Nutrition, food, supplements, exercise, sleep, stress, and lifestyle research for Crohn's disease and IBD.
Page 14 of 24 · 1124 articles
The review links gut microbiota changes and mucosal immune responses across IBD and IgA nephropathy, suggesting that gut dysbiosis may contribute to systemic immune-driven disease.
This review may help patients and clinicians understand how long-lasting changes in bacterial metabolism could contribute to IBD relapse and point toward future microbiome-targeted therapies aimed at restoring resilient...
The video demonstrates a bowel-preserving robotic surgical technique for ileal strictures in Crohn's disease that could help surgeons perform technically demanding intracorporeal suturing and preserve bowel length.
Vitamin D appears linked to immune regulation, gut barrier health, and the microbiome—processes relevant to IBD and other intestinal disorders. Understanding this could affect how clinicians monitor and study vitamin D...
Many people with IBD experience persistent fatigue, pain and faecal incontinence even when inflammation is controlled; this programme tested a supported online self-management approach to help those symptoms and assessed...
This trial tests a mushroom-derived dietary supplement in people with mild-to-moderate UC or colonic/ileal Crohn's disease, measuring symptoms, fecal biomarkers, and endoscopic activity—outcomes that matter to patients...
This animal study suggests Antarctic krill oil may reduce inflammation and weight loss in a mouse model of ulcerative colitis and works alongside changes in gut microbiota and metabolites—findings that could inform...
Self-management is central to living with UC, and this framework gives a structured way to design support that targets behaviors people need to manage the disease.
This paper offers a multi-layered ecological perspective on UC-associated microbiome changes that could help researchers identify which microbial functions or taxa are driven more by random processes versus selection in...
Fear of movement (kinesiophobia) can reduce physical activity and worsen quality of life for people with IBD.
If dietary oxalate influences gut inflammation, it could be a modifiable dietary factor for some people with IBD and might help explain variability in symptoms. The study points to transporters as potential markers of...
IBD patients often face high psychological burden; knowing whether MBCT is acceptable and feasible helps patients and clinicians weigh it as a support option. Practical barriers (time, fatigue, disease activity) and...
A probe that detects both ATP and hypochlorite may offer a more specific optical marker of oxidative/inflammatory activity in IBD models, which could aid research into disease mechanisms and future diagnostic approaches.
GLP-1 receptor agonists — drugs commonly used to treat obesity and metabolic disease — may help patients with IBD by reducing visceral fat and improving cardiometabolic health.
People labelled with IBS-D may actually have treatable organic conditions that require different tests and treatments; avoiding diagnostic mistakes can speed appropriate care and reduce unnecessary symptom-focused...
Understanding how the gut virome shapes regulatory T cells could reveal new biomarkers or therapeutic targets for IBD and related systemic immune diseases. This may help explain unexplained flares or individual...
The study suggests a rice bran extract might reduce colitis severity in rats by shifting gut microbiota and dampening TLR4/NF-κB–driven inflammation, a pathway relevant to human IBD research.
Non-invasive fecal lipid markers could help differentiate UC from CD and improve diagnostic molecular profiling in IBD if validated, which may be useful for patients and clinicians seeking less-invasive diagnostic tools.
Someone with Crohn’s disease and limited remaining small intestine may face high-risk surgical choices. This case report suggests a specialized oral supplement used with conservative care was associated with fistula...
This study suggests noninvasive vagus nerve stimulation (taVNS) can reduce colonic inflammation and change immune signals regionally in a mouse model of ulcerative colitis—supporting a possible neuroimmune approach worth...
Micronutrient deficiencies are common in IBD and can worsen anemia, healing, and neurologic function. This study shows inpatient testing focuses on B12 while missing other commonly deficient nutrients (B1, B6, zinc),...
Identifies gene and microbiome patterns linked to progression from inflammation to irreversible bowel fibrosis in Crohn’s disease, which could eventually help predict who is at higher risk and inform prevention...
Fibrosis (irreversible bowel scarring) is a major cause of surgery in Crohn’s disease. This study points to molecular and microbiome patterns that may help predict or distinguish fibrosis from active inflammation, which...
The work points to measurable molecular and microbial patterns that may help distinguish treatable inflammation from progressive fibrosis and suggests AI could aid in building predictive tools from limited samples —...
