Colonoscopy, endoscopy, fecal calprotectin, CRP, imaging, intestinal ultrasound, and monitoring research.
Page 28 of 33 · 1559 articles
Patients and clinicians choosing first‑line biologic therapy for ulcerative colitis may find evidence here that vedolizumab can provide sustained clinical benefit and a favorable safety profile in a biologic‑naïve...
Subcutaneous infliximab may let children on infliximab avoid regular IV infusions while keeping drug levels high and maintaining remission. Results are relevant to families and clinicians considering switching pediatric...
This large, population-based study tests whether exposure to outdoor artificial light at night is linked to getting IBD or to later health-care use. Understanding environmental factors that might influence IBD risk or...
The study uses single-cell RNA sequencing to pinpoint genes and regulatory networks that might help explain IBD biology and suggest new biomarkers or repurposed drugs. That information could guide future research toward...
Cure8 found this source from BMC Gastroenterology, but the page could not be read reliably yet. It is tagged for Inflammatory bowel disease and Tests and monitoring. Open the original article for the full details.
New PET tracers like FAPI could better detect fibrosis and stromal activity than standard FDG-PET, which may improve imaging of fibrostenotic Crohn's disease. For people with IBD, improved imaging might eventually help...
Point-of-care intestinal ultrasound (IUS) showed strong agreement with follow-up tests and often changed management the same day in a New Zealand IBD cohort. Patients and clinicians may be able to use IUS to monitor...
New or improved fluorescent probes could enable more sensitive, noninvasive imaging of biochemical changes in the gut, which may aid research, earlier diagnosis, or monitoring of IBD and colorectal cancer.
Bowel urgency is a common, disruptive UC symptom; this trial analysis shows urgency improvements with etrasimod track with clinical remission, endoscopic improvement, better quality of life, and lower inflammatory...
Many patients and clinicians are interested in subcutaneous infliximab because it can be more convenient than IV infusions and may change drug exposure.
Extrapulmonary TB can be triggered or revealed during immunosuppressive biologic therapy and may mimic other causes of liver injury; early recognition and TB-specific testing are important for timely treatment and to...
IL-38 and a genetic variant (rs7599662) were linked to ulcerative colitis in this study, suggesting a possible new biomarker or therapeutic target. If validated, this could help researchers better understand UC...
This study will collect real-world data on adults with moderate-to-severe ulcerative colitis who start upadacitinib, tracking symptom remission and imaging response over one to two years — information that can help...
This trial tests several investigational long-acting antibody treatments (as monotherapies and combinations) for adults with moderate to severe ulcerative colitis using histologic and clinical remission endpoints —...
This trial could expand approved treatment options for children with moderate to severe UC by testing the safety, pharmacokinetics, and maintenance dosing of risankizumab in pediatric age groups.
A new NIR-II-emitting MOF probe could enable deeper, higher-contrast fluorescence imaging of inflamed gut tissue and might be developed as a targeted delivery/imaging agent relevant to IBD research and future...
The findings suggest that over three decades more patients receive medical prevention after ileocolic resection — including thiopurines and biologics — and that rates of needing a second surgery have fallen. This matters...
People with Crohn’s disease and fibrotic ileocecal valve strictures sometimes face surgery when endoscopic access is blocked by polypoid tissue. A new endoscopic approach (ICVP) aims to remove obstructing tissue so...
Shows real-world long-term outcomes in a large Chinese UC cohort and highlights that baseline disease activity predicts need for escalation and colectomy risk; points to opportunities to improve treat-to-target care.
This study describes how IBD presents and early outcomes in children at a tertiary center, noting high rates of inflammation, nutritional problems, and early flares. Findings may help families and clinicians understand...
Respiratory diseases (COPD, asthma, bronchiectasis) and IBD appear to occur together more often than expected. If you have IBD, especially Crohn’s, you may be at higher risk for some obstructive lung diseases, and people...
The study compares two oral steroid therapies used to induce remission in outpatient ulcerative colitis and reports similar short-term efficacy but different safety profiles — information that can inform treatment...
People with IBD and their clinicians want ways to predict which advanced therapy will work best. This review summarizes current evidence and shows that, despite many studies, no biomarker is reliably ready for routine...
