Resection, ostomy, J-pouch, strictureplasty, fistula, abscess, and other procedure-related updates.
Page 8 of 11 · 490 articles
A nationwide clinician survey identifies major variation in how acute severe ulcerative colitis is diagnosed, monitored, and when rescue therapy or surgery is used — differences that can affect patient outcomes and...
A successful Phase 3 trial could add guselkumab — an IL-23–targeting biologic — as a treatment option for people with moderate to severe Crohn's disease, especially those who haven’t responded to prior therapies.
A humanized DSS colitis model that recreates human T cell and myeloid responses could make preclinical testing of human-specific biologics (like anti-TNF antibodies) more relevant to people with IBD.
Early company-reported clinical responses in special-access patients and planned Phase 2 trials could signal a new stem-cell therapy approach advancing for fistulising Crohn’s disease — a complication that can be hard to...
Noninvasive TUS can help detect small-bowel inflammation and stenosis in Crohn's disease with high specificity, potentially reducing the need for immediate invasive testing. However, its sensitivity varies by small-bowel...
People with IBD and their clinicians often rely on MRI for monitoring disease; knowing that MRI techniques can also detect other bowel problems helps explain imaging choices and what radiologists may be looking for when...
NICE’s patient summary explains care expectations for people with Crohn’s disease, emphasising shared decision-making, symptom control, and understanding treatment options — practical points that affect everyday...
The record concerns a planned surgical approach using a patient's own bone marrow–derived stem cells to try to heal fistulating perianal Crohn's disease—an often hard-to-treat complication that substantially affects...
Perianal fistulizing Crohn’s disease causes delayed healing and high recurrence after surgery. This study suggests a specific time-guided external traditional therapy may speed wound healing, reduce inflammation, and...
For people with perianal Crohn’s disease, better bedside imaging that distinguishes phlegmon from abscess can change surgery plans and may avoid unnecessary wide drainage procedures.
If surgeons can safely perform a primary bowel reconnection when they encounter an intra-abdominal abscess during Crohn surgery, some patients may avoid a temporary stoma and its associated morbidity.
People with IBD and their clinicians often worry that anorectal surgery like hemorrhoidectomy could cause complications, flares, or loss of continence. This study suggests that, in a selected multicenter European cohort,...
If a serious infection occurs while on an anti‑TNF drug, patients and clinicians face difficult decisions about when and whether to restart biologic therapy. This case shows one example where switching to mirikizumab...
Standardizing inpatient IBD care with a defined index improved measurable adherence at the authors’ center, which could reduce variability in the care patients receive during hospital stays.
ECCO 2026 presented multiple studies that could change IBD care across prevention, medical therapy (including pediatric data), complication‑directed strategies (perianal fistula), and technology‑assisted monitoring....
Perianal fistulizing Crohn's disease is difficult to treat and many patients have failed anti-TNF therapy. Evidence that ustekinumab achieves high clinical fistula response and remission rates in a real-world multicenter...
People with IBD often take biologics and may need or want implant-based breast surgery.
Understanding which patients are at higher risk for serious complications after IBD surgery can help patients and clinicians weigh risks, plan preoperative optimization, and guide research into preventive strategies.
This study reports real-world outcomes with granulocyte and monocyte adsorptive apheresis (GMA) in patients with refractory IBD, showing steroid-free remission by week 14 in about one-third of patients and continued...
If reliable, an earlier day‑3 PUCAI cutoff could help identify children with flare‑related ASUC who are unlikely to respond to IV steroids and who may benefit from earlier planning for second‑line therapy rather than...
Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Procedures and surgery. The original article is from ANZ Journal of Surgery.
An infectious cause (amebic colitis) can mimic IBD on colonoscopy and imaging, even without symptoms; misdiagnosis could delay correct treatment.
Stoma creation and whether it can later be closed greatly affects daily life and planning for people with Crohn's disease.
Perianal inflammatory lesions are common in Crohn's disease and may mark higher cancer-related risk; knowing their association with worse survival after anorectal cancer surgery can inform discussions about prognosis and...
A simple blood ratio measured before surgery (LCR) may help predict which children with UC are at higher risk of surgical site infection after IPAA, potentially guiding preoperative care.
