Condition
Broader IBD news covering Crohn's disease, ulcerative colitis, research, treatments, monitoring, and patient care.
Page 66 of 88 · 4183 articles
Non-invasive biomarkers that reflect mucosal inflammation and systemic disease activity could help reduce reliance on frequent endoscopy and guide monitoring for people with Crohn’s disease or ulcerative colitis.
Chronic pain affects many people with IBD even after inflammation is controlled, often limiting daily activities and worsening mental health. Understanding that pain can persist without active inflammation highlights the...
If you have IBD, J&J’s ICOTYDE/TREMFYA‑class program could expand oral IL‑23 treatment options for ulcerative colitis and Crohn’s disease and may have implications for perianal fistulizing Crohn’s disease — an area with...
Patients facing total proctocolectomy may care because the surgical approach can affect the chance of needing to convert to open surgery, how long the operation takes, and the short-term risk of complications like...
Probiotics like Lactobacillus GG are often considered by families of children with Crohn’s disease. If helpful, they could offer a low-risk adjunct that targets the gut microbiome and barrier function. This pilot study...
The study describes a new oral nanotherapy that delivered apremilast to the inflamed colon in mice and reportedly reduced gut inflammation and behaviors resembling anxiety/depression—suggesting a combined...
The study describes a new oral, colon‑targeted delivery system that improved outcomes in a mouse model of ulcerative colitis and shifted immune and microbiome markers—research that could inform future therapies focused...
This trial tests an oral integrin α4β7 inhibitor for Crohn’s disease, a new small-molecule approach aiming to block gut-specific immune cell trafficking similar to existing biologic anti‑integrin drugs. If effective and...
Combining a UC biologic (mirikizumab) with a weight-loss drug (tirzepatide) could address both intestinal inflammation and excess weight, which may be important for people with moderately to severely active ulcerative...
People with Crohn’s disease often have disrupted gut microbiomes; this trial tests a food-based approach (cranberry powder) that could potentially encourage beneficial bacteria and reduce inflammation, which is of direct...
This trial tests two investigational agents (eltrekibart and mirikizumab) for moderate–severe ulcerative colitis, which may offer additional treatment options if proven safe and effective. It’s relevant to people whose...
AI could help make assessments (endoscopy, histology, imaging) more objective and combine complex data to better predict disease course—potentially improving personalized care planning for people with IBD.
This study suggests a specific probiotic strain may help reduce colitis in mice by changing the gut microbiome and boosting host phosphatidylcholine production — a pathway that could be relevant to gut barrier repair in...
A new patient-derived “Colon Chip” reproduces key features of Crohn’s disease and ulcerative colitis in the lab and points to fibroblasts as active drivers of inflammation and early cancer-associated changes — insights...
Based on the title and source metadata, this appears to be a clinical study related to Inflammatory bowel disease and Medications. The original article is from Cureus.
Knowing the makeup and regional distribution of IBD specialists helps identify gaps in care access and guide training or policy efforts to expand specialist capacity in underserved areas.
Researchers exploring new anti-inflammatory or antioxidant compounds for ulcerative colitis may find sanggenol L’s effects on Nrf2/HO-1 and TLR4/p65 signalling of interest. Patients should note this is early-stage,...
FMT and precision microbiota therapies target the gut ecosystem, a modifiable factor in UC. For people with UC, this review explains potential mechanisms, where FMT has shown benefit in trials, and why it is still...
Blood markers that correlate with endoscopic healing could help track inflammation noninvasively and may reduce the frequency of endoscopy if validated. For people with IBD, better blood-based tools could make monitoring...
Cure8 found this source from Journal of gastroenterology and hepatology, but the page could not be read reliably yet. It is tagged for Inflammatory bowel disease and Diet and lifestyle. Open the original article for the...
Cure8 could only read part of this source from theaustralian.com.au, so this card uses cautious topic tags instead of a full summary. It is tagged for Crohn's disease, Inflammatory bowel disease, and Access, cost, and...
Pouchitis affects a large share of patients after IPAA surgery and causes significant morbidity. Identifying pre-surgery immune, epithelial, or microbial signatures that predict pouchitis could help guide who should get...
A validated human peristaltic intestinal organoid model could make preclinical testing more predictive for drugs affecting gut motility and reduce reliance on animal models.
