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Procedures and surgery

Resection, ostomy, J-pouch, strictureplasty, fistula, abscess, and other procedure-related updates.

Page 9 of 11 · 490 articles

Features of the course and therapeutic strategy of ulcerative colitis in liver transplant recipients
Experimental and Clinical Gastroenterology

Features of the course and therapeutic strategy of ulcerative colitis in liver transplant recipients

People with IBD who undergo liver transplantation — especially those with PSC — can have different UC course and treatment needs because transplant immunosuppression and the liver disease itself affect the bowel.

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Further considerations on long-term outcomes following ileal pouch-anal anastomosis for ulcerative colitis.
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

Further considerations on long-term outcomes following ileal pouch-anal anastomosis for ulcerative colitis.

Based on the title and source metadata, this appears to be an opinion or commentary related to Ulcerative colitis and Procedures and surgery. The original article is from Colorectal disease : the official journal of the...

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Lowering the C‐Reactive Protein ( CRP ) Threshold Improves Risk Stratification in Acute Ulcerative Colitis: A Propensity‐Matched Analysis
Alimentary Pharmacology & Therapeutics

Lowering the C‐Reactive Protein ( CRP ) Threshold Improves Risk Stratification in Acute Ulcerative Colitis: A Propensity‐Matched Analysis

Lowering the CRP cutoff could help hospitals identify hospitalized UC patients at higher risk of needing surgery who are currently classified as less severe. That may affect monitoring and treatment decisions during...

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Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis
Advanced Science

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

This study describes a local rectal therapy that combines mesalamine with probiotic‑derived extracellular vesicles to promote mucosal healing and reduce inflammation in ulcerative colitis models, which could point toward...

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High-grade Dysplasia with Pseudocarcinomatous Invasion Mimicking Invasive Carcinoma in a Patient with Ulcerative Colitis
Journal of Gastrointestinal and Liver Diseases

High-grade Dysplasia with Pseudocarcinomatous Invasion Mimicking Invasive Carcinoma in a Patient with Ulcerative Colitis

People with ulcerative colitis undergo surveillance for dysplasia because of an increased risk of colorectal cancer. This case highlights a pathology pattern (pseudocarcinomatous invasion) that can mimic invasive...

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A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community Setting
ClinicalTrials.gov

A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community Setting

This trial tests a common real-world question: switching from IV induction to subcutaneous vedolizumab maintenance in adults with moderate-to-severe UC or CD and measures short-term remission and longer-term treatment...

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Modernizing Aeromedical Standards for Crohn's Disease: A Risk-Stratified, Evidence-Informed Proposal for Waiver Reform.
Military medicine

Modernizing Aeromedical Standards for Crohn's Disease: A Risk-Stratified, Evidence-Informed Proposal for Waiver Reform.

This is relevant because military aviators with Crohn’s disease have historically been excluded from waivers; policy changes could allow some stable patients to continue flying if objective evidence supports low...

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Predictors of ileal pouch–anal anastomosis failure in ulcerative colitis: a European tertiary referral center experience
Techniques in Coloproctology

Predictors of ileal pouch–anal anastomosis failure in ulcerative colitis: a European tertiary referral center experience

This study identifies factors linked to permanent ileal pouch failure after surgery for ulcerative colitis and provides a nomogram to estimate individual risk — information that can affect surgical counseling and...

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‘We need to highlight as a community that these are avoidable’: exploring clinician perspectives on healthcare access and avoidable admissions in inflammatory bowel disease
Frontline Gastroenterology

‘We need to highlight as a community that these are avoidable’: exploring clinician perspectives on healthcare access and avoidable admissions in inflammatory bowel disease

Avoidable unplanned hospital admissions are common and costly for people with IBD. This study suggests many such admissions stem from healthcare access and service delivery problems—not just disease severity—so system...

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Demographic Analysis of Patients With Ulcerative Colitis Undergoing Restorative Proctocolectomy With Ileal Pouch-Anal Anastomosis: A Single-Center Retrospective Study.
Cureus

Demographic Analysis of Patients With Ulcerative Colitis Undergoing Restorative Proctocolectomy With Ileal Pouch-Anal Anastomosis: A Single-Center Retrospective Study.

Pouch surgery is a key restorative option for people with ulcerative colitis, but pouchitis, chronic antibiotic-refractory pouchitis (CARP), pouch failure, and occasional reclassification to Crohn’s disease can cause...

