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Articles for parents and caregivers navigating pediatric IBD news, family decisions, school issues, and child health updates.

Page 3 of 7 · 307 articles

Cumulative thalidomide exposure, peripheral neuropathy, and clinical outcomes in pediatric and very early-onset inflammatory bowel disease: a retrospective cohort study.
Clinics (Sao Paulo, Brazil)

Cumulative thalidomide exposure, peripheral neuropathy, and clinical outcomes in pediatric and very early-onset inflammatory bowel disease: a retrospective cohort study.

Thalidomide can help treat refractory pediatric IBD but causes peripheral neuropathy. Knowing a cumulative-dose threshold linked to neuropathy could help clinicians balance benefit and neurotoxicity risk.

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Clostridioides difficile in Paediatric Inflammatory Bowel Disease: A Retrospective Cross-Sectional Analysis of the East London Region.
Journal of paediatrics and child health

Clostridioides difficile in Paediatric Inflammatory Bowel Disease: A Retrospective Cross-Sectional Analysis of the East London Region.

C. difficile can cause or complicate diarrhoea in children with IBD, so understanding test positivity in this group helps clinicians interpret results and decide when to investigate or treat. The study suggests...

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Nutritional Status and Linear Growth at Diagnosis and Their Association with Clinical Outcomes in Paediatric Inflammatory Bowel Disease: A Multicentre Cohort Study
Nutrients

Nutritional Status and Linear Growth at Diagnosis and Their Association with Clinical Outcomes in Paediatric Inflammatory Bowel Disease: A Multicentre Cohort Study

Malnutrition and growth failure at diagnosis are common in children with IBD—especially Crohn’s—and can indicate higher inflammatory burden. Monitoring and addressing nutrition and growth is important because most...

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Transition of children with chronic gastrointestinal and liver disease to adult care: A multicentre Asian survey of paediatric gastroenterologists
Journal of Pediatric Gastroenterology and Nutrition

Transition of children with chronic gastrointestinal and liver disease to adult care: A multicentre Asian survey of paediatric gastroenterologists

Coordinated transition to adult gastroenterology affects continuity of care for children with chronic GI conditions such as IBD; improvements could reduce gaps in treatment and support during young adulthood.

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Best practices for prior authorization in pediatric inflammatory bowel disease: A practical multidisciplinary roadmap
Journal of Pediatric Gastroenterology and Nutrition

Best practices for prior authorization in pediatric inflammatory bowel disease: A practical multidisciplinary roadmap

Based on the title and source metadata, this appears to be a patient education related to Inflammatory bowel disease and Pediatrics and family. The original article is from Journal of Pediatric Gastroenterology and...

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Exclusive enteral nutrition versus the Crohn's disease exclusion diet for remission induction in pediatric Crohn's disease: 52-week study.
Journal of pediatric gastroenterology and nutrition

Exclusive enteral nutrition versus the Crohn's disease exclusion diet for remission induction in pediatric Crohn's disease: 52-week study.

Both EEN and the Crohn’s disease exclusion diet are used to induce remission in children with Crohn’s disease. Evidence that they perform similarly through 52 weeks may help families and clinicians choose the approach...

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Switching Between Anti-TNFs and Other Biologic Drugs in Paediatric Inflammatory Bowel Disease: A Narrative Review and Practical Clinical Guide.
Journal of inflammation research

Switching Between Anti-TNFs and Other Biologic Drugs in Paediatric Inflammatory Bowel Disease: A Narrative Review and Practical Clinical Guide.

Switching biologics is a frequent and consequential decision in children with IBD; using TDM and a mechanism‑based approach can help choose whether to optimize, switch within class, or change drug class.

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Autoimmune and lymphoproliferative outcomes after Kawasaki disease: a 20-year population-based cohort study.
European journal of pediatrics

Autoimmune and lymphoproliferative outcomes after Kawasaki disease: a 20-year population-based cohort study.

If you or a child had Kawasaki disease, this study suggests there may be a higher long-term chance of certain skin autoimmune conditions (psoriasis, vitiligo) but no clear increase in IBD or several other autoimmune...

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Exploring the impact of DEP on pediatric Crohn's disease using machine learning and molecular docking methods.
Frontiers in pediatrics

Exploring the impact of DEP on pediatric Crohn's disease using machine learning and molecular docking methods.

Researchers used machine learning and molecular docking plus small animal tests to link a common plasticizer (DEP) with molecular changes seen in pediatric Crohn’s disease. This could point to environmental exposures...

