Fistulas, strictures, obstruction, anemia, cancer risk, extraintestinal symptoms, and related complications.
Page 16 of 20 · 921 articles
The study identifies a food-derived compound that improved colitis in lab models and acted on JAK/STAT3 signaling and intestinal barrier proteins—pathways relevant to IBD inflammation and mucosal healing.
Sexual dysfunction is common in IBD and—according to this study—appears more strongly linked to psychological and demographic factors than to disease activity or muscle loss. Recognizing and treating mental-health issues...
Based on the title and source metadata, this appears to be a clinical study related to Inflammatory bowel disease and Complications. The original article is from Cureus.
Based on the title and source metadata, this appears to be a clinical study related to Crohn's disease, Ulcerative colitis, and Inflammatory bowel disease. The original article is from Journal of Gastroenterology and...
People with Crohn's disease and their clinicians often ask how different treatments affect cancer risk. This large nationwide study provides real-world estimates of absolute excess cancer cases by treatment group, which...
People with ulcerative colitis undergo surveillance for dysplasia because of an increased risk of colorectal cancer. This case highlights a pathology pattern (pseudocarcinomatous invasion) that can mimic invasive...
The article helps patients and caregivers recognize common symptoms and complications, understand causes and risk factors, and see why ongoing specialist care and lifestyle measures matter for long-term management.
Surgery is common in Crohn’s disease and different types of resections carry different short-term risks.
If you have newly diagnosed Crohn’s disease, this study suggests sacroiliac joint inflammation or structural SIJ changes can already be present and may relate to microscopic (histologic) intestinal activity.
Based on the title and source metadata, this appears to be a case report related to Inflammatory bowel disease and Complications. The original article is from Immunopharmacology and Immunotoxicology.
Cure8 indexed source-provided abstract text from OpenAlex, but this record did not meet the threshold for a full Cure8 brief. It is tagged for Colorectal cancer, Inflammatory bowel disease, and Complications.
Markers of systemic inflammation (CRP and ESR) were consistently higher in people with obesity across Crohn’s disease, ulcerative colitis, psoriasis, and psoriatic arthritis, suggesting body weight may influence...
The oral microbiome can influence gut microbes and inflammation; understanding this link could lead to new diagnostic markers (saliva) or combined dental–gastroenterology care approaches relevant to people with IBD.
This review found that children with atopic dermatitis have a modestly higher risk of later developing IBD (both Crohn’s disease and ulcerative colitis). Awareness of this association may help clinicians and families...
Extrapulmonary TB can be triggered or revealed during immunosuppressive biologic therapy and may mimic other causes of liver injury; early recognition and TB-specific testing are important for timely treatment and to...
Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Toxicology Mechanisms...
Respiratory diseases (COPD, asthma, bronchiectasis) and IBD appear to occur together more often than expected. If you have IBD, especially Crohn’s, you may be at higher risk for some obstructive lung diseases, and people...
The study compares two oral steroid therapies used to induce remission in outpatient ulcerative colitis and reports similar short-term efficacy but different safety profiles — information that can inform treatment...
This case report describes successful use of vedolizumab to treat severe UC in a patient who also had PSC and SLE — a rare and complex combination. Patients and clinicians may find it relevant when considering biologic...
If environmental microplastics contribute to gut dysbiosis and mucosal inflammation, this could help explain environmental triggers of ulcerative colitis and point toward prevention or microbiome-targeted interventions.
The FDA label for XELJANZ/XELJANZ XR (tofacitinib) highlights serious safety risks and monitoring steps relevant to people with ulcerative colitis and other autoimmune conditions who may be using or considering this JAK...
The study identifies a cellular mechanism by which arctigenin reduced inflammatory macrophage death and improved colitis in mice, suggesting a potential new target (macrophage FAO → GSDMD) for therapies or...
If true, a common gut microbe (Fusobacterium nucleatum) and its metabolite succinic acid could worsen intestinal inflammation by changing macrophage behavior, suggesting new targets to reduce flares or mucosal injury in...
Algorithms guide how UC is diagnosed and monitored (endoscopy, labs, fecal markers, imaging) and when to escalate to surgery or other interventions; that affects surveillance, treatment choices, and complication...
