Patient groups
Articles focused on children and teens with Crohn's disease or IBD, including pediatric research, care, and family context.
Page 2 of 6 · 252 articles
The trial suggests starting infliximab early can delay the need for further biologic escalation in children with moderate-to-severe Crohn’s disease, and that stopping anti‑TNF after induction often leads to relapse.
Understanding how individual diet and microbiome patterns relate to disease activity could help create personalized dietary approaches for children with Crohn's disease and improve monitoring using home fecal...
Cure8 could only read part of this source from American Journal of Therapeutics, so this card uses cautious topic tags instead of a full summary. It is tagged for Ulcerative colitis, Infliximab, and Ustekinumab.
A dedicated Digestive Health Centre could make it easier for people with IBD (including children and teens) to access coordinated care—fewer separate visits and more centralized specialist services in one location.
A Meckel diverticulum can present like Crohn’s disease and may be the true cause when IBD treatment fails; identifying it can lead to a surgical cure for symptoms such as anemia and obstruction.
Abnormal liver tests are common in children with IBD and can come from many causes, including the disease itself or the medicines used to treat it. A practical approach helps avoid stopping effective IBD therapy...
Malnutrition and impaired growth are common at diagnosis in paediatric IBD—especially Crohn’s disease—and identifying these issues early can guide nutrition and treatment planning. Most underweight children in this study...
The study shows pouchitis is a frequent postoperative problem in children after RPC‑IPAA and that many will still require advanced IBD medications, so surgery may not end medical therapy needs.
Consistent, accurate endoscopic scoring matters for treatment decisions and trial outcomes in pediatric IBD. If focused training meaningfully improves scoring—especially for SES‑CD—it could reduce variability in clinical...
Atypical presentations of Crohn's disease (abdominal wall abscess with enterocutaneous fistula) can delay diagnosis and treatment in children. Patients with communication difficulties may be at higher risk for missed or...
This study provides real-world evidence about using upadacitinib as a maintenance therapy in children with refractory Crohn’s disease — a group with limited treatment options.
People with Turner syndrome have higher rates of other autoimmune diseases; this case shows that celiac disease and ulcerative colitis can coexist and lead to growth and bone health problems.
Identifying a genetic cause (XIAP frameshift variant) helped explain why anti‑TNF drugs failed and why blocking IL‑12/23 with ustekinumab led to improvement; that connection could influence treatment choices for similar...
Refractory IBD in children is linked to growth and development problems, hospitalizations, and surgery; knowing treatment options after anti‑TNF failure matters for long‑term outcomes. The review highlights which...
This study gives real-world 52‑week data on upadacitinib maintenance in children with refractory Crohn's disease, showing meaningful remission rates but also notable adverse events. That balance is important for families...
VEO-IBD often presents with severe, extensive disease and can include monogenic causes and early hepatobiliary complications; knowing common presentations and early management patterns helps families and clinicians plan...
Disability and functional limitations (school, sports, travel, diet) are common early after pediatric IBD diagnosis and can persist for some children even after clinical remission. Recognizing and measuring disability...
Predicting which children with Crohn disease will need surgery — and roughly when — could help families and clinicians plan treatments, monitoring, and discussions about elective bowel resection earlier in the disease...
Delays and incomplete pre-referral screening are common in pediatric IBD and can affect how sick children are when they first see specialists. Better, standardized use of fecal calprotectin and abdominal ultrasound...
PSC commonly co-occurs with IBD in children; understanding clinical phenotypes and reliable monitoring tools helps families and clinicians track disease and plan follow-up.
Based on the title and source metadata, this appears to be a case report related to Crohn's disease and Pediatrics and family. The original article is from Frontiers in pediatrics.
MRE is a key radiation-free imaging tool for children with Crohn’s disease; this review summarizes its clinical utility and how it fits with other pediatric-focused diagnostic approaches in Japan.
Erythema nodosum can signal an underlying infection or systemic disease (including IBD) in children; recognizing common triggers helps guide evaluation and treatment.
A decreasing need for IBD-related surgery after pediatric diagnosis could mean fewer major operations and related recovery for children and young adults. It may reflect the growing use of advanced medical therapies in...