People with IBD often receive general advice to eat more fiber, but certain purified fibers or fiber-enriched foods may help some people while worsening inflammation in others. Research that teases apart fiber types and...
People with HαT report GI symptoms often labeled IBS; this study aims to test whether intestinal barrier dysfunction and specific food proteins trigger mucosal and mast-cell responses that could explain symptoms. If...
Tertiary lymphoid organs form in IBD and may influence disease course; understanding how lymphatic S1PR1 controls TLOs could reveal new targets to modify intestinal inflammation without broad immunosuppression.
Understanding gene–microbe interactions that drive site-specific disease in very early-onset Crohn’s could reveal why some children develop ileal versus colonic disease and suggest new approaches to prevention or...
Perioperative nutrition could affect recovery after Crohn’s bowel surgery; a trial of Exclusive Enteral Nutrition may show whether a pre- or peri-surgical liquid diet reduces complications and improves outcomes. Patients...
Pyoderma gangrenosum is an uncommon but important extraintestinal skin complication that can occur with ulcerative colitis and may be mistaken for infection. Recognizing it matters because treatment and wound care differ...
Finding a pathogenic HMBS variant in a child with extensive ulcerative colitis suggests rare genetic conditions (like acute intermittent porphyria) can appear alongside or mimic IBD and might affect symptoms or...
People with IBD who undergo liver transplantation — especially those with PSC — can have different UC course and treatment needs because transplant immunosuppression and the liver disease itself affect the bowel.
Granulomas are a classic histologic feature of Crohn’s disease, so patients and clinicians may wonder whether their presence predicts worse disease or different treatment needs. This review shows existing studies are...
This study highlights factors—tumor location, age, smoking, and having IBD—that were associated with survival and progression in a Lebanese CRC cohort.
Adherent-invasive E. coli (AIEC) is implicated in Crohn’s disease inflammation in some patients. This review maps possible ways to target AIEC specifically, which could lead to therapies that reduce infection-driven...
The study identifies a gut bacteria–liver signaling axis (Lactobacillus johnsonii → hepatic LXRα–SCD1) that may explain how altered hepatic lipids contribute to UC and related liver injury, and shows pristimerin can...
Changes to aeromedical waiver policy could allow some aviators with well-controlled Crohn’s disease to remain or return to flight duty, affecting careers and military readiness while aiming to preserve safety.
Fecal calprotectin is a noninvasive stool biomarker used to detect intestinal inflammation and to help distinguish IBD from noninflammatory conditions.
Based on the title and source metadata, this appears to be a patient education related to Crohn's disease, Inflammatory bowel disease, and Flare. The original article is from msn.com.
Extraintestinal manifestations are common in IBD and — according to this study — linked to significantly worse quality of life across social, systemic, intestinal, and emotional domains. Recognizing and treating EIMs may...
Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and CRP. The original article is from Alimentary Pharmacology & Therapeutics.
The study examines whether recommended management for rectal inflammation in UC is followed in routine care and whether following guidelines affects 12-month remission — important for patients and clinicians aiming for...
Patients and clinics are still deciding how much care can be done remotely. Knowing who prefers in-person versus remote visits helps tailor care so patients receive the visit type they need and want, and supports...
Standard measures like BMI and routine labs can miss muscle and fat depletion in IBD patients. Better screening plus access to dietitian assessment could find treatable malnutrition that affects recovery and quality of...
The study identifies a food-derived compound that improved colitis in lab models and acted on JAK/STAT3 signaling and intestinal barrier proteins—pathways relevant to IBD inflammation and mucosal healing.
Biomaterials that directly modify immune responses could offer new localized, targeted ways to treat gut inflammation, potentially reducing reliance on systemic immunosuppressive drugs. This review summarizes preclinical...
Sexual dysfunction is common in IBD and—according to this study—appears more strongly linked to psychological and demographic factors than to disease activity or muscle loss. Recognizing and treating mental-health issues...
The study describes a new urine-based fluorescent biosensor that detected inflamed intestinal sites and tracked treatment response earlier and more sensitively than fecal calprotectin in a mouse model of IBD, which could...
Self‑management programs delivered by nurses may help people with IBD improve daily functioning, confidence in managing their condition, and quality of life even when inflammation markers don’t change. That matters...