The study suggests dietary tryptophan might reduce bacterial-induced acute lung injury in the context of colitis by altering gut–lung immune signaling, which could be relevant to IBD patients who are at risk for...
People with Crohn’s disease facing surgery may have varying risks of complications; better biomarkers and models could help tailor perioperative care and decision-making. The review signals active research toward more...
The work links intestinal inflammation with neurobehavioral changes in a mouse colitis model and suggests certain p‑coumaric acid derivatives can reduce inflammation and anxiety/depression‑like behaviors, which could...
The study presents a mitochondria-targeted compound that reduced necrosis markers, HMGB1, and IL-1β in cell and mouse colitis models, highlighting a potential new pathway for IBD treatment research.
People with IBD who’ve had organ transplants (or are concerned about infection risk from systemic immunosuppression) may be interested because vedolizumab’s gut‑selective action could be preferable after kidney...
People with ulcerative colitis commonly experience depression; understanding whether the relationship is causal and which blood proteins might mediate it could help researchers develop biomarkers or new therapies...
The paper identifies Candida albicans–reactive Th17 cells that travel between oral and gut mucosa and become more pathogenic in Crohn’s disease, suggesting a fungal–immune link that could matter for disease mechanisms...
This review collects preclinical evidence that a traditional Chinese medicine formula (Gegen Qinlian Decoction) may act on inflammation, the gut barrier, immunity, and microbiota — all relevant to ulcerative colitis and...
This study points to a specific immune pathway (IRF5 repressing S100A9) that controls suppressive granulocytic MDSCs in ulcerative colitis, suggesting a new target for therapies aimed at modulating harmful inflammation.
This study identifies an immune pathway (IDO–AhR) that a parasite-derived antigen appears to activate to reduce experimental colitis in mice. That pathway is relevant because it helps explain how immune regulation might...
Fibrosis and stricturing are key problems in Crohn’s disease with limited therapies; this study identifies a microbiota–bile acid–GPBAR1 pathway by which a specific probiotic mix reduced inflammation and fibrosis in...
CMV reactivation can worsen outcomes in active UC and influence treatment choices; clinicians and patients may benefit from additional, easy-to-measure markers that flag higher risk of tissue CMV and prompt targeted...
People with long-standing ulcerative colitis face an increased risk of colorectal cancer; this study highlights PPARGC1A as a gene that may be downregulated early in that progression, which could eventually help identify...
The review shows increasing research linking ferroptosis to autoimmune diseases including IBD and ulcerative colitis, which may guide future biomarker and therapy research relevant to people with Crohn's disease or other...
A blood biomarker that rises with active ulcerative colitis could help patients and clinicians monitor disease activity without relying solely on invasive tests. This study reports that serum type 23 collagen ectodomain...
This large, population-based study suggests people with Crohn's disease have modestly higher overall mortality than matched controls and higher deaths from specific causes (colorectal cancer, renal disease, non-Hodgkin...
People with ulcerative colitis who have had colectomy can rarely develop inflammation of the small intestine and high-output stomas that are hard to control.
If validated, the study points to a specific neutrophil subset that may drive inflammation and barrier damage in IBD, and to CXCR4 as a possible therapeutic target. That could open new biology-based treatment approaches...
People with IBD who also have bleeding disorders face special risks during endoscopy, surgery, and when using immunosuppressive drugs. This case shows that coordinated care and hemostatic support can allow diagnosis and...
If you have IBD — especially Crohn’s — this study suggests your long-term risk of needing dialysis or a kidney transplant may be higher than the general population. Certain treatments and prior bowel surgery were linked...
People with UC have higher rates of low bone density, which raises fracture risk. This study links altered hormones (leptin, ghrelin, IGF‑1) and inflammation to lower BMD in UC, suggesting metabolic pathways that could...
Endometriosis involving the intestine can mimic Crohn’s disease symptoms and lead to misdiagnosis or delayed correct treatment. Patients with IBD-like symptoms who are of reproductive age may need evaluation for bowel...
Reports a rare mesenteric fibroinflammatory complication in a patient with UC who was in remission on vedolizumab, raising a hypothesis about possible associations worth further study.
GI perforation is a serious, potentially life-threatening complication that can occur in people with autoimmune diseases; this report highlights that perforation can happen during corticosteroid tapering and that careful...
