Condition
Broader IBD news covering Crohn's disease, ulcerative colitis, research, treatments, monitoring, and patient care.
Page 72 of 88 · 4177 articles
Intestinal fibrosis causes strictures that can lead to obstruction and often require surgery; current drugs mainly reduce inflammation and do not reliably prevent or reverse fibrosis. Advances in understanding fibrosis...
Dietary strategies such as the Crohn’s Disease Exclusion Diet (CDED) may help induce remission for some people with Crohn’s disease and could be an option alongside medical therapy or enteral nutrition. Patients...
Colorectal lymphoma in children can mimic IBD flares or cause surgical emergencies; recognizing this can prevent inappropriate escalation of immunosuppression and speed correct diagnosis and treatment.
The study identifies a sizable group of patients in Latin America with difficult-to-treat IBD—especially Crohn’s disease—highlighting higher disease severity, younger onset, and longer diagnostic delays that can affect...
Researchers are exploring circRNAs as new molecular players in IBD inflammation; that could lead to future biomarker tests or novel treatments targeting immune pathways relevant to Crohn’s disease and ulcerative colitis.
This study suggests a traditional processing method may change a common herbal used for UC so it works better in mouse and cell models, and it proposes a specific molecular pathway (LCN2‑mediated pyroptosis) that could...
Researchers are exploring new ways to deliver regenerative factors and reshape the gut microbiome in IBD.
This preclinical study suggests a ginseng-derived polysaccharide reduced inflammation and tissue injury in cell and mouse models of colitis, which could eventually inform dietary supplements or therapeutic research...
Work participation and job retention are common concerns for people living with IBD. This study will measure how IBD affects work ability, fatigue, mental health, and return-to-work barriers, and aims to create...
The study is comparing common biologics given after Crohn's surgery to prevent endoscopic recurrence—a key issue for people who have had bowel resection. Knowing which drugs perform better in real‑world practice could...
A long-term study that profiles immune cells, genes, diet, and the microbiome could help identify biomarkers that predict flares or response to therapy, which matters to people living with Crohn’s or ulcerative colitis.
Malnutrition is common in Crohn’s disease and more likely during active disease; recognizing it matters because nutritional status affects symptoms, recovery, and treatment tolerance.
Researchers identify a gut microbe (Sutterella species) that may worsen intestinal inflammation by blocking AhR-driven IL-22 and IL-17 responses—pathways that help protect the gut lining.
IBD is increasingly linked with anxiety, depression, and cognitive symptoms; this study suggests gut microbes may change tryptophan metabolism in colitis and contribute to those brain-related symptoms, which could point...
AI tools like Google NotebookLM could make systematic reviews and consensus statement processes faster and less labor-intensive for IBD-related evidence, while maintaining very low rates of major factual errors.
If validated, a blood test for cytotoxic CD4+ T cells at diagnosis could help predict who is less likely to respond to anti‑TNF drugs, potentially allowing earlier selection of alternative therapies for some children...
This review describes a novel, targeted drug-delivery approach being explored for autoimmune diseases including IBD; such technology could in future enable more specific immunomodulation with fewer systemic side effects...
The study shows rapidly rising IBD healthcare costs driven mainly by growing prevalence and biologic therapy spending, which can affect access, insurance coverage, and healthcare planning for people with Crohn’s and...
This paper links specific features of the gut bacterial flagellome to TLR5-driven immune activation and reports a disease-associated shift in flagellin profiles in Crohn’s disease and ulcerative colitis, suggesting...
This study reports real-world data on mirikizumab in adults with ulcerative colitis, focusing on clinical and endoscopic remission and inflammatory markers — outcomes patients and clinicians use to judge treatment...
This NIH natural-history study is collecting clinical, immune, and genetic samples from people with Crohn’s disease and ulcerative colitis to better understand immune pathways and molecular causes of IBD. Those findings...
Mucosal healing is an important treatment goal linked to better long-term outcomes, and current anti-TNF therapies achieve mucosal healing in a minority of patients. If adding CDED improves healing, it could offer a...
Patients and families with pediatric UC may be interested because the study tests FMT plus partial enteral nutrition as a potential new treatment approach for children who haven’t responded to standard therapy and as a...
