Condition
Broader IBD news covering Crohn's disease, ulcerative colitis, research, treatments, monitoring, and patient care.
Page 65 of 88 · 4187 articles
Perianal fistulas in Crohn's disease significantly affect quality of life, and this study provides an initially validated Spanish tool to measure that impact, enabling better assessment in Spanish-speaking patients and...
A natural compound (diosgenin) reduced disease signs and inflammatory markers in a mouse model of ulcerative colitis, suggesting a possible anti-inflammatory mechanism that could inform future preclinical research.
Children with IBD can have persistent gut–brain interaction symptoms even when inflammation is quiescent; these symptoms are linked with worse quality of life and higher anxiety. Recognizing DGBI-like symptoms may help...
Many people with IBD who achieve remission ask about reducing or stopping medication. This review summarises current evidence and highlights that withdrawal carries substantial relapse risk and that decisions should be...
Automated, sequence-robust MRI measures could help standardize detection and localization of perianal anoperineal lesions in Crohn’s disease, which is relevant for diagnosis and management of perianal complications.
Conversations about living with IBD and IBS can help people feel less isolated, learn practical coping strategies, and identify local support resources. Hearing from a specialist and from a caregiver can provide both...
A majority of surveyed IBD patients who use marijuana reported better quality of life and relief from symptoms such as nausea, joint pain, insomnia and anxiety — findings of interest to people seeking symptom management...
Based on the title and source metadata, this appears to be a video related to Crohn's disease, Inflammatory bowel disease, and Community and awareness. The original article is from cbsnews.com.
Based on the title and source metadata, this appears to be a patient education related to Crohn's disease, Inflammatory bowel disease, and Symptoms and flares. The original article is from msn.com.
The review examines whether removing the appendix could change the course of ulcerative colitis — a potential surgical option that might lower colectomy or hospitalization risk in some scenarios but also carries...
The article points to plant-derived compounds with anti-inflammatory and antioxidant actions that may be relevant to colitis mechanisms, which could be of interest to patients and clinicians following experimental or...
The study suggests Artemisia rupestris extract can reduce inflammation, repair the intestinal barrier, and shift the gut microbiota and metabolites in a mouse colitis model — pathways that are important in IBD. These...
For people with ulcerative colitis treated with infliximab for acute severe disease, whether to keep giving systemic corticosteroids afterward affects infection risk, steroid side effects, and disease control.
An LTE Phase 2 study offers longer-term safety monitoring and continued access to investigational long-acting antibody drugs for people who completed or met escape criteria in the parent SKYLINE-UC trial; that can matter...
This trial is testing a new experimental oral therapy (BRS201) aimed at reducing hydrogen sulfide–related metabolites in people with mild ulcerative colitis. If successful, the drug could represent a novel, non-biologic...
This trial tests etrasimod (an S1P receptor modulator) specifically in older adults with active ulcerative colitis — a group often underrepresented in IBD trials. Results could inform safety and short-term remission...
AIEC is linked to IBD pathogenesis but is defined by lab assays rather than clear genetic markers. This paper presents a practical assay to detect cell invasion even when isolates are resistant to gentamicin, which could...
Patients with Crohn's disease had a higher adjusted risk of periprosthetic joint infection within 90 days after elective joint replacement, while ulcerative colitis did not. This difference could affect preoperative risk...
The study investigates how components of exclusive enteral nutrition (EEN), particularly transforming growth factor‑β (TGF‑β), may help restore intestinal barrier function after colitis. That could help explain why EEN...
A treatable-traits approach could help tailor IBD care to each patient by targeting specific biological, comorbid, and psychosocial drivers of disease and quality-of-life impairment, potentially improving how we choose...
People with IBD may be interested because the review describes a probiotic (L. plantarum) and synbiotic approaches that could influence gut inflammation, barrier function, and microbiota—areas directly relevant to IBD...
Targeting STING may reduce inflammatory signaling that contributes to ulcerative colitis; a safer, more potent STING inhibitor could become a new therapeutic approach if later-stage studies confirm benefit and safety.
This research links molecular subtypes of ulcerative colitis to infliximab (anti-TNF) response using an interpretable machine-learning method, which could help identify which patients are more or less likely to respond...
