Complications

A drug (flucytosine) caused colitis that looked like an ulcerative colitis flare. Mistaking medication-induced colitis for IBD activity could lead to unnecessary changes in immunosuppressive treatment.

Genetic evidence for causal links between other diseases (for example asthma or multiple sclerosis) and IBD can help researchers prioritize biological pathways and potential therapeutic targets, and may explain why some...

Because PG is linked to IBD and can be triggered by surgery, a perioperative immunosuppressive approach reported here may be relevant to patients with IBD who have had prior PG or are planning reconstructive surgery.

Pathological features of intestinal lesions help doctors and researchers understand disease progression, identify complications, and interpret biopsies. Improvements or corrections to such descriptions can affect how...

The study suggests that a simple, multidomain functional measure (intrinsic capacity) is linked to later IBD risk and that combining it with genetic risk may better identify people at higher risk—especially for Crohn’s...

This preclinical study suggests a heat‑killed form of Lactobacillus acidophilus LA‑5 reduced inflammation, oxidative stress, and markers of regulated cell death in a mouse model of ulcerative colitis — with effects...

For people with multi-refractory Crohn’s disease or ulcerative colitis, adding a JAK inhibitor to an existing biologic (advanced combination therapy) may convert partial responses into deeper remission in selected cases,...

Psoriasis and Crohn’s disease share immune pathways that affect treatment choices. Some biologics work across both conditions while others (notably IL-17 inhibitors) may be inappropriate for patients with active IBD.

Based on the title and source metadata, this appears to be a systematic review or meta analysis related to Inflammatory bowel disease and Complications. The original article is from Cureus.

The study shows malnutrition is common in Crohn’s disease and much more likely during active inflammation, highlighting the need for routine nutritional screening and more than one type of assessment.

The study links a common dietary fiber (green banana resistant starch) to microbiota changes and production of propionate that protect the colonic barrier and reduce inflammation in a mouse model of ulcerative colitis.

A new IL-17A drug (vunakizumab) is reported to have triggered severe ulcerative colitis in one patient, suggesting clinicians and patients starting IL-17A inhibitors should watch for early gastrointestinal symptoms.

This real-world multicenter study provides short-term effectiveness and safety data for upadacitinib in a difficult-to-treat Crohn’s population in China, which may inform treatment decisions and risk discussions.

People with IBD already have a higher baseline risk of colorectal cancer. This study finds that having multiple first‑degree relatives with CRC adds the largest absolute additional risk, which could affect how...

The study identifies Piezo1 in intestinal epithelial cells as a potential driver of intestinal fibrosis in IBD via a stiffness → ROS → partial EMT pathway, and suggests targeting Piezo1 or ROS could reduce fibrosis in...

If you or a child had Kawasaki disease, this study suggests there may be a higher long-term chance of certain skin autoimmune conditions (psoriasis, vitiligo) but no clear increase in IBD or several other autoimmune...

Malnutrition was common and much more frequent during active Crohn’s disease in this South Asian cohort, which matters because poor nutritional status affects treatment tolerance, recovery, and quality of life.

The study highlights a bacterial gene that helps adherent-invasive E. coli (AIEC) colonize the gut — a mechanism that has been linked to Crohn's disease. Understanding how AIEC colonizes could guide future research into...

People with IBD are at higher risk for colorectal cancer; identifying stromal genes that track inflammation-driven EMT could help researchers find biomarkers or targets that explain how chronic inflammation promotes...

A blood test (serum REG3α) may help identify people at higher risk of developing complicated Crohn's disease years before diagnosis and predict progression in established disease, which could inform monitoring or early...

Patients with UC and their clinicians may encounter CMV on colon biopsy testing; this study suggests CMV detection is linked with higher mucosal inflammation and a less favorable long-term course, highlighting a...

This FDA drug-label update describes approved uses and safety warnings for tofacitinib, a JAK inhibitor used in immune-mediated diseases including ulcerative colitis. The boxed warnings highlight serious infection and...

Sarcopenia (loss of muscle mass/strength) was common among hospitalized adults with active UC and linked to inflammation, changes in blood metabolites (bile acids, acylcarnitines), and shifts in the gut microbiome.