Adding structured partial enteral nutrition to advanced drug therapy could offer a non-pharmacologic way to improve short-term, steroid-free remission rates in active Crohn's disease if the trial shows benefit.
Genetic primary bile acid malabsorption can produce IBD-like symptoms and may be missed in children labeled with Crohn's disease; recognizing PBAM could change testing and management for some patients.
The paper proposes a specific molecular link between elevated glycocholic acid (a bile acid altered in IBD) and impaired intestinal stem cell renewal via the TRIB3–ID1 pathway, which could help explain poor mucosal...
Understanding and quantifying placebo-driven endoscopic changes can improve design and interpretation of Crohn’s disease trials, which may ultimately speed development of effective therapies and clarify who benefits from...
Capsule endoscopy can be helpful for small-bowel assessment in Crohn’s disease but carries a risk of retention when strictures are present. Retained capsules may be asymptomatic yet still require surgery, so better...
Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Aminosalicylates. The original article is from Digestive Diseases and Sciences.
PSC is rare in the general population but substantially more common in people with IBD, particularly ulcerative colitis, and it raises long-term hepatobiliary risks including cholangiocarcinoma—so knowing how often PSC...
Many people worry that medications taken during pregnancy could affect a child’s long-term health. This large study suggests that prenatal use of acid-suppressive drugs is not clearly linked to a meaningful increase in...
Cure8 found this source from independent.com.mt, but the page could not be read reliably yet. It is tagged for Crohn's disease, Inflammatory bowel disease, and Community and awareness. Open the original article for the...
Faster, accurate diagnosis can let people with Crohn's disease start appropriate treatment sooner and help avoid complications from ongoing inflammation. The article outlines common presenting symptoms and recommended...
Some people with Crohn’s explore diet, exercise, supplements, and functional‑medicine approaches alongside or instead of drugs. This article shares one patient’s drug‑free experience and specific strategies he says...
This trial directly tests common clinical strategies for managing loss of response to ustekinumab in Crohn’s disease. The findings may change whether doctors routinely escalate to 4-weekly dosing after an IV reinduction,...
Many people with Crohn's also have obesity or diabetes and may be prescribed GLP-1 drugs. Understanding safety, symptom overlap, and current research helps you and your care team make informed choices about starting or...
New approvals and pipeline activity can expand future treatment options and affect availability, pricing, and research priorities for Crohn’s disease. Market analyses can signal which therapies companies expect to...
This study suggests a targeted phage can reduce inflammation driven by Crohn’s‑associated E. coli without wiping out the gut microbiome, and it may boost the effect of lower steroid doses. That could eventually mean...
Based on the title and source metadata, this appears to be a clinical study related to Inflammatory bowel disease, Crohn's disease, and Irritable bowel syndrome. The original article is from msn.com.
This study quantifies the large NHS and societal costs of Crohn’s disease and ulcerative colitis in the UK and highlights that ongoing management and maintaining remission are major drivers of expense.
This study suggests a new, targeted way to reduce gut inflammation by disabling harmful E. coli behaviors linked to Crohn's disease without wiping out the microbiome.
Cure8 found this source from academic.oup.com, but the page could not be read reliably yet. It is tagged for Inflammatory bowel disease, Crohn's disease, and Research and clinical trials. Open the original article for...
If correct, the paper points to a previously underappreciated immune cell (GzmK+ tissue-resident CD8+ T cells) as a potential driver of Crohn’s inflammation — which could lead to new biomarkers or therapies that work...
Based on the title and source metadata, this appears to be a patient story related to Crohn's disease, Inflammatory bowel disease, and Symptoms and flares. The original article is from msn.com.
The story shows that emergency surgery and coordinated specialist care can treat life‑threatening Crohn’s complications and help patients regain daily activities. It highlights the role of reconstructive surgery and...
Genetic studies help reveal biological pathways behind Crohn’s disease, which can guide research into new treatments and better understanding of disease mechanisms. People with Crohn’s disease may find it useful to know...
Cure8 found this source from mshale.com, but the page could not be read reliably yet. It is tagged for Crohn's disease, Inflammatory bowel disease, and Community and awareness. Open the original article for the full...
The study pinpoints a genetic cause (BIRC3 variants) that disrupts a TNF/RIPK1 immune pathway linked to Crohn’s disease, suggesting a targetable mechanism. That could help doctors match patients to treatments and guide...
