Condition
Broader IBD news covering Crohn's disease, ulcerative colitis, research, treatments, monitoring, and patient care.
Page 41 of 88 · 4203 articles
The paper suggests gut bacteria make an anti-inflammatory metabolite (NOP) that accumulates in IBD and reduces inflammatory responses in cells and multiple mouse colitis models, pointing to a potential microbiome-derived...
Folate deficiency can cause anemia and other health problems; knowing how common it is in people with celiac disease can help guide screening and supplement decisions. The link with coexisting ulcerative colitis may be...
Patients diagnosed with IBD during or shortly after emergency hospital care had substantially worse 1-year outcomes in this large, population-based analysis — highlighting that late or emergency presentation is linked to...
Time-restricted eating could offer a nonpharmacologic way to improve weight and some metabolic measures, and an early small study suggests it might reduce some Crohn’s symptoms in people who are overweight and in...
Prednisone is commonly used short-term in IBD flares; an FDA label update clarifies approved uses and dosing considerations that affect how clinicians prescribe it and how patients should take and stop the drug.
The paper describes plant-derived compounds that reduced inflammation and partly corrected gut microbiome disturbances in lab and mouse models of colitis, suggesting a possible route to microbiome-targeted IBD therapies...
Delays in diagnosing IBD are common and can raise the risk of complications, so understanding when to push for testing matters. The article explains tests and differences between IBS and IBD to help people know when to...
Cure8 could only read part of this source from tradingview.com, so this card uses cautious topic tags instead of a full summary. It is tagged for Crohn's disease, Inflammatory bowel disease, and Access, cost, and policy.
A local athlete’s story shows how Crohn’s disease can be managed while pursuing competitive goals and advocacy; it may encourage others with IBD who face fatigue, pain, or diet-related triggers.
Researchers present a small platelet-related gene signature (TRIM22, TIMP1, RAC2) that may help understand UC biology and point toward blood-based biomarkers. If validated further, such markers might aid noninvasive...
The study describes a new molecular axis (Uhrf1 → PKM2 ubiquitination) that reduced inflammation and pyroptosis in IBD models and identifies a compound (EPT) that promotes this interaction — a potential early-stage...
Biomarker discordance is common in treat-to-target IBD care; understanding which tests reflect local gut inflammation versus systemic response can help avoid unnecessary treatment changes and guide targeted...
CDI is a serious infection that raises the risk of death for people with IBD. This study shows mortality linked to IBD+CDI changed over the last 25 years and that racial, geographic, and urban–rural disparities...
Fucosylation appears to influence intestinal barrier function, host–microbiota interactions, and immune responses — processes central to IBD pathogenesis. If validated, fucosylation-related biomarkers or therapies could...
PSC is closely linked with IBD (especially ulcerative colitis); understanding mechanisms that damage bile ducts could point to new future therapies or biomarkers.
If you or a patient is about to start infliximab for ulcerative colitis, routine blood counts may help identify those unlikely to respond to induction therapy; a high negative predictive value suggests these markers...
This study suggests a new, compact DNA-methylation biomarker that identifies accelerated aging in the colon linked to chronic inflammation (IBD) and pre-cancerous conditions. Such biomarkers could eventually help...
The study suggests that modifiable early-life factors (feeding, antibiotic exposure, activity, BMI, smoke exposure, delivery mode, diet) may influence the later risk of IBD, especially Crohn's disease, which could be...
The study suggests a traditional Chinese medicine formula can reduce disease signs in a mouse model of chronic relapsing ulcerative colitis and that its effects are mediated by changes in the gut microbiota and microbial...
A validated claims-based algorithm could enable larger, more efficient studies of fibrostenosis in Crohn’s disease using real-world data — helping researchers and clinicians better measure how often stricturing...
Researchers are exploring ways to prioritize who needs colonoscopy sooner; adding TCM features to prediction models might change triage performance. Patients and clinicians interested in pre-endoscopic risk tools or...
This trial tests a non-drug way (virtual reality medical-hypnosis content) to reduce pain and embarrassment during rectosigmoidoscopy — a common, sometimes poorly tolerated procedure in ulcerative colitis that patients...
A dietary multi-mineral supplement is being tested in a Phase 2 trial to see if it can improve symptoms, influence inflammation biomarkers, and help induce or maintain remission in people with ulcerative colitis.
