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Pediatrics and family

Children, teens, growth, school, parents, caregivers, and family-centered IBD updates.

Page 6 of 8 · 377 articles

Health-Related quality of life in Russian children with inflammatory bowel disease is comparable across disease types and treatment modalities
Frontiers in Pediatrics

Health-Related quality of life in Russian children with inflammatory bowel disease is comparable across disease types and treatment modalities

The paper suggests that HRQoL and family functioning may be similar across disease types and common treatment approaches in children with IBD, but emotional health and parental worry remain areas needing attention.

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The ImproveCareNow Registry: Prediction of remission rates in paediatric Crohn's disease.
Journal of pediatric gastroenterology and nutrition

The ImproveCareNow Registry: Prediction of remission rates in paediatric Crohn's disease.

Patients, families, and clinicians can use registry-based predictors to better understand which children with Crohn’s disease may be at higher risk of slower or absent remission, which could inform monitoring and...

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Latent profile analysis of fertility motivation in women with inflammatory bowel disease: a cross-sectional study
BMC Women s Health

Latent profile analysis of fertility motivation in women with inflammatory bowel disease: a cross-sectional study

Decisions about having children are common and sometimes complex for women living with IBD. This study maps different motivation patterns and the factors linked to them, which could help clinicians tailor reproductive...

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ĐẶC ĐIỂM RỐI LOẠN TRẦM CẢM Ở NGƯỜI BỆNH CROHN ĐIỀU TRỊ TẠI TRUNG TÂM TIÊU HÓA- GAN MẬT BỆNH VIỆN BẠCH MAI
Tạp chí Y học Cộng đồng

ĐẶC ĐIỂM RỐI LOẠN TRẦM CẢM Ở NGƯỜI BỆNH CROHN ĐIỀU TRỊ TẠI TRUNG TÂM TIÊU HÓA- GAN MẬT BỆNH VIỆN BẠCH MAI

Depression is common in people with Crohn’s disease and can affect quality of life and ability to manage IBD. Knowing prevalence and common symptoms locally helps clinicians and patients recognize and seek appropriate...

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Pharmacometric Targets During Anti-TNF Induction and Their Association with Deep Remission in Pediatric Crohn’s Disease
Clinical Pharmacokinetics

Pharmacometric Targets During Anti-TNF Induction and Their Association with Deep Remission in Pediatric Crohn’s Disease

The study identifies specific induction exposure targets and biomarkers tied to higher chances of deep remission at 12 months in children on anti-TNF therapy, which could inform earlier dose optimization to improve...

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The safe and effective use of tofacitinib and ustekinumab combination therapy in infantile onset inflammatory bowel disease.
JPGN reports

The safe and effective use of tofacitinib and ustekinumab combination therapy in infantile onset inflammatory bowel disease.

The report suggests tofacitinib (a JAK inhibitor), alone or combined with ustekinumab, could be an effective option for some infants with treatment-refractory IOIBD — a population with few evidence-based alternatives. If...

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A joint transdisciplinary approach for paediatric inflammatory bowel disease: Integrating nursing, dietetic and psychological support.
JPGN reports

A joint transdisciplinary approach for paediatric inflammatory bowel disease: Integrating nursing, dietetic and psychological support.

Integrated joint appointments could make it easier for children with IBD and their families to get coordinated care for symptoms, nutrition, and mental health in a single visit, which may improve access and reduce stigma...

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Very early onset inflammatory bowel disease in Jordan: a single-center case series of clinical, genetic, and therapeutic features
BMC Pediatrics

Very early onset inflammatory bowel disease in Jordan: a single-center case series of clinical, genetic, and therapeutic features

VEOIBD often has a strong genetic component and different clinical needs than adult IBD; this study shows genetic findings and treatment challenges in a Middle East pediatric center, which may affect diagnosis and access...

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Is it always necessary to wait until day 5 for second line treatment in children with acute severe ulcerative colitis?
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

Is it always necessary to wait until day 5 for second line treatment in children with acute severe ulcerative colitis?

If reliable, an earlier day‑3 PUCAI cutoff could help identify children with flare‑related ASUC who are unlikely to respond to IV steroids and who may benefit from earlier planning for second‑line therapy rather than...

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Lymphocyte-C-Reactive Protein Ratio as Promising New Marker for Predicting Surgical Site Infection in Children With Ulcerative Colitis.
Annals of gastroenterological surgery

Lymphocyte-C-Reactive Protein Ratio as Promising New Marker for Predicting Surgical Site Infection in Children With Ulcerative Colitis.

A simple blood ratio measured before surgery (LCR) may help predict which children with UC are at higher risk of surgical site infection after IPAA, potentially guiding preoperative care.

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Single-Incision Laparoscopy-First Strategy in Crohn's Disease: Risk Factors for Conversion and Surgical Outcomes.
Annals of gastroenterological surgery

Single-Incision Laparoscopy-First Strategy in Crohn's Disease: Risk Factors for Conversion and Surgical Outcomes.