Noninvasive fecal calprotectin levels tracked with endoscopic disease activity in children with colonic Crohn's disease, suggesting FC could help reduce repeat endoscopies and better monitor treatment response.
Young people with IBD often struggle with health insurance knowledge during transition to adult care. Improving insurance literacy can help them access care and manage coverage decisions. This study suggests a brief,...
If confirmed, a pathology marker visible on routine biopsy (EGC patterns by SOX10 IHC) could help predict which children with ulcerative colitis are more likely to have improved mucosal inflammation over the first year,...
Shows molecular correlates (reduced IL‑17 signaling and IL‑1β) linked with mucosal healing after exclusive enteral nutrition in children with Crohn's disease, which may help researchers develop biomarkers or understand...
Pediatric-onset IBD can behave differently than adult-onset disease. Comparing conventional versus biologic approaches in children may help clarify relative effectiveness, safety, and impacts on growth and steroid...
PUC often behaves differently and more aggressively than adult-onset UC; understanding pediatric‑specific causes and treatments could lead to better, more effective therapies for children.
Imaging found increased visceral fat in children with Crohn's despite normal BMI, which could reveal inflammation-related risk not apparent from weight alone. Visceral adiposity was linked to markers of inflammation and...
Monogenic causes (especially IL-10RA mutations) are common in infant-onset IBD and are linked to more severe disease and higher mortality; early genetic testing and consideration of HSCT may change prognosis.
Children with newly diagnosed ulcerative colitis in this study commonly had reduced muscle mass (sarcopenia) at diagnosis, and the degree of muscle loss correlated with higher disease activity and inflammation....
This trial is testing risankizumab in children with moderate-to-severe Crohn’s disease to learn how the drug behaves in kids, whether it’s safe, and whether it reduces disease activity — information that could expand...
A national pediatric IBD registry from Colombia summarizes diagnosis age, disease types, treatment patterns (including rising biologic use), and outcomes—information that can inform families and clinicians about regional...
This trial tests whether oral vancomycin can help children with atypical ulcerative colitis or PSC-associated colitis and whether changes in gut bacteria or metabolites explain response. If effective and safe, it could...
This trial studies adalimumab safety and pediatric dosing in children with moderate–severe Crohn's disease, which is directly relevant to families and clinicians considering anti-TNF therapy for pediatric IBD.
The study raises the possibility that perinatal exposure to nanoplastics could have lasting, sex-specific effects on gut health and make adult offspring more susceptible to intestinal inflammation. This may be relevant...
The study suggests ADHD and autism are linked with slightly higher risk of more severe IBD events (including need for advanced therapies and, for UC, colectomy), which may help target monitoring and support for young...
Cure8 found this source from Journal of pediatric gastroenterology and nutrition, but the page could not be read reliably yet. It is tagged for Inflammatory bowel disease and Pediatrics and family. Open the original...
Trends in treatments for children with IBD can affect hospitalization and surgical needs. Noting rising use of biologics (infliximab) alongside fewer hospitalizations may be important for families and clinicians tracking...
Thalidomide can help treat refractory pediatric IBD but causes peripheral neuropathy. Knowing a cumulative-dose threshold linked to neuropathy could help clinicians balance benefit and neurotoxicity risk.
C. difficile can cause or complicate diarrhoea in children with IBD, so understanding test positivity in this group helps clinicians interpret results and decide when to investigate or treat. The study suggests...
Malnutrition and growth failure at diagnosis are common in children with IBD—especially Crohn’s—and can indicate higher inflammatory burden. Monitoring and addressing nutrition and growth is important because most...
Coordinated transition to adult gastroenterology affects continuity of care for children with chronic GI conditions such as IBD; improvements could reduce gaps in treatment and support during young adulthood.
Based on the title and source metadata, this appears to be a patient education related to Inflammatory bowel disease and Pediatrics and family. The original article is from Journal of Pediatric Gastroenterology and...
Patients with CGD can develop an IBD-like condition that is hard to treat because many immunosuppressive drugs raise infection risk. This trial suggests thalidomide may reduce intestinal inflammation in CGD-IBD without...
Both EEN and the Crohn’s disease exclusion diet are used to induce remission in children with Crohn’s disease. Evidence that they perform similarly through 52 weeks may help families and clinicians choose the approach...