The work links a PD risk gene (LRRK2 G2019S) to increased intestinal NET formation and enteric α-synuclein in mouse colitis, suggesting a neutrophil-mediated inflammatory route by which gut inflammation and microbiota...

If AJs and E-cadherin signaling influence intestinal inflammation, that could change how researchers think about IBD causes and point to new molecular targets for study.

The study links a common environmental chemical (BPA) to worse epithelial injury and inflammation in colitis models, highlighting a potential environmental contributor to IBD-relevant epithelial dysfunction and...

PSC — a serious bile-duct disease linked to IBD — was found on MRCP in about 1 in 10 people at IBD diagnosis, often without abnormal liver blood tests. Early radiological detection could affect monitoring and specialist...

This is the official FDA label text for dexamethasone, so it clarifies approved uses and gives practical dosing and tapering guidance. It explicitly names "regional enteritis and ulcerative colitis," which matters to...

Herpes zoster is more common and can be more severe in people with IBD, especially those on certain immunosuppressive drugs. Understanding therapy-specific risks and vaccine options can help prevent painful...

This report highlights that Langerhans cell histiocytosis can present with intestinal ulcerations mimicking IBD and may be missed if standard IBD treatments don’t help. Patients with persistent bleeding or nonresponsive...

Cure8 could only read part of this source from dermatologytimes.com, so this card uses cautious topic tags instead of a full summary. It is tagged for Crohn's disease and Complications.

Iliopsoas abscess is an uncommon but serious penetrating complication of Crohn’s disease that can present with non-specific symptoms and be missed. The review compiles case-level evidence about presentation, diagnosis,...

If confirmed, a simple calprotectin test on fistula scrapings could help predict which Crohn’s patients are likely to heal after primary surgical fistula closure and which may need additional therapies, potentially...

Identifies mast-cell–derived IL-13 as a likely contributor to intestinal fibrosis in Crohn disease, a complication not reliably prevented by current anti-inflammatory treatments. The finding points to a specific immune...

Ileal pouch disorders are common after IPAA surgery and cause symptoms many patients will experience. Early recognition and initial treatment by primary care can speed symptom relief and identify patients who need...

Based on the title and source metadata, this appears to be an opinion or commentary related to Crohn's disease, Inflammatory bowel disease, and Complications. The original article is from Reumatologia.

Label changes for RENFLEXIS affect people with Crohn's disease or ulcerative colitis who take (or may be prescribed) infliximab biosimilars — the label includes dosing, age indications, and important safety warnings that...

If you have IBD, emerging forms of regulated cell death may help explain ongoing intestinal inflammation and could become targets for future tests or treatments. This review highlights multiple RCD pathways linked to...

This preclinical study suggests that a specific gut microbe (Bacteroides acidifaciens) and the bile acid UDCA can reduce inflammation in a mouse colitis model by improving barrier function and dampening NLRP3-driven...

Accurate recognition and standardized reporting of IBD-associated dysplasia help guide surveillance and surgical decisions because some dysplastic variants are flat, endoscopically invisible, and linked to advanced or...

Anaemia is a common and impactful complication in children diagnosed with IBD; knowing how often it occurs, which subtypes are most frequent, and its link with disease activity can guide monitoring and management...

Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from International...

The study suggests a common environmental pollutant could worsen intestinal inflammation in experimental colitis and identifies molecular pathways that might mediate that effect, which could be relevant to understanding...

The findings suggest blood DNA methylation changes may mark UC long before symptoms start; that could eventually enable earlier risk identification or research into preventing progression to symptomatic disease.

People with diabetes and fatty liver disease may eventually benefit from new adjunctive therapies that target liver inflammation, fibrosis, and oxidative stress; this study reports promising preclinical signals for a...

Surgery is common in Crohn’s disease and timing may relate to disease severity and long-term outcomes. Understanding factors linked to early surgery helps patients and clinicians weigh risks and expectations after...

DOTATATE PET/CT can show uptake in non‑neuroendocrine diseases, which may lead to misdiagnosis or unnecessary treatments if imaging findings are not confirmed. People with Crohn's disease or other abdominal pathology who...

Thiopurines are commonly used in IBD (azathioprine, 6-mercaptopurine). This review links these drugs — especially 6-thioguanine — to liver microvascular injury that can lead to portal hypertension, which may present...