Findings are relevant because they describe outcomes and predictors of conversion for a minimally invasive surgery option (SILS) that some patients with Crohn's disease may be offered. Understanding risk factors can help...

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The genetic landscape of congenital diarrheas and very early onset inflammatory bowel disease in the Middle East.
JPGN reports

The genetic landscape of congenital diarrheas and very early onset inflammatory bowel disease in the Middle East.

Finding monogenic causes in infants with congenital diarrheas or VEOIBD can directly affect diagnosis, genetic counseling, and management. Populations with higher consanguinity may have higher diagnostic yields for...

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A Specific Probiotic in thE MOdulation of Gut Microbiota of patieNts With Mild-to-modErate Ulcerative Colitis
ClinicalTrials.gov

A Specific Probiotic in thE MOdulation of Gut Microbiota of patieNts With Mild-to-modErate Ulcerative Colitis

This trial is testing whether a rectally delivered probiotic can change the gut microbiome and promote mucosal healing in people with mild-to-moderate ulcerative colitis (and includes some Crohn's patients). If...

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An Overview of the Rationale and Outcomes of Residential Camps for Children with Inflammatory Bowel Disease.
Pediatric gastroenterology, hepatology & nutrition

An Overview of the Rationale and Outcomes of Residential Camps for Children with Inflammatory Bowel Disease.

Children with IBD commonly experience emotional and social challenges; residential camps appear to improve quality of life, confidence, disease knowledge, and reduce isolation, making them relevant as a supportive,...

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Reactive Therapeutic Drug Monitoring Guides Optimal Management of Adalimumab Failure in Pediatric Crohn's Disease: A Real-World Single-Center Experience.
Pediatric gastroenterology, hepatology & nutrition

Reactive Therapeutic Drug Monitoring Guides Optimal Management of Adalimumab Failure in Pediatric Crohn's Disease: A Real-World Single-Center Experience.

Reactive TDM can help determine why a child with Crohn's disease is losing response to adalimumab and guide whether to escalate dose or switch biologics, which affects short-term management decisions.

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Case Report: A rare adult case of ELANE-related severe congenital neutropenia revealed by neutropenic enterocolitis.
Frontiers in immunology

Case Report: A rare adult case of ELANE-related severe congenital neutropenia revealed by neutropenic enterocolitis.

An ELANE mutation causing severe congenital neutropenia can present with neutropenic enterocolitis that mimics ulcerative colitis. Recognizing neutropenia and pursuing genetic testing can prevent misdiagnosis and change...

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A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis
ClinicalTrials.gov

A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

This trial explores whether oral ozanimod can induce and maintain remission in children and adolescents with moderate to severe ulcerative colitis who have not responded to standard therapies. Pediatric-specific evidence...

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Transitional care in pediatric inflammatory bowel disease: current strategies and future directions - a narrative review.
Przeglad gastroenterologiczny

Transitional care in pediatric inflammatory bowel disease: current strategies and future directions - a narrative review.

Transition from pediatric to adult IBD care is a high-risk period; structured programs and better communication can improve adherence and reduce relapse and hospitalization risk for young people with IBD.

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Assessment of kinesiophobia in ulcerative colitis: a case-control study highlighting functional and psychological implications.
Revista da Associacao Medica Brasileira (1992)

Assessment of kinesiophobia in ulcerative colitis: a case-control study highlighting functional and psychological implications.

Fear of movement was more common and more severe in people with ulcerative colitis in this study. Addressing kinesiophobia could help increase physical activity and improve function and quality of life for people with...

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Association between life satisfaction and selected socio-demographic factors and social and professional activity - a comparative study between patients with Crohn's disease and patients with ulcerative colitis.
Przeglad gastroenterologiczny

Association between life satisfaction and selected socio-demographic factors and social and professional activity - a comparative study between patients with Crohn's disease and patients with ulcerative colitis.

Life satisfaction and social/work impacts are central to daily functioning for people with IBD. Knowing which social factors relate to lower satisfaction can help patients, caregivers, and clinicians spot who may need...

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Remission duration according to dietary adherence in paediatric mild to moderate Crohn's disease treated with CDED + PEN.
Przeglad gastroenterologiczny

Remission duration according to dietary adherence in paediatric mild to moderate Crohn's disease treated with CDED + PEN.

Dietary therapy (CDED + PEN) was associated with longer remission when families adhered well; since adherence varies, support from a dietitian matters for keeping children in remission.

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Subcutaneous infliximab in pediatric inflammatory bowel disease: Sustained remission, predictable pharmacokinetics, and real-world US implementation.
Journal of pediatric gastroenterology and nutrition

Subcutaneous infliximab in pediatric inflammatory bowel disease: Sustained remission, predictable pharmacokinetics, and real-world US implementation.

Subcutaneous infliximab could offer children with IBD a more convenient dosing route with higher, steadier drug levels while maintaining remission. Insurance and labeling barriers affected access in this US cohort.

