All topics

Mental health and quality of life

Anxiety, depression, fatigue impact, adherence, social life, and quality-of-life news.

Page 2 of 9 · 391 articles

Faecal urgency in Crohn's disease: associations with disease location and activity, psychobiological burden and adverse outcomes.
Revista espanola de enfermedades digestivas

Faecal urgency in Crohn's disease: associations with disease location and activity, psychobiological burden and adverse outcomes.

Faecal urgency is a frequent, disabling symptom in Crohn's disease that was common in this cohort and tied to poorer quality of life, mental-health burden, and more healthcare use over one year.

Read Summary
Psychological Functioning and Parent-Child Mental Health Interrelations in Pediatric Gastrointestinal Autoimmune Disorders.
Clinical child psychology and psychiatry

Psychological Functioning and Parent-Child Mental Health Interrelations in Pediatric Gastrointestinal Autoimmune Disorders.

Emotional functioning and parent-child mental health are linked with anxiety, depression, and quality of life in children with IBD and other GI autoimmune disorders. Identifying these issues may help families get...

Read Summary
Inflammatory comorbidity and quality-of-life burden in psoriasis with multiple biologic failure: a retrospective cohort study
Springer Science and Business Media LLC

Inflammatory comorbidity and quality-of-life burden in psoriasis with multiple biologic failure: a retrospective cohort study

Patients with multiple biologic failures appear more likely to have inflammatory comorbidities (including IBD) and to experience worse dermatology-related quality of life despite similar early skin improvement. That...

Read Summary
The influence of disease label, disease signs and levels of contact on the stigmatization of inflammatory bowel disease: A vignette experiment.
Social science & medicine (1982)

The influence of disease label, disease signs and levels of contact on the stigmatization of inflammatory bowel disease: A vignette experiment.

Stigma and avoidance can harm social and work functioning for people with IBD. Knowing which factors increase avoidance (visible symptoms, prolonged contact, absence of a diagnosis label) can help patients and clinicians...

Read Summary
Treatment burden, adaptation, and support needs during exclusive enteral nutrition in children with Crohn's disease: a qualitative meta-synthesis.
Frontiers in nutrition

Treatment burden, adaptation, and support needs during exclusive enteral nutrition in children with Crohn's disease: a qualitative meta-synthesis.

EEN is a common treatment in paediatric Crohn's disease. Understanding the burdens and support needs can help families and clinicians plan practical, social, and school-based supports to improve adherence and experience...

Read Summary
Engineered E. coli Nissle 1917 alleviates colitis-associated depression via gut-brain axis restoration.
Science bulletin

Engineered E. coli Nissle 1917 alleviates colitis-associated depression via gut-brain axis restoration.

IBD patients often have depression and anxiety that current anti-TNF biologics do not adequately treat. An engineered probiotic that both neutralizes local TNFα and promotes GABA-producing microbes could address...

Read Summary
Experiences and Factors Influencing the Transition to Adult Care in Adolescents With Inflammatory Bowel Disease: A Mixed-Methods Systematic Review.
Journal of clinical nursing

Experiences and Factors Influencing the Transition to Adult Care in Adolescents With Inflammatory Bowel Disease: A Mixed-Methods Systematic Review.

Transition to adult care is a high-risk time when adolescents with IBD can experience care gaps and worsened disease control. Understanding which fixed and modifiable factors affect transition can help patients,...

Read Summary
Between-visit care represents a substantial and underrecognized component of health care utilization in pediatric inflammatory bowel disease
PubMed Central

Between-visit care represents a substantial and underrecognized component of health care utilization in pediatric inflammatory bowel disease

If you or your child has pediatric-onset IBD, much of the care that supports disease management happens between scheduled visits. Recognizing this workload matters for access, clinician time, and policies that affect...

Read Summary
Risk and characteristics of interstitial lung disease in patients with inflammatory bowel disease: A retrospective cohort study.
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG

Risk and characteristics of interstitial lung disease in patients with inflammatory bowel disease: A retrospective cohort study.