This story highlights how hospital billing, administrative errors, and gaps in hospital care (privacy, dietary needs) can create financial and emotional stress for people with Crohn’s disease. It underscores broader...
The study reports an experimental coating that both protects a probiotic and provides antioxidant, anti-inflammatory effects in a mouse colitis model—an approach that, if validated in humans, could improve probiotic...
The study targets macrophage mitochondrial dysfunction, a mechanism linked to inflammation in ulcerative colitis, and demonstrates a nanodelivery approach that reduced colitis in mice—an approach that could inspire new...
A JAK inhibitor (upadacitinib) used for moderate–severe ulcerative colitis can cause neutropenia; this case report discusses how it was identified and managed, which matters for patients on the drug and clinicians...
This analysis suggests enteral nutrition may be more effective than a low-residue diet for clinical response in adults with ulcerative colitis and that some dietary strategies may raise albumin, but the underlying trial...
Basal crypt dysplasia is easy to miss but linked to higher risk of advanced colorectal neoplasia in longstanding IBD. Improved recognition and use of p53 immunohistochemistry or complementary biomarkers could affect...
NUDT15 genotyping can identify people at high risk of severe thiopurine-induced myelosuppression; if cost-effective, testing could change how clinicians choose or dose thiopurines for IBD, potentially preventing serious...
The study suggests a natural seaweed-derived polysaccharide could modify gut bacteria and immune signaling in ways that reduced experimental colitis, which may interest people looking for microbiota-targeted dietary...
Cure8 found this source from Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, but the page could not be read reliably yet....
Endometriosis may coexist with IBD and can cause pelvic pain, painful sex, and heavy periods—symptoms that may be mistaken for bowel disease activity. Identifying endometriosis could change evaluation and management for...
This preclinical study suggests a traditional medicinal plant extract may reduce inflammation and tissue damage in an experimental model of ulcerative colitis, which could guide future drug-discovery research relevant to...
After surgery, many people with IBD experience altered gut function that can cause dehydration, high stool output, and nutrient losses. Borrowing SBS management strategies can help stabilize hydration and nutrition and...
This method helps translate complex paired microbiome and metabolome data into coherent functional modules; that could clarify microbial metabolic alterations in IBD or IBS and guide future biomarker or mechanistic...
The study suggests a dietary/prebiotic compound (2'-FL) can change gut microbes and patient-reported disease control in mild-to-moderate UC, which could point to non-drug ways to support symptoms and microbiome health.
This work suggests that non-immune stromal cells can hold an epigenetic ‘memory’ that keeps intestinal tissue in a disease-promoting state, which may help explain relapse or incomplete responses to immune-focused...
The study points to specific immune pathways (especially Th17 differentiation) and molecular targets that might explain DSP’s anti-inflammatory effects in ulcerative colitis, which could guide further preclinical and...
Researchers used laboratory mouse and cell models to show that total glucosides of paeony (TGP) may reduce inflammation linked to ulcerative colitis and identified molecular pathways (COX‑2/arachidonic acid, NF‑κB, MAPK,...
TL1A-DR3 is implicated in both inflammation and fibrosis in IBD, so targeting it could address active disease and reduce fibrotic complications that lead to strictures. New TL1A-blocking antibodies are already in...
The study links a polyphenol-rich diet to a specific microbiome change and a microbial metabolite (4-HPAA) that reduced inflammation in mouse models — offering a possible mechanism by which diet could influence Crohn's...
This preclinical study identifies a novel peptide (spexin) and a biased signaling pathway (SPX–GALR2–Gq) that reduced colitis in mouse models, suggesting a new target and a designed peptide candidate for future IBD...
Researchers describe a natural peptide that binds IL‑17RA and reduced disease measures in mouse colitis models — a potential new mechanism for reducing gut inflammation and restoring the epithelial barrier that could...
Delays in diagnosis and restricted access to therapies can allow Crohn’s inflammation to progress, increasing the chance of bowel damage and worse outcomes. Progress on earlier detection and better matching of treatments...
Intestinal ultrasound provides a noninvasive, real-time way to see bowel inflammation and may reveal treatment response earlier than symptoms alone. That can help clinicians make timely treatment changes to prevent...
These development programs could expand treatment choices for Crohn’s disease and may eventually address fibrosis and refractory disease—two major unmet needs. Progress in trials could change management options in coming...
Based on the title and source metadata, this appears to be a case report related to Crohn's disease, Inflammatory bowel disease, and Fistula. The original article is from cureus.com.
