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Mental health and quality of life

Anxiety, depression, fatigue impact, adherence, social life, and quality-of-life news.

Page 2 of 6 · 246 articles

Temporal trends in depression-related hospitalizations and suicide among patients with inflammatory bowel disease.
Journal of the Canadian Association of Gastroenterology

Temporal trends in depression-related hospitalizations and suicide among patients with inflammatory bowel disease.

Depression and suicide are important concerns for people with IBD. This study shows higher hospitalization risk for depression in IBD but a decline in those hospitalizations over time, which may reflect changing care...

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Exploring endoscopy sedation experiences in young adults with pediatric-onset inflammatory bowel disease after transfer to adult gastroenterology care.
Journal of the Canadian Association of Gastroenterology

Exploring endoscopy sedation experiences in young adults with pediatric-onset inflammatory bowel disease after transfer to adult gastroenterology care.

Endoscopy comfort and sedation differ between pediatric and adult settings, and worse adult experiences could deter young adults from needed surveillance or care. Addressing sedation choice, communication, and provider...

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Optimism and mindfulness are associated with decreased abdominal pain among adolescents with inflammatory bowel disease.
Journal of the Canadian Association of Gastroenterology

Optimism and mindfulness are associated with decreased abdominal pain among adolescents with inflammatory bowel disease.

Adolescents with IBD often experience abdominal pain that affects daily life. This study suggests psychological resilience — especially optimism and mindfulness — is linked with less pain, pointing to nonpharmacologic...

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IOIBD: the International Organization for the Study of Inflammatory Bowel Disease.
Therapeutic advances in gastroenterology

IOIBD: the International Organization for the Study of Inflammatory Bowel Disease.

IOIBD’s consensus frameworks and educational programs shape how IBD is studied and treated worldwide — affecting trial design, treatment goals, patient-reported outcome measures, and clinical guidance that patients and...

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Research hotspots, context, and future directions of ulcerative colitis comorbid with depression from 2006 to 2025: a bibliometric and visualization analysis
Frontiers in Medicine

Research hotspots, context, and future directions of ulcerative colitis comorbid with depression from 2006 to 2025: a bibliometric and visualization analysis

Depression is common in people with ulcerative colitis and affects quality of life and disease outcomes. Knowing research trends helps patients and clinicians see where evidence and care approaches are focused,...

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JAK1-preferential inhibition in refractory inflammatory bowel disease: reframing upadacitinib as a strategy for rapid immune recalibration.
Frontiers in immunology

JAK1-preferential inhibition in refractory inflammatory bowel disease: reframing upadacitinib as a strategy for rapid immune recalibration.

Upadacitinib is already used for some patients with UC and Crohn's; this article offers a structured way to think about why it can act quickly in refractory cases and what evidence would be needed to move from short‑term...

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Beyond mood: the neurobiological rationale for using SSRIs and SNRIs in the care of inflammatory bowel disease and disorders of gut-brain interaction.
Minerva gastroenterology

Beyond mood: the neurobiological rationale for using SSRIs and SNRIs in the care of inflammatory bowel disease and disorders of gut-brain interaction.

This review suggests SSRIs and SNRIs may influence both brain and gut pathways relevant to symptom burden in IBD and DGBI — potentially improving mood, pain, motility, and aspects of inflammation. That could matter for...

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Erythritol Exacerbates DSS-Induced Colitis and Influences Behavioral Responses in Mice Through Gut Microbiota and Metabolic Alterations
Microorganisms

Erythritol Exacerbates DSS-Induced Colitis and Influences Behavioral Responses in Mice Through Gut Microbiota and Metabolic Alterations

This study suggests erythritol — a common non-nutritive sweetener — may worsen experimental colitis and depression-like behavior in mice via microbiome and metabolic changes, raising questions about how ultra-processed...

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Natural History of Concomitant Immune-Mediated Inflammatory Diseases: Psoriatic Disease and Inflammatory Bowel Disease Regarding Disease Course and Healthcare Utilization – A JANL-HIP Study

People with PsD or IBD — or both — may develop the other condition years later, and the order of diagnoses appears linked to timing of the second disease and to differences in mortality for some groups. That could affect...

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To Clarify the Independent Role of Digital Learning and Nurse Support in the Self-Management of Inflammatory Bowel Disease
Digestive Diseases and Sciences

To Clarify the Independent Role of Digital Learning and Nurse Support in the Self-Management of Inflammatory Bowel Disease

Self-management support—whether through digital learning tools or nurse-delivered programs—can affect daily life for people with IBD. Understanding which element drives benefit could shape future care options and how...

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The Roles of Complementary Structured Exercise and Physical Therapy in The Aging and Older Adult IBD Patient Care Team.
Current treatment options in gastroenterology

The Roles of Complementary Structured Exercise and Physical Therapy in The Aging and Older Adult IBD Patient Care Team.

Older adults with IBD are at higher risk of functional decline; SE and PT are low-risk interventions that may help reduce frailty, sarcopenia, fatigue, joint pain, and improve postoperative recovery and quality of life.