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Dual biologic therapy in inflammatory bowel disease, a retrospective cohort study of vedolizumab and anti-tumor necrosis factor alpha therapy in children.
Journal of pediatric gastroenterology and nutrition

Dual biologic therapy in inflammatory bowel disease, a retrospective cohort study of vedolizumab and anti-tumor necrosis factor alpha therapy in children.

This study reports that combining an anti-TNF-α drug with vedolizumab helped many children with IBD who failed single-biologic therapy achieve clinical, endoscopic, and histologic improvement. It also notes serious...

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Patient-derived intestinal organoids in pediatric inflammatory bowel disease: applications in disease modeling and therapeutic response prediction
Korean Journal of Pediatrics

Patient-derived intestinal organoids in pediatric inflammatory bowel disease: applications in disease modeling and therapeutic response prediction

Patient-derived intestinal organoids offer a human-relevant platform that could improve understanding of pediatric IBD biology and help predict individual treatment responses — potentially reducing trial-and-error...

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Anaemia in patients diagnosed with paediatric-onset inflammatory bowel disease: A Danish nationwide cohort study.
Journal of pediatric gastroenterology and nutrition

Anaemia in patients diagnosed with paediatric-onset inflammatory bowel disease: A Danish nationwide cohort study.

Anaemia is a common and impactful complication in children diagnosed with IBD; knowing how often it occurs, which subtypes are most frequent, and its link with disease activity can guide monitoring and management...

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Longitudinal effects of a nurse-led self-management intervention in inflammatory bowel disease.
Minerva gastroenterology

Longitudinal effects of a nurse-led self-management intervention in inflammatory bowel disease.

Self-management and nursing-led psychoeducation may improve quality of life and reduce depressive symptoms for people with IBD. Family support appears to influence who benefits most, which could help tailor care.

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Reporting and representation of participant race, ethnicity, and sex in pediatric IBD clinical trials.
Inflammatory bowel diseases

Reporting and representation of participant race, ethnicity, and sex in pediatric IBD clinical trials.

Clinical trials shape available treatments and evidence; if groups of children (by race, ethnicity, or sex) are underrepresented, study results may not reflect how treatments work for them. This paper identifies...

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Early Use of Anti-Tumor Necrosis Factor Therapy for Penetrating Complications in Children With Crohn's Disease: Multicenter Insight to a Challenging Clinical Problem
The American Journal of Gastroenterology

Early Use of Anti-Tumor Necrosis Factor Therapy for Penetrating Complications in Children With Crohn's Disease: Multicenter Insight to a Challenging Clinical Problem

Cure8 could only read part of this source from The American Journal of Gastroenterology, so this card uses cautious topic tags instead of a full summary. It is tagged for Crohn's disease, Inflammatory bowel disease, and...

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A Multicenter, Prospective, Long-term, Observational Registry of Pediatric Patients With Inflammatory Bowel Disease
ClinicalTrials.gov

A Multicenter, Prospective, Long-term, Observational Registry of Pediatric Patients With Inflammatory Bowel Disease

This registry will track long-term safety and clinical outcomes in children with IBD, with a focus on infliximab (an anti‑TNF biologic) versus non‑biologic therapies. Long follow-up could help identify uncommon or late...

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Shaping the research agenda of pediatric gastroenterology, hepatology, and nutrition: The proposal from a SIGENP expert groups
PubMed Central

Shaping the research agenda of pediatric gastroenterology, hepatology, and nutrition: The proposal from a SIGENP expert groups

A strategic, pediatric-focused research agenda helps target studies where children with IBD and related conditions most need better diagnostics, biomarkers, and treatments. Prioritizing multi-center registries and...

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Modifiable lifestyle factors in early life and inflammatory bowel disease risk in two birth cohorts.
Journal of Crohn's & colitis

Modifiable lifestyle factors in early life and inflammatory bowel disease risk in two birth cohorts.

The study suggests that modifiable early-life factors (feeding, antibiotic exposure, activity, BMI, smoke exposure, delivery mode, diet) may influence the later risk of IBD, especially Crohn's disease, which could be...

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Dyspareunia and heavy menstrual bleeding as clinical predictors of concomitant endometriosis in Inflammatory Bowel Disease: A multidisciplinary prospective study.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

Dyspareunia and heavy menstrual bleeding as clinical predictors of concomitant endometriosis in Inflammatory Bowel Disease: A multidisciplinary prospective study.

Endometriosis may coexist with IBD and can cause pelvic pain, painful sex, and heavy periods—symptoms that may be mistaken for bowel disease activity. Identifying endometriosis could change evaluation and management for...