The probe targets azoreductase-driven hypoxia, a mechanism linked to ulcerative colitis and other hypoxia-associated diseases; a reliable real-time imaging method could help research and eventually guide treatments.
Patients with IBD commonly change or restrict their diets and often want reliable guidance. This study tested automated personalized feedback plus an online nutrition portal and found improved food-related quality of...
This correction updates duplicated data points and clarifies methods in a preclinical synthetic-biology study about engineered materials that secrete therapeutic proteins for IBD, which affects interpretation and...
Malnutrition risk and nutrition insecurity can affect symptom management and overall health for people with IBD. Understanding barriers and supports helps target practical services (dietitians, social resources, digital...
The paper describes a preclinical demonstration that a plant-derived compound reduced inflammation and changed gut microbiota and metabolite profiles in a mouse colitis model, suggesting a possible route for future...
Targeted release of mesalamine to the colon could increase local drug levels and reduce upper-GI exposure and systemic side effects. New delivery platforms may improve effectiveness for ulcerative colitis without...
The study suggests a probiotic strain (Lactobacillus plantarum) reduced inflammation and prolonged remission in multiple mouse models of Crohn’s-like disease, indicating microbiome-based approaches might be promising to...
The study identifies a possible molecular mechanism (THRIL downregulation and inhibition of p38 MAPK/NF-κB) by which a traditional Chinese medicine preparation reduced inflammation in mouse and cell models of colitis,...
Bile acids shaped by gut microbes can influence inflammation and metabolism, so understanding these pathways could lead to new biomarkers or treatments relevant to people with IBD.
Shared gut microbiome shifts across autoimmune diseases could suggest common microbial factors relevant to immune regulation and might eventually inform diagnostics or therapies relevant to people with IBD.
Back-to-school planning can reduce emergencies and missed care for students with chronic conditions, including Crohn’s disease. Preparing plans, communicating with school or campus staff, and knowing where to get care...
AI could help make IBD assessments (endoscopy, histology, imaging, biomarkers) more objective and faster, which may improve monitoring, treatment selection, and early detection of complications for people with Crohn’s...
The study connects common dietary patterns to self‑reported IBD activity and quality of life, suggesting diet may be linked to symptom burden for people with Crohn’s disease and UC/IBDU.
If you have IBD, the mouth and gums may be part of shared inflammatory pathways with your gut. Periodontitis is associated with higher odds of having IBD in cross-sectional studies and has a modest link to later...
The trial tests two low-cost adjuncts — a Lactobacillus probiotic and a multi–trace-element supplement — added to biologic-based standard care to see if they help maintain remission in ulcerative colitis. If effective,...
Smart, stimuli-responsive nanocarriers could one day allow IBD treatments to act more precisely in the gut and limit side effects; that may matter to people hoping for better-targeted therapies or fewer systemic...
This study links population-level IBD epidemiology to gut microbiome changes and proposes a microbial risk score that might help detect or surveil IBD patterns. That could inform future biomarker development or...
This review suggests Aloe vera polysaccharides could support gut barrier repair, microbiome balance, and immune regulation—mechanisms relevant to IBD inflammation and healing. However, evidence is mainly preclinical and...
Nanotechnology approaches aim to improve how cytokine-targeting therapies are delivered in IBD, which could reduce systemic exposure and immunogenicity and increase local effectiveness.
The study suggests a natural flavonoid (DHQ) can protect against DSS-induced colitis in mice and identifies a specific phospholipase-related pathway that may link phospholipid breakdown to epithelial barrier...
Intestinal fibrosis causes strictures that often need surgery and has few effective medical treatments; linking the microbiome to fibrogenesis suggests new prevention or treatment strategies that could reduce surgery...
People with IBD need more than flare control: they also require proactive preventive care (vaccination, cancer screening, bone and nutrition checks, and mental health support) because of risks from chronic inflammation...
Faecal microbiota transfer is being tested in a large Phase 3 trial as a possible new treatment approach for active ulcerative colitis, and this study also looks at safety and how the therapy changes the gut microbiome...
The study presents a gut-targeted bispecific that aims to both block gut-homing/inflammatory signals and activate epithelial repair — a combined approach that could reduce systemic immunosuppression while promoting...