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Clinical efficacy analysis of acupuncture combined with anti-tumor necrosis factor treatment for spleen and kidney yang deficiency type ulcerative colitis.
Frontiers in medicine

Clinical efficacy analysis of acupuncture combined with anti-tumor necrosis factor treatment for spleen and kidney yang deficiency type ulcerative colitis.

The report suggests adding acupuncture to anti-TNF therapy may improve short-term symptom control and mucosal healing and reduce early colectomy risk for a TCM-defined subgroup of ulcerative colitis patients, which could...

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Hepatic and splenic tuberculosis following infliximab therapy for refractory ulcerative colitis: a case report and literature review
BMC Gastroenterology

Hepatic and splenic tuberculosis following infliximab therapy for refractory ulcerative colitis: a case report and literature review

Extrapulmonary TB can be triggered or revealed during immunosuppressive biologic therapy and may mimic other causes of liver injury; early recognition and TB-specific testing are important for timely treatment and to...

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Time trends in strategies for postoperative Crohn's disease management and long-term surgical recurrence: ENEIDA registry data.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Time trends in strategies for postoperative Crohn's disease management and long-term surgical recurrence: ENEIDA registry data.

The findings suggest that over three decades more patients receive medical prevention after ileocolic resection — including thiopurines and biologics — and that rates of needing a second surgery have fallen. This matters...

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Utility of endoscopic ileocecal valve-plasty for Crohn's disease: a propensity-matched retrospective study.
Surgical endoscopy

Utility of endoscopic ileocecal valve-plasty for Crohn's disease: a propensity-matched retrospective study.

People with Crohn’s disease and fibrotic ileocecal valve strictures sometimes face surgery when endoscopic access is blocked by polypoid tissue. A new endoscopic approach (ICVP) aims to remove obstructing tissue so...

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Long-term treatment trajectories and surgical outcomes in Chinese patients with ulcerative colitis
World Journal of Gastroenterology

Long-term treatment trajectories and surgical outcomes in Chinese patients with ulcerative colitis

Shows real-world long-term outcomes in a large Chinese UC cohort and highlights that baseline disease activity predicts need for escalation and colectomy risk; points to opportunities to improve treat-to-target care.

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Rescue Vedolizumab Therapy for a Rare Case of Complicated Severe Ulcerative Colitis: A Case Report and Literature Review.
Journal of clinical medicine

Rescue Vedolizumab Therapy for a Rare Case of Complicated Severe Ulcerative Colitis: A Case Report and Literature Review.

This case report describes successful use of vedolizumab to treat severe UC in a patient who also had PSC and SLE — a rare and complex combination. Patients and clinicians may find it relevant when considering biologic...

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Clinical indications and outcomes of pediatric gastrointestinal endoscopy in a resource-limited healthcare system: Findings from the first multicenter study
PubMed Central

Clinical indications and outcomes of pediatric gastrointestinal endoscopy in a resource-limited healthcare system: Findings from the first multicenter study

Endoscopy in this pediatric multicenter series found a high diagnostic yield and confirmed IBD and other treatable conditions; this matters for families and clinicians in resource-limited settings because improving...

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Risk Factors and Predictive Biomarkers for Postoperative Complications in Crohn's Disease Surgery: Systematic Review.
International journal of molecular sciences

Risk Factors and Predictive Biomarkers for Postoperative Complications in Crohn's Disease Surgery: Systematic Review.

People with Crohn’s disease facing surgery may have varying risks of complications; better biomarkers and models could help tailor perioperative care and decision-making. The review signals active research toward more...

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Vedolizumab for De Novo Ulcerative Colitis After Kidney Transplantation in a Patient With IgA Nephropathy: A Case Report.
Case reports in transplantation

Vedolizumab for De Novo Ulcerative Colitis After Kidney Transplantation in a Patient With IgA Nephropathy: A Case Report.

People with IBD who’ve had organ transplants (or are concerned about infection risk from systemic immunosuppression) may be interested because vedolizumab’s gut‑selective action could be preferable after kidney...

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Application of thermo-responsive polymers as an enema formulation for the treatment of ulcerative colitis.
International journal of pharmaceutics

Application of thermo-responsive polymers as an enema formulation for the treatment of ulcerative colitis.