Based on the title and source metadata, this appears to be a patient education related to Inflammatory bowel disease and Community and awareness. The original article is from pressreader.com.
AI could help identify dietary patterns, predict which patients might benefit from specific nutrition approaches, and provide personalized nutrition support — potentially improving inflammation and gut microbiome...
This research describes a new nanoparticle/hydrogel delivery system that reduced inflammation and helped restore the intestinal barrier in mouse models of ulcerative colitis. It suggests a potential future therapeutic...
This preclinical study reports a new pH-sensitive liposomal formulation that increased intestinal delivery and anti-inflammatory effects of roxadustat in animal models of colitis, which could be relevant to future oral...
This study identifies a specific probiotic–commensal interaction that improved colitis in mice and points to a metabolite (phosphatidylcholine) and metabolic pathway that might help repair the gut barrier — a pathway...
Oxidative stress may help explain some biological drivers of inflammation in Crohn’s disease and ulcerative colitis and could become a target for biomarkers or therapies in the future. Right now, the evidence is...
CMUSE can closely mimic Crohn's disease and may require surgery for diagnosis and symptom relief. Recognizing it can change diagnostic pathways and multidisciplinary management for people with recurrent small-bowel...
Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Chinese Journal of...
A cross‑trust histopathology MDT helped reclassify diagnoses in a substantial proportion of discussed paediatric IBD cases and occasionally changed management or transition planning, which could affect treatment...
Patients and clinicians often ask whether herbal formulas or plant compounds can help IBD. This preclinical study identifies quercetin and the PI3K–Akt pathway as potential mechanisms, which may guide future research...
The study suggests JAK and TYK2 inhibitors can directly change epithelial inflammatory signaling and proliferation in UC, which may be relevant to healing of the gut lining and how different drugs work beyond immune...
Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Tests and monitoring. The original article is from Cureus.
People with ulcerative colitis may be interested because synbiotic approaches aim to change the gut microbiome and intestinal barrier and therefore could become a future therapeutic option or adjunct. The paper...
People with UC who need biologic therapy during conception or pregnancy often face limited evidence about safety and effectiveness; this case suggests ustekinumab may be an option when other drugs fail or are stopped for...
The paper describes a potential new anti-inflammatory/hepatoprotective candidate (a cyanobacterium extract) tested in mouse models of liver injury and IBD — early-stage research that could guide future studies but is not...
The paper suggests that loss of microbial bile acid transformations in IBD reduces activation of the TGR5 receptor, and that lower TGR5 bioactivity correlates with higher inflammatory activity — a potential mechanism...
The study links tissue and blood molecular changes to UC severity, suggesting candidate mechanisms (fibrogenesis, neutrophil activation) that could lead to biomarkers or new therapeutic targets. Understanding severity...
The study identifies a plant-derived compound that reduced inflammation and liver injury in a mouse model of ulcerative colitis and ties its effects to both JAK2/STAT1 inhibition and changes in the gut microbiota—two...
Fecal calprotectin measured by a point‑of‑care CGICA assay showed high accuracy for identifying colorectal inflammation and IBD in patients with chronic diarrhea, which could help avoid some unnecessary colonoscopies...
This review pools available pediatric data showing ustekinumab can induce and maintain remission after anti‑TNF failure, offering a treatment option for children with refractory IBD. Results are most robust for Crohn’s...
An updated drug label for AMJEVITA affects people with Crohn's disease, ulcerative colitis, and other immune conditions because it defines FDA‑approved uses, dosing schedules (including pediatric dosing), and safety...
Based on the title and source metadata, this appears to be a clinical study related to Inflammatory bowel disease and Research and clinical trials. The original article is from hmpgloballearningnetwork.com.
Earlier use of advanced therapies and less steroid exposure could affect long-term outcomes and side-effect risk for people with newly diagnosed IBD. The study also identifies lower use of advanced therapies among...
If the appendix is a significant source of harmful IgG antibodies in ulcerative colitis, that could help explain why appendectomy sometimes reduces UC risk or severity and might influence future therapies targeting...
This study suggests that older-onset IBD is managed more conservatively and experiences fewer extraintestinal manifestations. Patients and clinicians should be aware that age can influence treatment choices and that...