Emerging adults with IBD face distinct challenges managing care. The study shows people diagnosed as children may know about their disease but still need help with practical self-management tasks — a gap that can affect...
The FDA label for XELJANZ/XELJANZ XR (tofacitinib) highlights serious safety risks and monitoring steps relevant to people with ulcerative colitis and other autoimmune conditions who may be using or considering this JAK...
The FDA/DailyMed label defines approved uses and official dosing guidance for prednisone, a corticosteroid commonly used to treat moderate-to-severe inflammatory conditions including ulcerative colitis and regional...
The study identifies candidate metabolites that may underlie gut–brain biochemical crosstalk during colitis, which could point to early biomarkers or mechanistic targets relevant to IBD-related brain effects.
Endoscopy in this pediatric multicenter series found a high diagnostic yield and confirmed IBD and other treatable conditions; this matters for families and clinicians in resource-limited settings because improving...
A coordinated national research network can accelerate studies that matter to people with IBD—like tracking real-world disease patterns, testing diet and psychosocial approaches, improving monitoring with biomarkers and...
Algorithms guide how UC is diagnosed and monitored (endoscopy, labs, fecal markers, imaging) and when to escalate to surgery or other interventions; that affects surveillance, treatment choices, and complication...
CMV can complicate acute colitis in people with IBD and may change treatment decisions; knowing which tests are most sensitive or specific helps clinicians decide how to work up suspected CMV colitis during...
This study synthesizes randomized trial evidence about the role of gut microbiota in ulcerative colitis and whether fecal microbiota transplantation (FMT) can help induce remission. People with UC may encounter FMT as a...
This registry will provide real-world data on how etrasimod is used and performs in routine clinical practice in China, including patient characteristics, symptom trajectories, safety, and healthcare costs. Real-world...
People with Crohn’s disease facing surgery may have varying risks of complications; better biomarkers and models could help tailor perioperative care and decision-making. The review signals active research toward more...
AI tools are being tested to speed capsule endoscopy reading and help triage cases, which matters to people with IBD because capsule endoscopy is commonly used to detect small-bowel ulcers and inflammation.
People with IBD face an elevated lifetime risk of colitis-associated cancer; improved detection and risk prediction could lead to earlier treatment and better outcomes. AI could make surveillance more accurate and...
Cure8 found this source from Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, but the page could not be read reliably yet. It is tagged...
If you have ulcerative colitis, the study suggests that TCM pattern labels (DCSR vs PXSY) align with measurable differences in inflammation and tissue damage, which could influence personalized symptom assessment or...
Patients, families, and clinicians may care because the study shows pediatric-onset IBD is more often Crohn's and that children begin advanced therapies earlier than adults. The adult persistence data for vedolizumab and...
Nanoparticle technologies could eventually enable more targeted drug delivery and improved imaging for IBD and related GI diseases, which may lead to better diagnosis and less systemic side effects. However, translation...
Measuring both how severe inflammation is and how much of the colon is affected could give a fuller picture of disease burden than current focal endoscopic scores. For patients with UC, that may affect risk assessment...
The work models how Mycobacterium avium can provoke epithelial inflammation similar to Crohn's disease, pointing to possible molecular links between infection and CD-like pathology that could guide future research.
Researchers are exploring methods to make probiotic therapies more stable through the digestive tract and to deliver anti-inflammatory molecules directly where intestinal inflammation produces high reactive oxygen...
CMV reactivation can worsen outcomes in active UC and influence treatment choices; clinicians and patients may benefit from additional, easy-to-measure markers that flag higher risk of tissue CMV and prompt targeted...
People with long-standing ulcerative colitis face an increased risk of colorectal cancer; this study highlights PPARGC1A as a gene that may be downregulated early in that progression, which could eventually help identify...
A blood biomarker that rises with active ulcerative colitis could help patients and clinicians monitor disease activity without relying solely on invasive tests. This study reports that serum type 23 collagen ectodomain...
This large, population-based study suggests people with Crohn's disease have modestly higher overall mortality than matched controls and higher deaths from specific causes (colorectal cancer, renal disease, non-Hodgkin...
Noninvasive blood biomarkers that track IBD activity could reduce reliance on repeat endoscopy. If validated, serum galectin‑3 might complement fecal calprotectin and CRP to help identify active disease.
