms, influence inflammation biomarkers, and help induce or maintain remission in people with ulcerative colitis.
The study targets macrophage mitochondrial dysfunction, a mechanism linked to inflammation in ulcerative colitis, and demonstrates a nanodelivery approach that reduced colitis in mice—an approach that could inspire new...
A JAK inhibitor (upadacitinib) used for moderate–severe ulcerative colitis can cause neutropenia; this case report discusses how it was identified and managed, which matters for patients on the drug and clinicians...
This analysis suggests enteral nutrition may be more effective than a low-residue diet for clinical response in adults with ulcerative colitis and that some dietary strategies may raise albumin, but the underlying trial...
The study suggests a natural seaweed-derived polysaccharide could modify gut bacteria and immune signaling in ways that reduced experimental colitis, which may interest people looking for microbiota-targeted dietary...
Cure8 found this source from Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, but the page could not be read reliably yet....
Endometriosis may coexist with IBD and can cause pelvic pain, painful sex, and heavy periods—symptoms that may be mistaken for bowel disease activity. Identifying endometriosis could change evaluation and management for...
This preclinical study suggests a traditional medicinal plant extract may reduce inflammation and tissue damage in an experimental model of ulcerative colitis, which could guide future drug-discovery research relevant to...
The study suggests a dietary/prebiotic compound (2'-FL) can change gut microbes and patient-reported disease control in mild-to-moderate UC, which could point to non-drug ways to support symptoms and microbiome health.
The study points to specific immune pathways (especially Th17 differentiation) and molecular targets that might explain DSP’s anti-inflammatory effects in ulcerative colitis, which could guide further preclinical and...
Researchers used laboratory mouse and cell models to show that total glucosides of paeony (TGP) may reduce inflammation linked to ulcerative colitis and identified molecular pathways (COX‑2/arachidonic acid, NF‑κB, MAPK,...
TL1A-DR3 is implicated in both inflammation and fibrosis in IBD, so targeting it could address active disease and reduce fibrotic complications that lead to strictures. New TL1A-blocking antibodies are already in...
Researchers describe a natural peptide that binds IL‑17RA and reduced disease measures in mouse colitis models — a potential new mechanism for reducing gut inflammation and restoring the epithelial barrier that could...
This study describes a new oral peptide hydrogel that, in mouse models, appears to reduce colitis severity by acting on both immune signaling (TLR4) and the gut microbiome. For people with UC, treatments that target both...
New or late-stage drugs from a major company can change future treatment options and availability for people with IBD. J&J’s pipeline mentions several programs specifically targeting ulcerative colitis and Crohn’s...
Surveillance colonoscopies in IBD are meant to detect dysplasia or cancer; this report shows some solitary polyps may be benign retention polyps. Correct endoscopic removal and pathology spare patients from unnecessary...
Vitamin D deficiency was common among Albanian patients with IBD and showed a weak inverse association with disease activity in ulcerative colitis, suggesting vitamin D status may relate to symptom burden or...
This trial tests whether an oral S1P modulator (etrasimod) is more effective than standard mesalazine for inducing remission in adults with active UC — a question that could affect initial treatment choices in China.
This study will collect real-world data on etrasimod, an oral S1P receptor modulator, in people with ulcerative colitis, using patient-reported symptom measures over one year — information that may help patients and...
A pediatric Phase 2 trial testing etrasimod could expand treatment options for children with moderately to severely active ulcerative colitis if later shown safe and effective. Families of affected children and their...
The study identifies a molecular link between epithelial mitochondrial oxidative stress and NLRP3-driven inflammation in ulcerative colitis models, suggesting a possible new target for research into disease mechanisms...
Growth and nutrition are common concerns in children with IBD because poor weight gain and short stature can affect long‑term health and development.
Cure8 found this source from Journal of paediatrics and child health, but the page could not be read reliably yet. It is tagged for Ulcerative colitis, Inflammatory bowel disease, and Upadacitinib. Open the original...
This paper explores whether individualized integrative management including traditional Chinese medicine might influence outcomes in patients with biologic‑refractory, surgery‑intended acute severe ulcerative colitis — a...
The study points to three bile-acid–related genes that may be linked to inflammation in ulcerative colitis and could serve as biomarkers or targets for future research into disease mechanisms and patient stratification.
The study links TXNIP/NLRP3 inflammatory signaling to disease features in an animal UC model and tests engeletin and rosuvastatin as interventions that lowered inflammatory markers—information relevant to researchers...
Colon-targeted delivery systems aim to concentrate drugs in the colon, which could improve effectiveness and reduce systemic side effects for IBD and colorectal cancer treatments. Understanding these approaches helps...
The study links activation of the cGAS–STING immune-sensing pathway to NF-κB–driven inflammation and tumor formation in UC models, which could help explain mechanisms behind colitis-associated colorectal cancer risk.
The work aims to predict relapse and personalize herbal maintenance dosing for UC, which matters because better risk stratification and tailored management could reduce relapses and avoid unnecessary treatment changes.
This animal study suggests date palm pollen extract reduced inflammation and tissue damage in a rat model of colitis, which could point to new lines of research into dietary supplements or natural compounds for gut...
Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and CRP. The original article is from Alimentary Pharmacology & Therapeutics.
Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Crohn's disease, and Inflammatory bowel disease. The original article is from Alimentary Pharmacology &...
Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Community and awareness. The original article is from Iraqi Journal of Pharmacy.
The study links a common plant compound (oxalate) to higher stool levels and worse inflammation in IBD, suggesting diet and gut handling of oxalate could affect disease activity and that microbiome-targeted strategies...
This study reports a new herbal hydrogel designed to repair the intestinal barrier, shift gut microbes, and modulate immune signals (IL-22/IL-34) in preclinical models of ulcerative colitis—ideas that could inform future...
Adding a mesalazine retention enema to oral mesalazine improved short-term symptom relief and endoscopic signs of mucosal healing in mild-to-moderate left-sided ulcerative colitis in this retrospective study. That could...
Blood biomarkers that predict vedolizumab response could help patients and clinicians choose the most effective therapy sooner and avoid ineffective treatments. The study suggests LRG and MCP‑1 may differentiate...
If you have moderate–severe ulcerative colitis, this study suggests that typical phase III trials may exclude more than half of patients seen in specialty clinics, which can make trial results less representative of...
The paper identifies a potential microbiome–metabolite–PKC pathway by which an herbal formula reduced colonic injury in a rat model of UC; this could point to new targets for research into mucosal repair and...