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Translation and Spanish validation of the Quality of Life Questionnaire for patients with perianal fistula in Crohn's disease (Sp CAF-QoL Scale).
Revista espanola de enfermedades digestivas

Translation and Spanish validation of the Quality of Life Questionnaire for patients with perianal fistula in Crohn's disease (Sp CAF-QoL Scale).

Perianal fistulas in Crohn's disease significantly affect quality of life, and this study provides an initially validated Spanish tool to measure that impact, enabling better assessment in Spanish-speaking patients and...

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Disorders of Gut-Brain Interaction like symptoms in Children with Inflammatory Bowel Disease: A Multicenter Prospective Study from the Pediatric IBD Porto Group of the ESPGHAN.
The American journal of gastroenterology

Disorders of Gut-Brain Interaction like symptoms in Children with Inflammatory Bowel Disease: A Multicenter Prospective Study from the Pediatric IBD Porto Group of the ESPGHAN.

Children with IBD can have persistent gut–brain interaction symptoms even when inflammation is quiescent; these symptoms are linked with worse quality of life and higher anxiety. Recognizing DGBI-like symptoms may help...

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Inflammatory Bowel Disease and Periprosthetic Joint Infection Following Total Joint Arthroplasty: Crohn's Disease and Ulcerative Colitis Associated With Varying Risk.
Arthroplasty today

Inflammatory Bowel Disease and Periprosthetic Joint Infection Following Total Joint Arthroplasty: Crohn's Disease and Ulcerative Colitis Associated With Varying Risk.

Patients with Crohn's disease had a higher adjusted risk of periprosthetic joint infection within 90 days after elective joint replacement, while ulcerative colitis did not. This difference could affect preoperative risk...

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Exclusive enteral nutrition containing transforming growth factor‐β improves intestinal barrier function in a colitis mouse model
Journal of Pediatric Gastroenterology and Nutrition

Exclusive enteral nutrition containing transforming growth factor‐β improves intestinal barrier function in a colitis mouse model

The study investigates how components of exclusive enteral nutrition (EEN), particularly transforming growth factor‑β (TGF‑β), may help restore intestinal barrier function after colitis. That could help explain why EEN...

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Cryptogenic Multifocal Ulcerating Stenosing Enteritis (CMUSE) in a Patient with Down Syndrome: A Case Report
Reports — Medical Cases Images and Videos

Cryptogenic Multifocal Ulcerating Stenosing Enteritis (CMUSE) in a Patient with Down Syndrome: A Case Report

CMUSE can closely mimic Crohn's disease and may require surgery for diagnosis and symptom relief. Recognizing it can change diagnostic pathways and multidisciplinary management for people with recurrent small-bowel...

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The ‘Cross‐Trust’ Histopathology Multidisciplinary Team: Report of meeting outputs and impact on paediatric inflammatory bowel disease management in a UK tertiary centre
JPGN Reports

The ‘Cross‐Trust’ Histopathology Multidisciplinary Team: Report of meeting outputs and impact on paediatric inflammatory bowel disease management in a UK tertiary centre

A cross‑trust histopathology MDT helped reclassify diagnoses in a substantial proportion of discussed paediatric IBD cases and occasionally changed management or transition planning, which could affect treatment...

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Meta-analysis: safety and efficacy of ustekinumab in pediatric inflammatory bowel disease patients with anti-TNF failure.
BMC gastroenterology

Meta-analysis: safety and efficacy of ustekinumab in pediatric inflammatory bowel disease patients with anti-TNF failure.

This review pools available pediatric data showing ustekinumab can induce and maintain remission after anti‑TNF failure, offering a treatment option for children with refractory IBD. Results are most robust for Crohn’s...

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Clinical characteristics and treatment patterns of older and younger patients with inflammatory bowel disease
World Journal of Gastroenterology

Clinical characteristics and treatment patterns of older and younger patients with inflammatory bowel disease

This study suggests that older-onset IBD is managed more conservatively and experiences fewer extraintestinal manifestations. Patients and clinicians should be aware that age can influence treatment choices and that...

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Ulcerative colitis with a mutation in the HMBS gene associated with acute intermittent porphyria
Experimental and Clinical Gastroenterology

Ulcerative colitis with a mutation in the HMBS gene associated with acute intermittent porphyria

Finding a pathogenic HMBS variant in a child with extensive ulcerative colitis suggests rare genetic conditions (like acute intermittent porphyria) can appear alongside or mimic IBD and might affect symptoms or...

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Comparative performance of intestinal ultrasound activity indices in pediatric ulcerative colitis: a prospective study.
Journal of Crohn's & colitis

Comparative performance of intestinal ultrasound activity indices in pediatric ulcerative colitis: a prospective study.

Noninvasive monitoring matters for children with UC because endoscopy is burdensome. If ultrasound (and simple measures like bowel wall thickness) can reliably detect moderate-to-severe disease, families may avoid some...

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