Interstitial lung disease (ILD) is an underrecognized extraintestinal complication in IBD that in this study was relatively common (12%) and associated with a substantially increased risk of death.

Read Summary
Peripartum mental illness in serial pregnancies in mothers with multiple sclerosis and other chronic diseases.
Multiple sclerosis (Houndmills, Basingstoke, England)

Peripartum mental illness in serial pregnancies in mothers with multiple sclerosis and other chronic diseases.

Mothers with chronic diseases such as MS and IBD appear to have higher rates of peripartum mental illness requiring care across serial pregnancies, so awareness and monitoring during and between pregnancies may be...

Read Summary
Health Related Quality of Life in Patients with Inflammatory Bowel Disease in Department of Gastroenterology of Dhaka Medical College Hospital: An Observational Study.
Mymensingh medical journal : MMJ

Health Related Quality of Life in Patients with Inflammatory Bowel Disease in Department of Gastroenterology of Dhaka Medical College Hospital: An Observational Study.

Quality of life is often substantially affected in IBD; this study identifies active disease, greater severity, prior surgery, and stricturing Crohn's disease as factors linked to lower HRQoL, highlighting areas...

Read Summary
Burden of Mental Disorders and Related Factors in Pediatric Patients with Ulcerative Colitis in Korea
Journal of Pharmacoepidemiology and Risk Management

Burden of Mental Disorders and Related Factors in Pediatric Patients with Ulcerative Colitis in Korea

This paper suggests children and teens with ulcerative colitis have higher rates of diagnosed mental disorders and antidepressant use compared with peers, indicating mental-health needs are an important part of pediatric...

Read Summary
AI-generated guidance for non-specialist physicians managing inflammatory bowel disease: expert evaluation and case-based testing of GPT-4 and DeepSeek.
Digestion

AI-generated guidance for non-specialist physicians managing inflammatory bowel disease: expert evaluation and case-based testing of GPT-4 and DeepSeek.

Non-specialist physicians often manage IBD where specialists are scarce. If reliable, AI tools could improve non-specialists' clinical reasoning and decision-making for IBD care.

Read Summary
Influencing factors of health-related productivity loss among patients with inflammatory bowel disease in paid employment based on the theory of social ecosystem: a mixed-methods study.
Minerva gastroenterology

Influencing factors of health-related productivity loss among patients with inflammatory bowel disease in paid employment based on the theory of social ecosystem: a mixed-methods study.

Work-related productivity loss was common in this study and linked to both clinical (disease activity, strictures, fatigue) and psychosocial factors (anxiety, depression, self-efficacy, social support).

Read Summary
Evaluation of a Mental Health Care App-Based Fatigue Management Program for Patients With Inflammatory Bowel Disease in Remission: Protocol for a Randomized Controlled Trial.
JMIR research protocols

Evaluation of a Mental Health Care App-Based Fatigue Management Program for Patients With Inflammatory Bowel Disease in Remission: Protocol for a Randomized Controlled Trial.

Fatigue greatly affects quality of life for people with IBD even in remission; if effective and scalable, a mobile CBT program could offer accessible symptom support. The trial will also examine engagement factors...

Read Summary
A Comprehensive Self-Management Intervention for Individuals With Inflammatory Bowel Disease
ClinicalTrials.gov

A Comprehensive Self-Management Intervention for Individuals With Inflammatory Bowel Disease

Self-management programs that teach cognitive behavioral strategies, symptom tracking, relaxation, sleep and diet skills could help people with IBD manage symptoms and day-to-day quality of life without relying solely on...

Read Summary
The role of metabolic crosstalk between Intestinal epithelial cells and immune cells in inflammatory bowel disease and targeting strategies
Frontiers in Immunology

The role of metabolic crosstalk between Intestinal epithelial cells and immune cells in inflammatory bowel disease and targeting strategies

Metabolic interactions between epithelial and immune cells may help explain persistent inflammation and barrier problems in IBD and point to new therapeutic targets that could complement current immune-targeting drugs.