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A Study of How the Medicine Called "Etrasimod" Works in Children With the Gut Disease Called Ulcerative Colitis
ClinicalTrials.gov

A Study of How the Medicine Called "Etrasimod" Works in Children With the Gut Disease Called Ulcerative Colitis

A pediatric Phase 2 trial testing etrasimod could expand treatment options for children with moderately to severely active ulcerative colitis if later shown safe and effective. Families of affected children and their...

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Efficacy and Safety of Upadacitinib in Refractory Very-Early-Onset Ulcerative Colitis: A Case Report.
Journal of paediatrics and child health

Efficacy and Safety of Upadacitinib in Refractory Very-Early-Onset Ulcerative Colitis: A Case Report.

Cure8 found this source from Journal of paediatrics and child health, but the page could not be read reliably yet. It is tagged for Ulcerative colitis, Inflammatory bowel disease, and Upadacitinib. Open the original...

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Takayasu Arteritis in a Child with Chronic Active Proctitis of Unspecified Etiology: A Case Report with Diagnostic Challenges and Literature Review.
Journal of visualized experiments : JoVE

Takayasu Arteritis in a Child with Chronic Active Proctitis of Unspecified Etiology: A Case Report with Diagnostic Challenges and Literature Review.

People with pediatric IBD-like intestinal inflammation, or caregivers, may encounter overlapping autoimmune conditions such as large-vessel vasculitis; recognizing that intestinal biopsy can be nondiagnostic is...

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Aminosalicylate use Increases Corticosteroid Exposure and Decreases Biologic Durability in Pediatric Crohn's Disease.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Aminosalicylate use Increases Corticosteroid Exposure and Decreases Biologic Durability in Pediatric Crohn's Disease.

This study suggests that using 5‑ASA drugs early in children with Crohn’s disease was common but linked to more steroid use, delayed biologic treatment, and lower biologic durability — outcomes that matter for long‑term...

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Microbial and functional shifts between flare and remission in a single-center cohort of children with inflammatory bowel disease.
World journal of clinical pediatrics

Microbial and functional shifts between flare and remission in a single-center cohort of children with inflammatory bowel disease.

The study links changes in gut microbes and microbial functions with disease activity in children with IBD, suggesting the microbiome may play a role in recovery and could be a target to help sustain remission.

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Ultrasound Features Associated with Activity of Perianal Fistulas in Pediatric Patients with Crohn's Disease.
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine

Ultrasound Features Associated with Activity of Perianal Fistulas in Pediatric Patients with Crohn's Disease.

Perianal fistulas are a common and morbid complication of Crohn's disease in children; a reliable, less burdensome imaging tool could help assess severity and monitor response to therapy more often than MRI.

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Association between Ulcerative Colitis, mental health, and Quality of Life in a Pakistani cohort: A cross-sectional analysis
PLOS One

Association between Ulcerative Colitis, mental health, and Quality of Life in a Pakistani cohort: A cross-sectional analysis

The study links worse UC activity with higher rates of anxiety and depression and with poorer quality of life among patients in Pakistan, suggesting mental-health screening could be relevant to overall disease...

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Early‐life adverse events and risk of inflammatory bowel disease: A Scandinavian birth cohort study
Journal of Pediatric Gastroenterology and Nutrition

Early‐life adverse events and risk of inflammatory bowel disease: A Scandinavian birth cohort study

Parents and clinicians may wonder whether stressful events in early life increase a child’s long-term IBD risk. This large prospective study found no evidence that the measured early maternal or family adverse events...

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Idiopathic Acute Pancreatitis in Paediatric Inflammatory Bowel Disease: Clinical Features and Outcomes in a Retrospective Single-Centre Study.
Journal of paediatrics and child health

Idiopathic Acute Pancreatitis in Paediatric Inflammatory Bowel Disease: Clinical Features and Outcomes in a Retrospective Single-Centre Study.

Children with IBD can develop idiopathic acute pancreatitis that is often mild but may recur; knowing this helps families and clinicians monitor and manage pancreatic symptoms during active disease and after surgery.

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Colorectal Inflammatory Bowel Disease in Sub-Saharan Africa: Diagnostic Challenges and Systemic Care Constraints.
The American surgeon

Colorectal Inflammatory Bowel Disease in Sub-Saharan Africa: Diagnostic Challenges and Systemic Care Constraints.

The review highlights that colorectal IBD is under-recognized and often mistaken for infectious colitis in sub‑Saharan Africa due to limited diagnostic and specialist resources, which can delay appropriate care.

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