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Pediatrics and family

Children, teens, growth, school, parents, caregivers, and family-centered IBD updates.

Page 7 of 8 · 377 articles

Proactive therapeutic drug monitoring of infliximab leads to treatment durability in paediatric Crohn's disease: A single‐centre Australian experience
JPGN Reports

Proactive therapeutic drug monitoring of infliximab leads to treatment durability in paediatric Crohn's disease: A single‐centre Australian experience

Proactive TDM of infliximab was associated with high 1‑ and 2‑year durability in this pediatric Crohn's cohort, and the study flags clinical factors that may predict need to switch biologics. This could be relevant when...

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The shifting burden of early-onset inflammatory bowel disease: a global analysis.
Pediatric research

The shifting burden of early-onset inflammatory bowel disease: a global analysis.

The study shows that more children worldwide are living with early-onset IBD even as mortality has fallen, and it highlights persistent socioeconomic disparities—important for families and clinicians tracking pediatric...

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Subcutaneous infliximab as a maintenance option in pediatric IBD: a real-world cohort including younger and lower-weight children.
Molecular and cellular pediatrics

Subcutaneous infliximab as a maintenance option in pediatric IBD: a real-world cohort including younger and lower-weight children.

Subcutaneous infliximab may let children on infliximab avoid regular IV infusions while keeping drug levels high and maintaining remission. Results are relevant to families and clinicians considering switching pediatric...

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Diagnostic performance of fecal eosinophil-derived neurotoxin and lipocalin-2 in pediatric inflammatory bowel disease
BMC Gastroenterology

Diagnostic performance of fecal eosinophil-derived neurotoxin and lipocalin-2 in pediatric inflammatory bowel disease

Cure8 found this source from BMC Gastroenterology, but the page could not be read reliably yet. It is tagged for Inflammatory bowel disease and Tests and monitoring. Open the original article for the full details.

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Atopic Dermatitis and Risk of Inflammatory Bowel Disease in Children: A Systematic Review and Meta-Analysis
Cureus

Atopic Dermatitis and Risk of Inflammatory Bowel Disease in Children: A Systematic Review and Meta-Analysis

This review found that children with atopic dermatitis have a modestly higher risk of later developing IBD (both Crohn’s disease and ulcerative colitis). Awareness of this association may help clinicians and families...

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Presentation and Clinical Outcomes of Inflammatory Bowel Disease in Children and Adolescents at a Tertiary Care Center in Lebanon.
Journal of clinical medicine

Presentation and Clinical Outcomes of Inflammatory Bowel Disease in Children and Adolescents at a Tertiary Care Center in Lebanon.

This study describes how IBD presents and early outcomes in children at a tertiary center, noting high rates of inflammation, nutritional problems, and early flares. Findings may help families and clinicians understand...

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Inflammatory Bowel Disease and Its Unique Impact on Body Image: A Qualitative Exploration.
Journal of clinical psychology

Inflammatory Bowel Disease and Its Unique Impact on Body Image: A Qualitative Exploration.

Body-image concerns in IBD are linked with poorer mental health, eating behaviours, and overall quality of life. Understanding these experiences can help clinicians and support services better address emotional and...

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Impact of pediatric vs. adult diagnosed IBD on achievement of health care autonomy in emerging adults: a cross-sectional study
Crohn s & Colitis 360

Impact of pediatric vs. adult diagnosed IBD on achievement of health care autonomy in emerging adults: a cross-sectional study

Emerging adults with IBD face distinct challenges managing care. The study shows people diagnosed as children may know about their disease but still need help with practical self-management tasks — a gap that can affect...

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Clinical indications and outcomes of pediatric gastrointestinal endoscopy in a resource-limited healthcare system: Findings from the first multicenter study
PubMed Central

Clinical indications and outcomes of pediatric gastrointestinal endoscopy in a resource-limited healthcare system: Findings from the first multicenter study

Endoscopy in this pediatric multicenter series found a high diagnostic yield and confirmed IBD and other treatable conditions; this matters for families and clinicians in resource-limited settings because improving...

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Real-world patterns of inflammatory bowel disease treatment across adult and pediatric populations: a nationwide cohort study in South Korea
Frontiers in Medicine

Real-world patterns of inflammatory bowel disease treatment across adult and pediatric populations: a nationwide cohort study in South Korea

Patients, families, and clinicians may care because the study shows pediatric-onset IBD is more often Crohn's and that children begin advanced therapies earlier than adults. The adult persistence data for vedolizumab and...

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A Study to Assess the Pharmacokinetics, Effectiveness and Safety of Afimkibart for Induction and Maintenance Therapy in Children With Moderately to Severely Active Crohn's Disease
ClinicalTrials.gov

A Study to Assess the Pharmacokinetics, Effectiveness and Safety of Afimkibart for Induction and Maintenance Therapy in Children With Moderately to Severely Active Crohn's Disease

A successful Phase 3 trial could provide a new treatment option specifically studied in children with moderate‑to‑severe Crohn's disease, addressing a pediatric population often underrepresented in trials.

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Linking Clinical Disease Activity to Quality of Life in Ulcerative Colitis: Serial Mediation by Patient Activation and Comfort.

This study shows that patients' comfort partly explains how clinical disease activity affects quality of life in ulcerative colitis, suggesting comfort-focused nursing care could help patients feel better even when...

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Novel SLC10A2 variants induce primary bile acid malabsorption and dysbiosis with IBD-like features.
Inflammatory bowel diseases

Novel SLC10A2 variants induce primary bile acid malabsorption and dysbiosis with IBD-like features.

Genetic primary bile acid malabsorption can produce IBD-like symptoms and may be missed in children labeled with Crohn's disease; recognizing PBAM could change testing and management for some patients.

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