A rectal 5-ASA gel that forms in place and sticks to the mucosa could reduce leakage and improve drug retention, potentially increasing effectiveness and patient comfort for people using topical therapies for ulcerative...

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Retrospective Study of Open Versus Laparoscopic Ileocecal Resection in Crohn's Disease in an MIS Era: From a Low-to-Middle Income Country Perspective.
Journal of the West African College of Surgeons

Retrospective Study of Open Versus Laparoscopic Ileocecal Resection in Crohn's Disease in an MIS Era: From a Low-to-Middle Income Country Perspective.

Surgical approach (open vs laparoscopic) affects recovery after ileocecal resection — shorter hospital stay and less bleeding with laparoscopy could matter for Crohn’s patients, especially where resources and access to...

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Perianal Crohn Disease in a Patient With Congenital Afibrinogenemia: A Multidisciplinary Therapeutic Management Challenge.
Cureus

Perianal Crohn Disease in a Patient With Congenital Afibrinogenemia: A Multidisciplinary Therapeutic Management Challenge.

People with IBD who also have bleeding disorders face special risks during endoscopy, surgery, and when using immunosuppressive drugs. This case shows that coordinated care and hemostatic support can allow diagnosis and...

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Isolated Transverse Colon Perforation During Corticosteroid Tapering in Quiescent Systemic Lupus Erythematosus: A Histopathology-Supported Diagnosis of Exclusion
Cureus

Isolated Transverse Colon Perforation During Corticosteroid Tapering in Quiescent Systemic Lupus Erythematosus: A Histopathology-Supported Diagnosis of Exclusion

GI perforation is a serious, potentially life-threatening complication that can occur in people with autoimmune diseases; this report highlights that perforation can happen during corticosteroid tapering and that careful...

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Balloon-assisted endoscopic stricturotomy for small bowel fibrostenotic strictures: A comparison of Crohn’s disease-related and non-Crohn’s disease strictures
World Journal of Gastroenterology

Balloon-assisted endoscopic stricturotomy for small bowel fibrostenotic strictures: A comparison of Crohn’s disease-related and non-Crohn’s disease strictures

Patients with small-bowel strictures face repeat procedures or surgery; this study suggests endoscopic stricturotomy outcomes differ by whether the stricture is from Crohn’s disease and that a simple blood marker (NLR)...

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Exosomes from IL-33-Stimulated Macrophages Regulate Epithelial Barrier Function to Ameliorate TNBS-Induced Colitis in Mice.
Cells

Exosomes from IL-33-Stimulated Macrophages Regulate Epithelial Barrier Function to Ameliorate TNBS-Induced Colitis in Mice.

The study identifies a potential biologic approach (macrophage-derived exosomes) that improved epithelial repair and barrier function in a mouse colitis model, which could inform future therapeutic research for IBD.

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Sulfasalazine- and Cerium Ion-Loaded Polymersomes with Enhanced RONS Scavenging and Colonic Mucosal Repair Ameliorate Experimental Colitis.

The work targets oxidative/nitrosative stress and mucosal repair—mechanisms important in IBD—using a novel delivery vehicle that pairs an approved anti-inflammatory drug with catalytic cerium ions. If translated, this...

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Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis
ClinicalTrials.gov

Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis

The trial is testing risankizumab alone and in combination with investigational ABBV antibodies for moderate-to-severe Crohn’s disease and ulcerative colitis — findings could inform future treatment choices and...

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Intestinal Fibrosis in IBD: Rethinking the Inflammatory Paradigm and Emerging Therapeutic Opportunities.
Digestive diseases and sciences

Intestinal Fibrosis in IBD: Rethinking the Inflammatory Paradigm and Emerging Therapeutic Opportunities.

Intestinal fibrosis causes strictures that can lead to obstruction and often require surgery; current drugs mainly reduce inflammation and do not reliably prevent or reverse fibrosis. Advances in understanding fibrosis...

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Comparison of the Efficacy of Different Biologic Agents in Preventing Postoperative Endoscopic Recurrence of Crohn's Disease
ClinicalTrials.gov

Comparison of the Efficacy of Different Biologic Agents in Preventing Postoperative Endoscopic Recurrence of Crohn's Disease

The study is comparing common biologics given after Crohn's surgery to prevent endoscopic recurrence—a key issue for people who have had bowel resection. Knowing which drugs perform better in real‑world practice could...

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