Read Summary
Beyond inflammation control: Rethinking fatigue as a multidimensional target in Crohn’s disease management
World Journal of Gastroenterology

Beyond inflammation control: Rethinking fatigue as a multidimensional target in Crohn’s disease management

Fatigue markedly affects quality of life for people with Crohn’s and often remains after inflammation is controlled. Recognizing multiple drivers — psychological distress and immune/hematologic signals — could change how...

Read Summary
Managing IBS-Like Symptoms in Quiescent Inflammatory Bowel Disease: A Meta-Analysis of Randomized Trials.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Managing IBS-Like Symptoms in Quiescent Inflammatory Bowel Disease: A Meta-Analysis of Randomized Trials.

People with IBD in remission commonly continue to have IBS-like symptoms; this review summarizes randomized trial evidence for symptom-directed treatments and finds no definitive best option.

Read Summary
Biologics, small molecules, and extraintestinal malignancies in inflammatory bowel disease: practical questions and evidence-based answers.
Inflammatory bowel diseases

Biologics, small molecules, and extraintestinal malignancies in inflammatory bowel disease: practical questions and evidence-based answers.

People with IBD often need long-term advanced therapies. Cancer risk concerns commonly influence treatment choices—this review compiles current evidence to help patients and clinicians weigh risks when starting or...

Read Summary
KARAP Exacerbates Intestinal Inflammation Through Promoting Kyn-AhR-dependent Neutrophil Activation in Ulcerative Colitis.
Cellular and molecular gastroenterology and hepatology

KARAP Exacerbates Intestinal Inflammation Through Promoting Kyn-AhR-dependent Neutrophil Activation in Ulcerative Colitis.

The paper identifies a neutrophil-related immune pathway (KARAP → IDO1–kynurenine → AhR → IL-22) that contributes to mucosal inflammation in ulcerative colitis, suggesting a potential new target for research and drug...

Read Summary
Preexisting depression and early outcomes in inflammatory bowel disease: a propensity score-matched cohort study.
Proceedings (Baylor University. Medical Center)

Preexisting depression and early outcomes in inflammatory bowel disease: a propensity score-matched cohort study.

Depression before an IBD diagnosis was linked to more early treatment escalation and acute-care use after diagnosis. Recognizing preexisting depression could help clinicians identify patients who may benefit from closer...

Read Summary
High Prevalence of Fatigue is Linked to Depression in Inflammatory Bowel Disease.
Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates

High Prevalence of Fatigue is Linked to Depression in Inflammatory Bowel Disease.

Fatigue is extremely common in IBD and is closely linked to depression—recognizing and addressing mental-health issues may be important for patients who report significant fatigue.

Read Summary
Psychological Pathways From Disease Activity to Quality of Life in Ulcerative Colitis and Crohn's Disease: A Cross‐Sectional Serial Mediation Study
Journal of Clinical Nursing

Psychological Pathways From Disease Activity to Quality of Life in Ulcerative Colitis and Crohn's Disease: A Cross‐Sectional Serial Mediation Study

If disease activity hurts quality of life partly through low self-efficacy and (for UC) psychological distress, then boosting self-management confidence and identifying anxiety/depression could help improve...

Read Summary
Patient treatment engagement scale (PTES) for inflammatory bowel disease: exploring background factors.
BMC research notes

Patient treatment engagement scale (PTES) for inflammatory bowel disease: exploring background factors.

Patient engagement in treatment decisions can affect satisfaction, adherence, and care planning. This study identifies practical factors (treatment options, trusted providers, community support) associated with higher...

Read Summary
Retrospective analysis of ustekinumab in Crohn’s disease between biologic-naïve and biologic-experienced
Frontiers in Gastroenterology

Retrospective analysis of ustekinumab in Crohn’s disease between biologic-naïve and biologic-experienced

The study compares ustekinumab effectiveness between biologic‑naïve and biologic‑experienced Crohn’s patients and links clinical response to better quality of life and reduced anxiety — information relevant when...