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Disability among Palestinian patients with inflammatory bowel disease: evaluation using the IBD Disk and identification of associated factors.
Crohn's & colitis 360

Disability among Palestinian patients with inflammatory bowel disease: evaluation using the IBD Disk and identification of associated factors.

Disability related to IBD affects daily functioning and quality of life; identifying factors linked with higher or lower disability (vitamin D status, azathioprine use, smoking) can help patients and clinicians consider...

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Psychosocial Experience, Impacts and Management of Fatigue in Young People With Inflammatory Bowel Disease—A Systematic Review
JCC Plus

Psychosocial Experience, Impacts and Management of Fatigue in Young People With Inflammatory Bowel Disease—A Systematic Review

Fatigue is a common, impactful symptom in pediatric and young-adult IBD but is poorly defined and measured, limiting the ability to design age-appropriate supports. This review highlights gaps that affect patients' daily...

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Retinal microvascular alterations detected by optical coherence tomography angiography in patients with inflammatory bowel disease.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

Retinal microvascular alterations detected by optical coherence tomography angiography in patients with inflammatory bowel disease.

IBD may involve small-vessel changes beyond the gut. If reproducible, retinal microvascular alterations detectable by OCTA could offer a non-invasive window into systemic microvascular involvement in IBD.

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Remote monitoring to improve engagement for patients with inflammatory bowel disease: a randomized clinical trial.
Crohn's & colitis 360

Remote monitoring to improve engagement for patients with inflammatory bowel disease: a randomized clinical trial.

Remote text monitoring is appealing as a low-cost way to support people with IBD on biologics, but this trial suggests it may not boost quality of life or adherence over 4 months when adherence is already high. Patients...

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Health-Related quality of life in Russian children with inflammatory bowel disease is comparable across disease types and treatment modalities
Frontiers in Pediatrics

Health-Related quality of life in Russian children with inflammatory bowel disease is comparable across disease types and treatment modalities

The paper suggests that HRQoL and family functioning may be similar across disease types and common treatment approaches in children with IBD, but emotional health and parental worry remain areas needing attention.

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Exercise-based and mind-body movement interventions for depressive symptoms in patients with inflammatory bowel disease: a systematic review and meta-analysis of randomized controlled trials
Frontiers in Psychiatry

Exercise-based and mind-body movement interventions for depressive symptoms in patients with inflammatory bowel disease: a systematic review and meta-analysis of randomized controlled trials

Depressive symptoms are common in IBD and can worsen quality of life and disease management; non-drug options that may improve mood are especially relevant for patients seeking adjunctive or accessible therapies.

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Latent profile analysis of fertility motivation in women with inflammatory bowel disease: a cross-sectional study
BMC Women s Health

Latent profile analysis of fertility motivation in women with inflammatory bowel disease: a cross-sectional study

Decisions about having children are common and sometimes complex for women living with IBD. This study maps different motivation patterns and the factors linked to them, which could help clinicians tailor reproductive...

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Associations between multidimensional sleep health and inflammatory bowel disease onset and activity: A systematic review of the RU-SATED framework
World Journal of Psychiatry

Associations between multidimensional sleep health and inflammatory bowel disease onset and activity: A systematic review of the RU-SATED framework

Sleep disturbance is common in IBD and may relate to disease risk and flares. Understanding which sleep problems are linked to onset or activity could point to new ways to support people with IBD.

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The Impact of Fistulizing Disease, Treatment Modalities, and Clinical Activity on Health-Related Quality of Life in Crohn's Disease.
Digestive diseases and sciences

The Impact of Fistulizing Disease, Treatment Modalities, and Clinical Activity on Health-Related Quality of Life in Crohn's Disease.

The study indicates that active inflammation—measured by CDAI and PDAI—drives poorer quality of life in Crohn's disease more than the mere presence of fistulas. That shifts focus toward controlling inflammation to...

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Ziwu-Liuzhu-guided combined external therapy promotes wound healing in postoperative perianal fistulizing Crohn’s disease
World Journal of Gastrointestinal Surgery

Ziwu-Liuzhu-guided combined external therapy promotes wound healing in postoperative perianal fistulizing Crohn’s disease

Perianal fistulizing Crohn’s disease causes delayed healing and high recurrence after surgery. This study suggests a specific time-guided external traditional therapy may speed wound healing, reduce inflammation, and...

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ĐẶC ĐIỂM RỐI LOẠN TRẦM CẢM Ở NGƯỜI BỆNH CROHN ĐIỀU TRỊ TẠI TRUNG TÂM TIÊU HÓA- GAN MẬT BỆNH VIỆN BẠCH MAI
Tạp chí Y học Cộng đồng

ĐẶC ĐIỂM RỐI LOẠN TRẦM CẢM Ở NGƯỜI BỆNH CROHN ĐIỀU TRỊ TẠI TRUNG TÂM TIÊU HÓA- GAN MẬT BỆNH VIỆN BẠCH MAI

Depression is common in people with Crohn’s disease and can affect quality of life and ability to manage IBD. Knowing prevalence and common symptoms locally helps clinicians and patients recognize and seek appropriate...