Findings are relevant because they describe outcomes and predictors of conversion for a minimally invasive surgery option (SILS) that some patients with Crohn's disease may be offered. Understanding risk factors can help...
Elevated pancreatic enzymes are relatively common in IBD and can reflect very different conditions (benign asymptomatic elevations, pancreatitis variants, or autoimmune pancreatitis). Recognizing phenotype-specific...
Perianal fistulas are a serious complication of Crohn’s disease with limited high-quality trial evidence. This randomized trial suggests ustekinumab may increase the chance of combined clinical and MRI remission at 12...
This trial is testing whether adding vedolizumab after autologous stem cell transplant can improve remission rates for people with severe Crohn's disease that has failed multiple therapies.
Based on the title and source metadata, this appears to be a case report related to Ulcerative colitis, Colorectal cancer, and Procedures and surgery. The original article is from Gastroenterology report.
An ELANE mutation causing severe congenital neutropenia can present with neutropenic enterocolitis that mimics ulcerative colitis. Recognizing neutropenia and pursuing genetic testing can prevent misdiagnosis and change...
Perianal fistulizing Crohn's disease is a disabling complication; a subcutaneous form of infliximab could lower treatment burden and expand options if its effectiveness and safety in this specific setting are confirmed.
If organoid transplantation can be translated to people, it could offer a new way to repair inflamed colonic lining and promote mucosal healing when current therapies are insufficient. The approach also highlights links...
A rare but serious colitis linked to ocrelizumab is described and managed successfully with ciclosporin in a steroid‑refractory case; this may be relevant to clinicians caring for patients on B‑cell–depleting therapy.
An externally validated, simple prediction score could help identify patients unlikely to need early aggressive treatment and inform shared decision-making about monitoring and therapy.
For patients and clinicians facing steroid- and infliximab-refractory acute severe ulcerative colitis, upadacitinib may be a third-line medical option that can produce rapid symptom and CRP improvement and allow some...
LCH can present like perianal Crohn's disease and may be missed if biopsies and molecular testing are not performed. Correct diagnosis changes treatment and prompts systemic staging for other malignancies.
Cure8 indexed source-provided abstract text from JAMA, but this record did not meet the threshold for a full Cure8 brief. It is tagged for Ulcerative colitis, Inflammatory bowel disease, and Procedures and surgery.
This Phase 2a trial tested a new investigational drug, tulisokibart, in people with moderately to severely active Crohn’s disease who have not done well on prior therapies — so patients and clinicians watching new...
The study will prospectively evaluate how often dysplasia occurs, how lesions look and behave after endoscopic resection, and what factors predict local or distant recurrence—information that could change surveillance...
Findings help patients and surgical teams set expectations before laparoscopic ileocecal resection: certain disease patterns (fistulizing) and older age raise the chance of conversion, which can increase length of stay...
Automated, sequence-robust MRI measures could help standardize detection and localization of perianal anoperineal lesions in Crohn’s disease, which is relevant for diagnosis and management of perianal complications.
The review examines whether removing the appendix could change the course of ulcerative colitis — a potential surgical option that might lower colectomy or hospitalization risk in some scenarios but also carries...
For people with ulcerative colitis treated with infliximab for acute severe disease, whether to keep giving systemic corticosteroids afterward affects infection risk, steroid side effects, and disease control.
Patients with Crohn's disease had a higher adjusted risk of periprosthetic joint infection within 90 days after elective joint replacement, while ulcerative colitis did not. This difference could affect preoperative risk...
CMUSE can closely mimic Crohn's disease and may require surgery for diagnosis and symptom relief. Recognizing it can change diagnostic pathways and multidisciplinary management for people with recurrent small-bowel...
A cross‑trust histopathology MDT helped reclassify diagnoses in a substantial proportion of discussed paediatric IBD cases and occasionally changed management or transition planning, which could affect treatment...
Researchers are exploring targeted nanodelivery of miR-497 to reduce oxidative stress and shift immune cells toward tissue-repairing states — a novel preclinical strategy that could eventually lead to new treatments for...