Read Summary
Generational differences in illness perception among adults with inflammatory bowel disease: a multicenter cross-sectional study.
European journal of gastroenterology & hepatology

Generational differences in illness perception among adults with inflammatory bowel disease: a multicenter cross-sectional study.

How patients think about their IBD affects coping, treatment adherence, and quality of life. If different generations perceive illness threat and control differently, clinicians and care teams may need to tailor...

Read Summary
Using Pre-Study Patient Interviews to Refine Electronic Patient-Reported Outcomes in Clinical Research of Ustekinumab Induction for Ulcerative Colitis (SIRIUS Study)
Advances in Therapy

Using Pre-Study Patient Interviews to Refine Electronic Patient-Reported Outcomes in Clinical Research of Ustekinumab Induction for Ulcerative Colitis (SIRIUS Study)

Patient-informed refinements to ePRO design and study operations could reduce burden and missing data in high-frequency daily symptom reporting, which matters for study quality and for patients asked to report symptoms...

Read Summary
Results of the validated German Perceived Stress Questionnaire (PSQ) from a large German cohort of healthy adults and different disease groups compared to historical reference values
European Archives of Psychiatry and Clinical Neuroscience

Results of the validated German Perceived Stress Questionnaire (PSQ) from a large German cohort of healthy adults and different disease groups compared to historical reference values

Perceived stress affects quality of life and may influence symptom burden, disease management, and mental health in people with IBD. Updated PSQ benchmarks from a contemporary cohort help researchers and clinicians...

Read Summary
Oral manifestations of Crohn's disease: a clinical image highlighting the importance of interdisciplinary gastroenterological and dental care.
Polish archives of internal medicine

Oral manifestations of Crohn's disease: a clinical image highlighting the importance of interdisciplinary gastroenterological and dental care.

Based on the title and source metadata, this appears to be a patient education related to Crohn's disease, Inflammatory bowel disease, and Symptoms and flares. The original article is from Polish archives of internal...

Read Summary
Chất lượng cuộc sống và các yếu tố ảnh hưởng ở bệnh nhân viêm ruột mạn
Tạp chí Khoa học tiêu hóa Việt Nam

Chất lượng cuộc sống và các yếu tố ảnh hưởng ở bệnh nhân viêm ruột mạn

This study identifies modifiable lifestyle factors (meal regularity and spicy/sour food intake) linked to quality of life in people with IBD, which could inform practical counseling for patients.

Read Summary
Beyond the Bowel: A Narrative Review Examining Bidirectional Mental Health Pathways Across Disorders of Gut-Brain Interaction and Inflammatory Bowel Disease
Cureus

Beyond the Bowel: A Narrative Review Examining Bidirectional Mental Health Pathways Across Disorders of Gut-Brain Interaction and Inflammatory Bowel Disease

Based on the title and source metadata, this appears to be a systematic review or meta analysis related to Inflammatory bowel disease and Mental health and quality of life. The original article is from Cureus.

Read Summary
Deep learning-based assessment of ulcerative colitis activity from full-length endoscopic videos with spatial characterisation and histological correlation
medRxiv

Deep learning-based assessment of ulcerative colitis activity from full-length endoscopic videos with spatial characterisation and histological correlation

Automated analysis of full-length endoscopy videos could standardise assessment of UC activity, identify spatial patterns of inflammation, and better estimate histological healing—information that may influence treatment...

Read Summary
Financial Hardship Among US Adults with Inflammatory Bowel Disease: A National Analysis.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract

Financial Hardship Among US Adults with Inflammatory Bowel Disease: A National Analysis.

Financial barriers are common among US adults with IBD and are linked to delayed care and skipping medications — problems that can worsen disease control and quality of life.

Read Summary