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Exploratory Risk Patterns of Steroid Dependency in Ulcerative Colitis: A Multicenter Pilot Study Combining Logistic Regression and Self-Organizing Map Analysis.
Inflammatory intestinal diseases

Exploratory Risk Patterns of Steroid Dependency in Ulcerative Colitis: A Multicenter Pilot Study Combining Logistic Regression and Self-Organizing Map Analysis.

Steroid dependency affects many people with ulcerative colitis and can change long-term treatment plans. This study explores clinical factors and uses an AI clustering method to visualize different risk patterns, which...

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A joint transdisciplinary approach for paediatric inflammatory bowel disease: Integrating nursing, dietetic and psychological support.
JPGN reports

A joint transdisciplinary approach for paediatric inflammatory bowel disease: Integrating nursing, dietetic and psychological support.

Integrated joint appointments could make it easier for children with IBD and their families to get coordinated care for symptoms, nutrition, and mental health in a single visit, which may improve access and reduce stigma...

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The chain mediating roles of stigma and health-promoting lifestyle in the relationship between disability index and posttraumatic growth among patients with inflammatory bowel disease.
Frontiers in public health

The chain mediating roles of stigma and health-promoting lifestyle in the relationship between disability index and posttraumatic growth among patients with inflammatory bowel disease.

PTG and psychological wellbeing matter to many people with IBD. This study indicates that addressing stigma and promoting healthy lifestyle behaviours could be linked with better psychological outcomes, making these...

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Persistent disease burden despite advanced therapies in inflammatory bowel disease: a real-world patient-reported survey from Greece.
Frontiers in immunology

Persistent disease burden despite advanced therapies in inflammatory bowel disease: a real-world patient-reported survey from Greece.

Many people with IBD still experience active disease, poor quality of life, work impairment, and depression even while on advanced therapies — highlighting gaps in how we measure and manage treatment success. Who this...

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Data-driven subphenotyping uncovers ulcerative colitis subtype with high risk for relapse in Japan: a prospective multicenter cohort study
The Lancet Regional Health - Western Pacific

Data-driven subphenotyping uncovers ulcerative colitis subtype with high risk for relapse in Japan: a prospective multicenter cohort study

The study suggests quality-of-life and patient-reported measures can reveal a subgroup of UC patients in clinical remission who nevertheless have higher relapse risk, which could help personalize monitoring and care.

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Comorbidity Between Mood Disorders and Chronic Somatic Diseases, With a Focus on Cardiometabolic Disease, and Its Mechanistic Crosstalk.
Depression and anxiety

Comorbidity Between Mood Disorders and Chronic Somatic Diseases, With a Focus on Cardiometabolic Disease, and Its Mechanistic Crosstalk.

Mood disorders commonly co-occur with chronic somatic diseases, including IBD; understanding shared mechanisms may explain worse outcomes and suggest multidisciplinary care needs.

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An Overview of the Rationale and Outcomes of Residential Camps for Children with Inflammatory Bowel Disease.
Pediatric gastroenterology, hepatology & nutrition

An Overview of the Rationale and Outcomes of Residential Camps for Children with Inflammatory Bowel Disease.

Children with IBD commonly experience emotional and social challenges; residential camps appear to improve quality of life, confidence, disease knowledge, and reduce isolation, making them relevant as a supportive,...

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Classifications of rheumatological extraintestinal manifestations in inflammatory bowel disease: Unmet needs in clinical practice and trials.
Inflammatory bowel diseases

Classifications of rheumatological extraintestinal manifestations in inflammatory bowel disease: Unmet needs in clinical practice and trials.

Rheumatological EIMs (notably joint inflammation) are frequent in IBD and affect quality of life; inconsistent definitions and lack of validated PROs make it harder for patients and clinicians to understand and compare...

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Developing a Self-Management Intervention to Improve Health Outcomes for Patients With Inflammatory Bowel Disease
ClinicalTrials.gov

Developing a Self-Management Intervention to Improve Health Outcomes for Patients With Inflammatory Bowel Disease

Digital self-management programs could help people with active IBD build skills to manage symptoms and quality of life between clinic visits. This trial tests whether such a program is feasible, acceptable, and practical...

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Patient Preferences for Inflammatory Bowel Disease Treatment: Results from a Global Survey Conducted in Partnership with the European Federation of Crohn’s & Ulcerative Colitis Associations
The Patient - Patient-Centered Outcomes Research

Patient Preferences for Inflammatory Bowel Disease Treatment: Results from a Global Survey Conducted in Partnership with the European Federation of Crohn’s & Ulcerative Colitis Associations

This global survey shows that people with IBD prioritize symptom relief and psychological well-being over treatment features like administration route or speed of onset. That matters for shared decision-making, trial...

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